Patents by Inventor Fernando Goni

Fernando Goni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOTHERAPEUTIC MODULATION OF AMYLOIDOGENIC DISEASE USING NON-FIBRILLOGENIC, NON-AMYLOIDOGENIC POLYMERIZED PROTEINS AND PEPTIDES
    Publication number: 20230130218
    Abstract: The present invention is directed to polymerized products and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Application
    Filed: May 13, 2022
    Publication date: April 27, 2023
    Inventors: Thomas M. WISNIEWSKI, Fernando GONI
  • COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF PRION DISEASE
    Publication number: 20220313802
    Abstract: The present disclosure is directed to a multi-species prion protein or peptide thereof, and vaccine compositions comprising the same that are useful for the vaccination and treatment of mammalian subjects at risk of having or having prion disease. Also disclosed herein are isolated proteins and peptides, polymers, vaccines, animal bait or feed, antibodies, and methods of inhibiting the onset of or treating a prion disease.
    Type: Application
    Filed: May 11, 2020
    Publication date: October 6, 2022
    Inventors: Fernando GONI, Thomas WISNIEWSKI, Lucia YIM, Jose Alejandro CHABALGOITY, Analia ELISEI
  • Immunotherapeutic modulation of amyloidogenic disease using non-fibrillogenic, non-amyloidogenic polymerized proteins and peptides
    Patent number: 11332506
    Abstract: The present invention is directed to polymerized products and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: May 17, 2022
    Assignee: NEW YORK UNIVERSITY
    Inventors: Thomas M. Wisniewski, Fernando Goni
  • SPECIFIC MURINE AND HUMANIZED MONOCLONAL ANTIBODIES DETECTING PATHOLOGY ASSOCIATED SECONDARY STRUCTURE CHANGES IN PROTEINS AND PEPTIDES
    Publication number: 20210324110
    Abstract: The present invention relates to antibodies and binding fragments thereof that bind the ?-sheet secondary structure of a pathological monomeric or oligomeric non-fibrillar proteins without binding to the non-toxic, non-pathological forms of these proteins or peptides. These antibodies and binding fragments thereof are suitable for the diagnosis, prevention, and treatment of protein conformational disorders including all amyloid diseases.
    Type: Application
    Filed: November 13, 2020
    Publication date: October 21, 2021
    Inventors: Thomas M. WISNIEWSKI, Fernando GONI
  • Specific murine and humanized monoclonal antibodies detecting pathology associated secondary structure changes in proteins and peptides
    Patent number: 10870709
    Abstract: The present invention relates to antibodies and binding fragments thereof that bind the ?-sheet secondary structure of a pathological monomeric or oligomeric non-fibrillar proteins without binding to the non-toxic, non-pathological forms of these proteins or peptides These antibodies and binding fragments thereof are suitable for the diagnosis, prevention, and treatment of protein conformational disorders including all amyloid diseases.
    Type: Grant
    Filed: July 22, 2017
    Date of Patent: December 22, 2020
    Assignee: NEW YORK UNIVERSITY
    Inventors: Thomas M. Wisniewski, Fernando Goni
  • IMMUNOTHERAPEUTIC MODULATION OF AMYLOIDOGENIC DISEASE USING NON-FIBRILLOGENIC, NON-AMYLOIDOGENIC POLYMERIZED PROTEINS AND PEPTIDES
    Publication number: 20190338004
    Abstract: The present invention is directed to polymerized products and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Application
    Filed: March 22, 2018
    Publication date: November 7, 2019
    Inventors: Thomas M. Wisniewski, Fernando Goni
  • SPECIFIC MURINE AND HUMANIZED MONOCLONAL ANTIBODIES DETECTING PATHOLOGY ASSOCIATED SECONDARY STRUCTURE CHANGES IN PROTEINS AND PEPTIDES
    Publication number: 20190256612
    Abstract: The present invention relates to antibodies and binding fragments thereof that bind the ?-sheet secondary structure of a pathological monomeric or oligomeric non-fibrillar proteins without binding to the non-toxic, non-pathological forms of these proteins or peptides These antibodies and binding fragments thereof are suitable for the diagnosis, prevention, and treatment of protein conformational disorders including all amyloid diseases.
    Type: Application
    Filed: July 22, 2017
    Publication date: August 22, 2019
    Inventors: Thomas M. WISNIEWSKI, Fernando GONI
  • Immunotherapy targeting of the shared abnormal conformational state of amyloidogenic peptides/proteins
    Patent number: 10253070
    Abstract: The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: April 9, 2019
    Assignee: New York University
    Inventors: Thomas M. Wisniewski, Fernando Goni
  • IMMUNOTHERAPY TARGETING OF THE SHARED ABNORMAL CONFORMATIONAL STATE OF AMYLOIDOGENIC PEPTIDES/PROTEINS
    Publication number: 20180305407
    Abstract: The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Application
    Filed: December 4, 2017
    Publication date: October 25, 2018
    Inventors: Thomas M. WISNIEWSKI, Fernando GONI
  • Immunotherapeutic modulation of amyloidogenic disease using non-fibrillogenic, non-amyloidogenic polymerized proteins and peptides
    Patent number: 9926353
    Abstract: The present invention is directed to polymerized products and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: March 27, 2018
    Assignee: New York University
    Inventors: Thomas M. Wisniewski, Fernando Goni
  • Immunotherapy targeting of the shared abnormal conformational state of amyloidogenic peptides/proteins
    Patent number: 9834582
    Abstract: The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: December 5, 2017
    Assignee: New York University
    Inventors: Thomas M. Wisniewski, Fernando Goni
  • Method for treating amyloid disease
    Patent number: 9770496
    Abstract: The invention relates to methods for treating human amyloid disease by administration of modified A? peptide immunogens.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: September 26, 2017
    Assignee: New York University
    Inventors: Thomas Wisniewski, Fernando Goni
  • METHOD FOR TREATING AMYLOID DISEASE
    Publication number: 20160303208
    Abstract: The invention relates to methods for treating human amyloid disease by administration of modified A? peptide immunogens.
    Type: Application
    Filed: March 21, 2016
    Publication date: October 20, 2016
    Applicant: NEW YORK UNIVERSITY
    Inventors: Thomas WISNIEWSKI, Fernando GONI
  • Method for treating amyloid disease
    Patent number: 9295719
    Abstract: The invention relates to methods for treating human amyloid disease by administration of modified A? peptide immunogens.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: March 29, 2016
    Assignee: NEW YORK UNIVERSITY
    Inventors: Thomas Wisniewski, Fernando Goni
  • Method for Treating Amyloid Disease
    Publication number: 20150165005
    Abstract: The invention relates to methods for treating human amyloid disease by administration of modified A? peptide immunogens.
    Type: Application
    Filed: December 3, 2014
    Publication date: June 18, 2015
    Applicant: NEW YORK UNIVERSITY
    Inventors: Thomas WISNIEWSKI, Fernando GONI
  • IMMUNOTHERAPY TARGETING OF THE SHARED ABNORMAL CONFORMATIONAL STATE OF AMYLOIDOGENIC PEPTIDES/PROTEINS
    Publication number: 20150147334
    Abstract: The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Application
    Filed: February 6, 2015
    Publication date: May 28, 2015
    Applicant: NEW YORK UNIVERSITY
    Inventors: Thomas M. Wisniewski, Fernando Goni
  • Immunotherapy targeting of the shared abnormal conformational state of amyloidogenic peptides/proteins
    Patent number: 8951519
    Abstract: The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: February 10, 2015
    Assignee: New York University
    Inventors: Thomas M. Wisniewski, Fernando Goni
  • Immunotherapy targeting of the shared abnormal conformational state of amyloidogenic peptides/proteins
    Patent number: 8409584
    Abstract: The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Grant
    Filed: May 5, 2010
    Date of Patent: April 2, 2013
    Assignee: New York University
    Inventors: Thomas M. Wisniewski, Fernando Goni
  • IMMUNOTHERAPEUTIC MODULATION OF AMYLOIDOGENIC DISEASE USING NON-FIBRILLOGENIC, NON-AMYLOIDOGENIC POLYMERIZED PROTEINS AND PEPTIDES
    Publication number: 20130022544
    Abstract: The present invention is directed to polymerized products and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Application
    Filed: July 16, 2012
    Publication date: January 24, 2013
    Applicant: NEW YORK UNIVERSITY
    Inventors: Thomas M. Wisniewski, Fernando Goni
  • IMMUNOTHERAPY TARGETING OF THE SHARED ABNORMAL CONFORMATIONAL STATE OF AMYLOIDOGENIC PEPTIDES/PROTEINS
    Publication number: 20100284909
    Abstract: The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
    Type: Application
    Filed: May 5, 2010
    Publication date: November 11, 2010
    Applicant: NEW YORK UNIVERSITY
    Inventors: Thomas M. Wisniewski, Fernando Goni