Abstract: An exemplary system, method and computer-accessible medium for generating an image(s) of a portion(s) of a patient(s) can be provided, which can include, for example, receiving first information associated with a combination of positron emission tomography (PET) information and magnetic resonance imaging (MRI) information, generating second information by applying a convolutional neural network(s) (CNN) to the first information, and generating the image(s) based on the second information. The PET information can be fluorodeoxyglucose PET information. The CNN(s) can include a plurality of convolution layers and a plurality of parametric activation functions. The parametric activation functions can include, e.g., a plurality of parametric rectified linear units. Each of the convolution layers can include, e.g., a plurality of filter kernels. The PET information can be reconstructed using a maximum likelihood estimation (MLE) procedure to generate a MLE image.

Abstract: An exemplary system, method and computer-accessible medium for generating an image(s) of a portion(s) of a patient(s) can be provided, which can include, for example, receiving first information associated with a combination of positron emission tomography (PET) information and magnetic resonance imaging (MRI) information, generating second information by applying a convolutional neural network(s) (CNN) to the first information, and generating the image(s) based on the second information. The PET information can be fluorodeoxyglucose PET information. The CNN(s) can include a plurality of convolution layers and a plurality of parametric activation functions. The parametric activation functions can include, e.g., a plurality of parametric rectified linear units. Each of the convolution layers can include, e.g., a plurality of filter kernels. The PET information can be reconstructed using a maximum likelihood estimation (MLE) procedure to generate a MLE image.

Abstract: Exemplary system, method and computer-accessible medium for determining a difference(s) between two sets of subjects, can be provided. Using such exemplary system, method and computer-accessible medium, it is possible to receive first imaging information related to a first set of subjects of the two sets of the subjects, receive second imaging information related to a second set of subjects of the two sets of subjects, generate third information by performing a decomposition procedure(s) on the first imaging information and the second information, and determine the difference(s) based on the third information.

Abstract: An exemplary system, method and computer-accessible medium for generating a magnetic resonance (MR) image(s) and a positron emission tomography (PET) image(s) of a tissue(s) can be provided, which can include, for example, receiving information related to a combination of MR data and PET data as a single data set, separating the information into at least two dimensions, at least one first of the dimensions corresponding to the MR data and at least one second of the dimensions corresponding to the PET data, and generating the MR image(s) and the PET image(s) based on the separated information.

Abstract: Exemplary system, method and computer-accessible medium for determining a difference(s) between two sets of subjects, can be provided. Using such exemplary system, method and computer-accessible medium, it is possible to receive first imaging information related to a first set of subjects of the two sets of the subjects, receive second imaging information related to a second set of subjects of the two sets of subjects, generate third information by performing a decomposition procedure(s) on the first imaging information and the second information, and determine the difference(s) based on the third information.

Abstract: An exemplary system, method and computer-accessible medium for generating a magnetic resonance (MR) image(s) and a positron emission tomography (PET) image(s) of a tissue(s) can be provided, which can include, for example, receiving information related to a combination of MR data and PET data as a single data set, separating the information into at least two dimensions, at least one first of the dimensions corresponding to the MR data and at least one second of the dimensions corresponding to the PET data, and generating the MR image(s) and the PET image(s) based on the separated information.