Patents by Inventor Fern SHA

Fern SHA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD98 BINDING CONSTRUCTS FOR TREATING BRAIN TUMORS
    Publication number: 20260337295
    Abstract: Provided are novel multispecific antibodies comprising at least one of a first antigen-binding region and a second antigen-binding region each capable of binding specifically to human epidermal growth factor receptor 2 (HER2), and a third antigen-binding region capable of binding specifically to CD98.
    Type: Application
    Filed: July 28, 2023
    Publication date: October 29, 2026
    Inventors: Wan Cheung CHEUNG, Suzanne EDAVETTAL, James PATTERSON, Matthew BUSCHMAN, Justin SCHEER, Fern SHA, Isha TANEJA
  • TRANSFERRIN RECEPTOR BINDING PROTEINS FOR TREATING BRAIN TUMORS
    Publication number: 20260049155
    Abstract: Provided are novel multispecific antibodies comprising at least one of a first antigen-binding region and a second antigen-binding region each capable of binding specifically to human epidermal growth factor receptor 2 (HER2), and a third antigen-binding region capable of binding specifically to transferrin receptor (TfR).
    Type: Application
    Filed: July 28, 2023
    Publication date: February 19, 2026
    Inventors: Wan Cheung CHEUNG, Suzanne EDAVETTAL, James PATTERSON, Matthew BUSCHMAN, Justin SCHEER, Fern SHA, Isha TANEJA
  • Reversibly switchable fluorescent protein-based indicators
    Patent number: 12072340
    Abstract: Reversibly switchable fluorescent protein-based indicators are disclosed, and can be used as neuronal activity markers. The disclosed reversibly switchable fluorescent protein-based indicators exhibit faster or slower photoswitching the presence or absence of calcium, and depending on the wavelength of light stimulus employed.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: August 27, 2024
    Assignee: HOWARD HUGHES MEDICAL INSTITUTE
    Inventors: Eric R. Schreiter, Fern Sha
  • HUMANIZED ANTIBODIES AGAINST PAIRED HELICAL FILAMENT TAU AND USES THEREOF
    Publication number: 20240166731
    Abstract: Humanized anti-PHF-tau antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, conjugates and fusion constructs of the antibodies, compositions comprising the antibodies, methods of producing the antibodies and using the antibodies for treating or preventing conditions such as tauopathies.
    Type: Application
    Filed: March 25, 2022
    Publication date: May 23, 2024
    Inventors: Rupesh Nanjunda, Partha Chowdhury, Fern Sha
  • REVERSIBLY SWITCHABLE FLUORESCENT PROTEIN-BASED INDICATORS
    Publication number: 20210215725
    Abstract: Reversibly switchable fluorescent protein-based indicators are disclosed, and can be used as neuronal activity markers. The disclosed reversibly switchable fluorescent protein-based indicators exhibit faster or slower photoswitching the presence or absence of calcium, and depending on the wavelength of light stimulus employed.
    Type: Application
    Filed: March 22, 2019
    Publication date: July 15, 2021
    Inventors: Eric R. SCHREITER, Fern SHA