Abstract: The invention provides an in vitro method for non-invasive preimplantation assessment of an embryo by comprising amplifying and detecting a nucleic acid sequence of interest indicative of a genetic deficiency from a sample taken from the in vitro culture medium of the embryo and assessing the embryo as having a genetic deficiency if the presence of the sequence of interest is detected in the in vitro culture medium of the embryo. The examples show the detection of SNPs relating to the genes MDR1 and prothrombin and the SNP responsible for the Leiden syndrome. The application also mentions the possibility of establishing short tandem repeat (STR) marker profiles of DNA in the culture medium and full genome sequencing of the DNA in the culture medium as a means for determining embryo quality.

Abstract: Embodiments of the present invention provide a method for managing a maintenance plan of a machine. The method may include analyzing data, retrieved from a plurality of sources, that makes up a maintenance plan for the machine or any of its components. The method may also include displaying the analysis in a consolidated view to a user. The embodiments may be implemented using a workbench, which is an analytical tool, implementable by processor software, hardware, or a combination thereof. Exemplary applications include aircraft maintenance.

Abstract: Embodiments of the present invention provide a method for managing a maintenance plan of a machine. The method may include analyzing data, retrieved from a plurality of sources, that makes up a maintenance plan for the machine or any of its components. The method may also include displaying the analysis in a consolidated view to a user. The embodiments may be implemented using a workbench, which is an analytical tool, implementable by processor software, hardware, or a combination thereof. Exemplary applications include aircraft maintenance.

Abstract: An aircraft maintenance monitoring system is provided. The maintenance system monitors the operator's compliance with various technical and safety requirements imposed by various entities such as regulatory agencies, manufacturers, operators, and the like. The maintenance monitoring system provides a data structure that configures various technical objects and maintenance tasks in a hierarchical tree using object links. Such a data structure provides dynamics and flexibility to the aircraft maintenance monitoring system. This, in turn, allows updates to be automatically incorporated to the existing maintenance plans and maintenance schedule without any duplicate operations.