Abstract: A laser system for ophthalmic surgery includes a laser source to produce a surgical pulsed laser beam, an XY scanner to scan the surgical pulsed laser beam in XY transverse directions, a Z scanner, to scan the XY scanned laser beam along a Z axis, an objective, to focus the XYZ scanned beam into a focal spot in a target region, and a computational controller, to use a computational process to control at least one of the Z scanner and the XY scanner, to control an optical distortion of the focused scanned beam.

Abstract: A method of photodisruptive laser surgery includes selecting a target region of a tissue for fragmentation, directing a beam of laser pulses to the selected target region of the tissue, and forming cells in the target region of the tissue by directing the laser beam to generate cell boundaries. The cells can be arranged in regular or irregular arrays. The cells can be generated in parallel or successively, with cell sizes and laser parameters which reduce the time of ophthalmic surgery considerably.

Abstract: A patient interface for an ophthalmic system can include an attachment module, attachable to the ophthalmic system, and a contact module, configured to accommodate a viscoelastic substance between the patient interface and a procedure eye. The viscoelastic substance can include a fluid, a liquid, a gel, a cream, an artificial tear, a film, an elastic material, or a viscous material. The refractive index of the viscoelastic substance can be within a range of approximately 1.24-1.52 at an operating wavelength of the ophthalmic system. The patient interface can further include input ports, output ports, and a suction system. It can be an integrated design or a multi-piece patient interface. The viscoelastic substance can be provided by injection, on the cornea, at the contact module, or in a space bounded by soft elastic films or membranes, such as in a bag.

Abstract: A surgical laser system can include a laser engine to generate a laser beam of laser pulses; a scanning delivery system to direct the laser beam to a target region and to scan the laser beam along a scan-pattern in the target region; and a spatio-temporal modulator to perform a space- and time dependent modulation of the laser beam. The spatio-temporal modulation of the phases or amplitudes of the beam components can reduce or even eliminate uncut regions in the target region, caused by the destructive interference of the beam components brought about by a wrinkling of a portion of the target or by other beam distorting factors.

Abstract: A patient interface for an ophthalmic system can include an attachment module, attachable to the ophthalmic system, and a contact module, configured to accommodate a viscoelastic substance between the patient interface and a procedure eye. The viscoelastic substance can include a fluid, a liquid, a gel, a cream, an artificial tear, a film, an elastic material, or a viscous material. The refractive index of the viscoelastic substance can be within a range of approximately 1.24-1.52 at an operating wavelength of the ophthalmic system. The patient interface can further include input ports, output ports, and a suction system. It can be an integrated design or a multi-piece patient interface. The viscoelastic substance can be provided by injection, on the cornea, at the contact module, or in a space bounded by soft elastic films or membranes, such as in a bag.

Abstract: To improve the precision of ophthalmic surgical procedures by reducing corneal wrinkling, a patient interface for an ophthalmic system can include an attachment portion, configured to attach the patient interface to a distal end of the ophthalmic system; a contact portion, configured to dock the patient interface to an eye; and a contact element, coupled to the contact portion, configured to contact a surface of a cornea of the eye as part of the docking of the patient interface to the eye, and having a central portion with a central radius of curvature Rc and a peripheral portion with a peripheral radius of curvature Rp, wherein Rc is smaller than Rp.

Abstract: Techniques, apparatus and systems for laser surgery including imaging-guided surgery techniques, apparatus and systems.

Abstract: Techniques, apparatus and systems for laser surgery including imaging-guided surgery techniques, apparatus and systems.

Abstract: A laser oscillator to generate a pulsed light beam includes an output coupler mirror, configured to reflect a reflected portion of the pulsed light beam back into the laser oscillator, and to couple an outputted portion of the pulsed light beam out from the laser oscillator; an end-mirror, configured to return the pulsed light beam into the laser oscillator; a gain material, positioned between the output coupler mirror and the end-mirror along an optical path, configured to amplify the pulsed light beam; a self-starting saturable absorber, configured to self-start a pulsed mode-locking operation of the laser oscillator; and a pulse-shaping saturable absorber, configured to shape pulses of the pulsed light beam into laser pulses with a pulse length of less than 1,000 femtoseconds.

Abstract: An ophthalmic surgical laser system includes a laser engine, to generate a laser beam, a first Z scanner, to receive the generated laser beam, and to scan a focal spot of the laser system over a first Z interval along an optical axis of the laser system an XY scanner, to receive the laser beam output by the first Z scanner, and to scan the focal spot of the laser system in a direction essentially transverse to the optical axis of the laser system, and a second Z scanner, to receive the scanned laser beam from the XY scanner, and to scan the focal spot of the laser system over a second Z interval along the optical axis of the laser system.

Abstract: A system for interfacing a surgical laser with an eye includes a first sensing element to couple to an output surface of the laser, an interface lens having second sensing element coupled to a first surface of the interface lens, and a detector coupled to the first sensing element. A second surface of the interface lens contacts the eye. The detector determines when the first sensing element contacts the second sensing element. A method for aligning the laser with the eye includes coupling the laser to the patient interface, sensing an electrical change indicating a position of the output surface with the interface lens, comparing the electrical change with a predetermined value to produce a correction, and re-positioning the laser with the correction.

Abstract: A surgical laser system can include a laser engine to generate a laser beam of laser pulses; a scanning delivery system to direct the laser beam to a target region and to scan the laser beam along a scan-pattern in the target region; and a spatio-temporal modulator to perform a space- and time dependent modulation of the laser beam. The spatio-temporal modulation of the phases or amplitudes of the beam components can reduce or even eliminate uncut regions in the target region, caused by the destructive interference of the beam components brought about by a wrinkling of a portion of the target or by other beam distorting factors.

Abstract: A surgical laser system can include a laser engine to generate a laser beam of laser pulses, a scanning delivery system to direct the laser beam to a target region and to scan the laser beam along a scan-pattern in the target region, and a pupil system to modulate the laser beam. In addition, a method of adjusting a pupil of a laser beam can include: generating a laser beam of laser pulses with a laser engine, directing the laser beam to a target region with a scanning delivery system, scanning the laser beam along a scan-pattern in the target region with the scanning delivery system, and performing a modulation of the laser beam with an adjustable pupil system.

Abstract: Systems and techniques for providing variable scanning control in delivering a laser beam of laser pulses to a surgical target are provided. The described systems and techniques can be used for laser surgery within the anterior segment of the eye and the crystalline lens via photodisruption caused by laser pulses from a femtosecond laser.

Abstract: A laser system for ophthalmic surgery includes a laser engine to generate a pulsed laser beam, and an XY scanner, to receive the generated pulsed laser beam, and to output a scanning laser beam, the XY scanner including an X scanner, including two X scanning minors, and a Y scanner, including two Y scanning minors. The XY scanner can modify essentially independently an angle the outputted scanning laser beam makes with an optical axis, and a position at which the outputted scanning laser beam intersects a subsequent reference plane perpendicular to the optical axis.

Abstract: A variable-applanation patient interface can include a lens support system, attachable to a distal end of an ophthalmic surgical laser system; a contact lens, supported by the lens support system and configured to make contact with an eye-surface; and an adjustable coupler, coupled to at least one of the lens support system and the contact lens, and configured to be coupled to a non-central region of the eye-surface, to accommodate the contact lens to contact a central region of the eye-surface with a central applanation, to enable a change between the central applanation and an extended applanation, and to accommodate the contact lens to contact an extended region of the eye-surface larger than the central region with the extended applanation.

Abstract: An ophthalmic system is provided that includes an ophthalmic imaging device to generate an image of a portion of an imaged eye of a patient, an image processor to determine a misalignment of the imaged eye and the imaging device by processing the generated image, and to generate a control signal according to the determined misalignment, and a misalignment-reduction system to receive the control signal, and to generate a misalignment-reduction response. The misalignment-reduction system can include a fixation light system or a gantry. In some cases a locator light system may provide additional alignment information for the image processor.

Abstract: A laser system for ophthalmic surgery includes a laser source to generate a pulsed laser beam, an XY scanner to receive the pulsed laser beam and to output an XY-scanning beam, scanned in two directions transverse to a Z direction, a Z scanner in a scanner housing to receive the XY-scanning beam and to output an XYZ-scanning beam scanned additionally in the Z direction, a mirror to deflect the XYZ-scanning beam received from the Z scanner, and an objective, in an objective housing, to receive the deflected XYZ-scanning beam and to focus the received XYZ-scanning beam onto a target region, wherein the scanner housing is separate from the objective housing.

Abstract: Optical imaging techniques and systems provide high-fidelity optical imaging based on optical coherence tomographic imaging and can be used for optical imaging in ophthalmic surgery and imaging-guided surgery. One method for imaging an eye includes positioning the eye relative to a Spectral Domain Optical Coherence Tomographic (SD-OCT) imaging system, the eye having a first and a second structure, and imaging the eye with the SD-OCT imaging system by selecting one of a direct image and a mirror image of the first eye-structure and generating a first image-portion corresponding to the selected image of the first eye-structure, selecting one of a direct image and a mirror image of the second eye-structure and generating a first image-portion corresponding to the selected image of the second eye-structure, and suppressing the non-selected images of the first and second structures.

Abstract: An ophthalmic docking system is presented that can reduce a condensation of a patient interface of a surgical laser system. The ophthalmic docking system includes a patient interface that has a proximal portion configured to be attached to an ophthalmic system, a distal portion configured to be attached to an eye that includes a contact lens and an interface attachment system; and a decondenser, coupled to the patient interface and configured to reduce a vapor condensation on the contact lens.