Patents by Inventor Feridoun Karimi-Busheri

Feridoun Karimi-Busheri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETING DNA REPAIR IN TUMOR CELLS VIA INHIBITION OF ERCC1-XPF
    Publication number: 20220306603
    Abstract: The current application relates to pyronaridine or 6-chloro-2-methoxyacridine analogs having binding affinity for the ERCC1-XPF hetero-dimerization interface. The compounds can be used for targeting DNA repair in tumor cells via ER-CC1-XPF inhibition, therefore improving the therapeutic benefit of irradiation or other cancer treatment, or reducing the dosage and adverse effects associated with such treatment.
    Type: Application
    Filed: June 12, 2020
    Publication date: September 29, 2022
    Inventors: Frederick WEST, Jack TUSZYNSKI, Michael WEINFELD, Khaled Hassan BARAKAT, Ahmed H. ELMENOUFY, Francesco GENTILE, Feridoun KARIMI-BUSHERI, Claudia WEILBEER
  • Small molecule inhibitors of polynucleotide kinase/phosphatase, poly(ADP-ribose) polymerase and uses thereof
    Patent number: 9694073
    Abstract: The present invention generally relates to use of compounds and compositions as a chemosensitizers and/or radiosensitizers and/or inhibitors of PNKP phosphatase activity. The present invention provides pharmaceutical combinations and/or a pharmaceutically acceptable salt thereof, kits containing such compounds and/composition and methods of using such compounds and/or compositions.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: July 4, 2017
    Assignees: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA, ALBERTA HEALTH SERVICES
    Inventors: Michael Weinfeld, Dennis G. Hall, Feridoun Karimi-Busheri, Gary Kenneth Freschauf, Todd Randall Mereniuk
  • SMALL MOLECULE INHIBITORS OF POLYNUCLEOTIDE KINASE/PHOSPHATASE, POLY(ADP-RIBOSE) POLYMERASE AND USES THEREOF
    Publication number: 20150306219
    Abstract: The present invention generally relates to use of compounds and compositions as a chemosensitizers and/or radiosensitizers and/or inhibitors of PNKP phosphatase activity. The present invention provides pharmaceutical combinations and/or a pharmaceutically acceptable salt thereof, kits containing such compounds and/composition and methods of using such compounds and/or compositions.
    Type: Application
    Filed: April 30, 2015
    Publication date: October 29, 2015
    Inventors: Michael WEINFELD, Dennis G. HALL, Feridoun KARIMI-BUSHERI, Gary Kenneth FRESCHAUF, Todd Randall MERENIUK
  • Small molecule inhibitors of polynucleotide kinase/phosphatase, poly(ADP-ribose) polymerase and uses thereof
    Patent number: 9040551
    Abstract: The present invention generally relates to use of compounds and compositions as a chemosensitizers and/or radiosensitizers and/or inhibitors of PNKP phosphatase activity. The present invention provides pharmaceutical combinations and/or a pharmaceutically acceptable salt thereof, kits containing such compounds and/composition and methods of using such compounds and/or compositions.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: May 26, 2015
    Assignees: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA, ALBERTA HEALTH SERVICES
    Inventors: Michael Weinfeld, Dennis G. Hall, Feridoun Karimi-Busheri, Gary Kenneth Freschauf, Todd Randall Mereniuk
  • COMPOSITIONS FOR TREATMENT OF CANCER
    Publication number: 20140194465
    Abstract: Compounds that are specifically toxic to cancer stem cells are disclosed.
    Type: Application
    Filed: March 13, 2013
    Publication date: July 10, 2014
    Inventors: Feridoun KARIMI-BUSHERI, Habib FAKHRAI
  • COMPOSITIONS FOR TREATMENT OF CANCER
    Publication number: 20140194507
    Abstract: Compounds that are specifically toxic to cancer stem cells are disclosed.
    Type: Application
    Filed: March 13, 2013
    Publication date: July 10, 2014
    Inventors: Feridoun KARIMI-BUSHERI, Habib FAKHRAI
  • COMPOSITIONS FOR TREATMENT OF CANCER
    Publication number: 20140194478
    Abstract: Compounds that are specifically toxic to cancer stem cells are disclosed.
    Type: Application
    Filed: March 13, 2013
    Publication date: July 10, 2014
    Inventors: Feridoun KARIMI-BUSHERI, Habib FAKHRAI
  • COMPOSITIONS FOR TREATMENT OF CANCER
    Publication number: 20140194429
    Abstract: Compounds that are specifically toxic to cancer stem cells are disclosed.
    Type: Application
    Filed: March 13, 2013
    Publication date: July 10, 2014
    Inventors: Feridoun KARIMI-BUSHERI, Habib FAKHRAI
  • COMPOSITIONS FOR TREATMENT OF CANCER
    Publication number: 20140194463
    Abstract: Compounds that are specifically toxic to cancer stem cells are disclosed.
    Type: Application
    Filed: March 13, 2013
    Publication date: July 10, 2014
    Inventors: Feridoun KARIMI-BUSHERI, Habib FAKHRAI
  • SMALL MOLECULE INHIBITORS OF POLYNUCLEOTIDE KINASE/PHOSPHATASE, POLY(ADP-RIBOSE) POLYMERASE AND USES THEREOF
    Publication number: 20120142721
    Abstract: The present invention generally relates to use of compounds and compositions as a chemosensitizers and/or radiosensitizers and/or inhibitors of PNKP phosphatase activity. The present invention provides pharmaceutical combinations and/or a pharmaceutically acceptable salt thereof, kits containing such compounds and/composition and methods of using such compounds and/or compositions.
    Type: Application
    Filed: June 4, 2010
    Publication date: June 7, 2012
    Applicants: ALBERTA HEALTH SERVICES, THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Michael Weinfeld, Dennis G. Hall, Feridoun Karimi-Busheri, Gary Kenneth Freschauf, Todd Randall Mereniuk