Abstract: The present disclosure relates to the field of endoscopy. Specifically, the present disclosure relates to delivery systems and methods for coagulating sites of bleeding within mucosal tissues, and in particular, for eradicating esophageal varices.

Abstract: Methods and devices for treating a lung are disclosed. The method may include deploying a catheter into an airway of the lung, and discharging a media into the airway through the catheter. The media may be configured to increase elasticity of lung tissue in the vicinity of the airway or occlude the airway.

Abstract: A delivery catheter as disclosed herein may be configured in various embodiments to minimize the potential for entanglement between cardiac repair components such as between sutures and coupled anchors. In various embodiments this is achieved by separating an anchor translation channel from a suture translation channel while maintaining the coupling between the anchor and the suture.

Abstract: The present disclosure relates to the field of endoscopy. Specifically, the present disclosure relates to delivery systems and methods for coagulating sites of bleeding within mucosal tissues, and in particular, for eradicating esophageal varices.

Abstract: A vascular closure system for sealing an opening in a blood vessel may include an introducer sheath extending through the opening, the introducer sheath having a lumen extending through the introducer sheath, wherein partial withdrawal of the introducer sheath from the opening everts tissue of the blood vessel at the opening, and a shaping sheath slidably disposed over the introducer sheath, the shaping sheath having a split distal portion configured to engage the everted tissue.

Abstract: A heart valve remodeling device may include a delivery device including an inner shaft slidably disposed over a guidewire and an outer shaft slidably disposed over the inner shaft, and a braided stent fixedly attached to the inner shaft and the outer shaft. The braided stent may be translatable between an elongated configuration and a deployed configuration by movement of the inner shaft relative to the outer shaft. The braided stent may include a valve having two or more leaflets disposed within the braided stent. Adjacent leaflets of the two or more leaflets may form longitudinally-oriented commissures proximate a perimeter of the valve, the commissures being fixedly secured to the braided stent along their length.

Abstract: The present disclosure relates to the field of endoscopy. Specifically, the present disclosure relates to delivery systems and methods for coagulating sites of bleeding within mucosal tissues, and in particular, for eradicating esophageal varices.

Abstract: A medical implant for a left atrial appendage may include a central member having an anchor at a distal end and a plurality of legs joined together at a joint coupled to the central member. The plurality of legs may be configured to expand from a delivery configuration to a deployed configuration. A medical implant may include a central shaft having an anchor at a distal end and a cup-shaped occluder fixed to a proximal end of the central shaft, the occluder being configured to expand from a delivery configuration to a deployed configuration and retard tissue ingrowth thereon. A medical implant system may include a delivery sheath, an implant having an expandable frame including a plurality of legs each having an anchor and a mesh having a plurality of openings therethrough attached to the frame, and a plurality of particles disposed within the delivery sheath.

Abstract: The disclosure pertains to an apparatus for maintaining patency within vessels in the vicinity of surgical procedures which might otherwise be compressed and partially or totally occluded and methods of use therefor.

Abstract: Methods and devices for treating a lung are disclosed. The method may include deploying a catheter into an airway of the lung, and discharging a media into the airway through the catheter. The media may be configured to increase elasticity of lung tissue in the vicinity of the airway or occlude the airway.

Abstract: A heart valve remodeling device may include a delivery device including an inner shaft slidably disposed over a guidewire and an outer shaft slidably disposed over the inner shaft, and a braided stent fixedly attached to the inner shaft and the outer shaft. The braided stent may be translatable between an elongated configuration and a deployed configuration by movement of the inner shaft relative to the outer shaft. The braided stent may include a valve having two or more leaflets disposed within the braided stent. Adjacent leaflets of the two or more leaflets may form longitudinally-oriented commissures proximate a perimeter of the valve, the commissures being fixedly secured to the braided stent along their length.

Abstract: Methods and devices for treating a lung are disclosed. The method may include deploying a catheter into an airway of the lung, and discharging a media into the airway through the catheter. The media may be configured to increase elasticity of lung tissue in the vicinity of the airway or occlude the airway.

Abstract: A vascular closure system for sealing an opening in a blood vessel may include an introducer sheath extending through the opening, the introducer sheath having a lumen extending through the introducer sheath, wherein partial withdrawal of the introducer sheath from the opening everts tissue of the blood vessel at the opening, and a shaping sheath slidably disposed over the introducer sheath, the shaping sheath having a split distal portion configured to engage the everted tissue.

Abstract: The disclosure pertains to an apparatus for maintaining patency within vessels in the vicinity of surgical procedures which might otherwise be compressed and partially or totally occluded and methods of use therefor.

Abstract: The present disclosure relates to the field of endoscopy. Specifically, the present disclosure relates to delivery systems and methods for coagulating sites of bleeding within mucosal tissues, and in particular, for eradicating esophageal varices.

Abstract: A medical implant for a left atrial appendage may include a central member having an anchor at a distal end and a plurality of legs joined together at a joint coupled to the central member. The plurality of legs may be configured to expand from a delivery configuration to a deployed configuration. A medical implant may include a central shaft having an anchor at a distal end and a cup-shaped occluder fixed to a proximal end of the central shaft, the occluder being configured to expand from a delivery configuration to a deployed configuration and retard tissue ingrowth thereon. A medical implant system may include a delivery sheath, an implant having an expandable frame including a plurality of legs each having an anchor and a mesh having a plurality of openings therethrough attached to the frame, and a plurality of particles disposed within the delivery sheath.

Abstract: An implantable heart system for the treatment of a heart with impaired function. The implantable heart system includes a prosthetic heart chamber assembly and a cooperative mechanism. The prosthetic heart chamber assembly comprises a first prosthesis, a second prosthesis, and a prosthetic heart chamber interconnecting the first and second prostheses. One of the prostheses is a valve and the other prosthesis is either a valve or a tubular prosthesis. The cooperative mechanism is selected from the group consisting of an adhesive; an anchor; a filler material; a shape memory element; an expandable member; a pumping agent; material attached to, or forming a part of, the wall of the prosthetic heart chamber; and combinations thereof.

Abstract: A method of treating a disease of the lung may include inserting an implant into the circulatory system. The implant may include an agent configured to be released into the circulatory system over time to deliver the agent to the lungs. The agent may be configured to treat a disease of the lung.

Abstract: Exemplary embodiments of a method for assisting breathing in a lung having damaged tissue are disclosed. The method may include inserting an implant containing a dilatant fluid into a pleural cavity of a patient to reduce an inhalation volume of the lung. Additional embodiments may include an implant configured to apply a force toward a portion of a lung. A controller may be coupled to the implant and configured to sense a biological event and control an amount of outwardly directed force applied by the implant to the lung in response to the biological event. Further, a method may include applying a force to an organ via an implant to expel material from the organ and adjusting the implant so as to transition between a first configuration and a second configuration. The implant may include at least one of an electro-active material and a pressure sensitive material.

Abstract: Methods and devices for treating a lung are disclosed. The method may include deploying a catheter into an airway of the lung, and discharging a media into the airway through the catheter. The media may be configured to increase elasticity of lung tissue in the vicinity of the airway or occlude the airway.