Abstract: A respiratory monitoring system includes (10) a mechanical ventilator (12) configurable to perform a ventilation mode in that includes an inhalation gas delivery phase and provides extrinsic positive end-expiratory pressure (PEEP) at a PEEP level during an exhalation phase. A breathing tubing circuit (26) includes: a patient port (28), a gas inlet line (16) connected to supply gas from the mechanical ventilator to the patient port, a gas flow meter (30) connected to measure gas flow into lungs of the patient, and a pressure sensor (32) connected to measure gas pressure at the patient port. At least one processor (38) is programmed to: compute a proxy pressure comprising an integral of gas flow into the lungs measured by the gas flow meter; and trigger the inhalation gas delivery phase of the ventilation mode when the proxy pressure decreases below a trigger pressure threshold.

Abstract: A ventilator system, comprising: an inhalation pathway comprising an ambient air inlet, a bi-directional emergency valve, and a dynamic blower; and an exhalation pathway comprising a bi-directional exhalation valve and an exhalation port; wherein when a blockage occurs in the inhalation pathway, ambient air can be drawn from the exhalation port and through the bi-directional exhalation valve, and during exhalation exhalant exits the ventilator through the bi-directional exhalation valve and the exhalation port; wherein when a blockage occurs in the exhalation pathway, inhalant is delivered by the dynamic blower, and during exhalation the dynamic blower lowers its speed or stops and the exhalant exits the ventilator through the bi-directional emergency valve, the dynamic blower, and the ambient air inlet.

Abstract: A ventilation device includes a mechanical ventilator (10), respiratory sensors (30, 32) configured to acquire measurements of respiratory variables including at least measurements of airway pressure and airway flow, and an electronic processor (14) programmed to perform a ventilation method including: operating the mechanical ventilator to provide mechanical ventilation controlled using measurements acquired by the respiratory sensors; performing a pause maneuver comprising closing at least one of an inhalation valve (38) and an exhalation valve (40) for a pause interval and estimating a respiratory mechanics index from one or more respiratory system parameters estimated from measurements acquired by the respiratory sensors during or after the pause interval; and triggering a pause maneuver in response to detecting a change in the estimated respiratory mechanics index.

Abstract: A mechanical ventilator (10) is controlled by an electronic processor (14) to provide respiratory support to a patient (12) using a pressure controlled ventilation mode while being monitored by an airway pressure sensor (30) and an airway flow sensor (32). The electronic processor also controls the ventilator to perform a respiratory system measurement process (44) including: controlling the ventilator to provide a pressure controlled breath at a preset pressure (Ppreset) over an extended inspiratory breath interval that is extended by an extension time interval (TIE) beyond end of physiological inspiration; controlling an exhalation valve (40) at least during the extension time interval to maintain airway pressure at the preset pressure (Ppreset). Lung compliance or elastance is determined from airway pressure measurements and airway flow measurements acquired during the extended inspiratory breath interval.

Abstract: A ventilator system, comprising: an inhalation pathway comprising an ambient air inlet, a bi-directional emergency valve, and a dynamic blower; and an exhalation pathway comprising a bi-directional exhalation valve and an exhalation port; wherein when a blockage occurs in the inhalation pathway, ambient air can be drawn from the exhalation port and through the bi-directional exhalation valve, and during exhalation exhalant exits the ventilator through the bi-directional exhalation valve and the exhalation port; wherein when a blockage occurs in the exhalation pathway, inhalant is delivered by the dynamic blower, and during exhalation the dynamic blower lowers its speed or stops and the exhalant exits the ventilator through the bi-directional emergency valve, the dynamic blower, and the ambient air inlet.

Abstract: The system, method and computer-readable storage medium are for detection of ventilator and patient disconnections using patient lung compliance estimated on both inhalation and exhalation phases of a breath. A ventilator breathing system (10) provides breathing gas to a patient, and includes a gas supply (12), a patient tubing circuit (14) coupled to the gas supply, and a gas monitoring system (16, 18) associated with the patient tubing circuit and configured to monitor at least flow and pressure. A control unit (20) is coupled to the monitoring system and configured to determine a patient disconnection from the system by estimating a patient lung compliance ratio based upon determined volumes of gas delivered during the inhalation phase of the breath cycle and exiting during the exhalation phase of the breath cycle, and monitored pressures in the patient tubing circuit during the inhalation and exhalation phases of the breath cycle.

Abstract: A respiratory monitoring system includes (10) a mechanical ventilator (12) configurable to perform a ventilation mode in that includes an inhalation gas delivery phase and provides extrinsic positive end-expiratory pressure (PEEP) at a PEEP level during an exhalation phase. A breathing tubing circuit (26) includes: a patient port (28), a gas inlet line (16) connected to supply gas from the mechanical ventilator to the patient port, a gas flow meter (30) connected to measure gas flow into lungs of the patient, and a pressure sensor (32) connected to measure gas pressure at the patient port. At least one processor (38) is programmed to: compute a proxy pressure comprising an integral of gas flow into the lungs measured by the gas flow meter; and trigger the inhalation gas delivery phase of the ventilation mode when the proxy pressure decreases below a trigger pressure threshold.

Abstract: A ventilation device includes a mechanical ventilator (10), respiratory sensors (30, 32) configured to acquire measurements of respiratory variables including at least measurements of airway pressure and airway flow, and an electronic processor (14) programmed to perform a ventilation method including: operating the mechanical ventilator to provide mechanical ventilation controlled using measurements acquired by the respiratory sensors; performing a pause maneuver comprising closing at least one of an inhalation valve (38) and an exhalation valve (40) for a pause interval and estimating a respiratory mechanics index from one or more respiratory system parameters estimated from measurements acquired by the respiratory sensors during or after the pause interval; and triggering a pause maneuver in response to detecting a change in the estimated respiratory mechanics index.

Abstract: A mechanical ventilator (10) is controlled by an electronic processor (14) to provide respiratory support to a patient (12) using a pressure controlled ventilation mode while being monitored by an airway pressure sensor (30) and an airway flow sensor (32). The electronic processor also controls the ventilator to perform a respiratory system measurement process (44) including: controlling the ventilator to provide a pressure controlled breath at a preset pressure (Ppreset) over an extended inspiratory breath interval that is extended by an extension time interval (TIE) beyond end of physiological inspiration; controlling an exhalation valve (40) at least during the extension time interval to maintain airway pressure at the preset pressure (Ppreset). Lung compliance or elastance is determined from airway pressure measurements and airway flow measurements acquired during the extended inspiratory breath interval.

Abstract: The present invention relates to a method of delivering gas during ventilation of a patient using a system for breath delivery. The method of gas delivery includes real-time compensation of gas compression losses, in the current breath delivery phase, and gas leakage losses. The present invention further relates to a system for breath delivery. Still further, the present invention relates to a computer implemented method adapted of delivering gas during ventilation of a patient using a system for breath delivery.

Abstract: The system, method and computer-readable storage medium are for detection of ventilator and patient disconnections using patient lung compliance estimated on both inhalation and exhalation phases of a breath. A ventilator breathing system (10) provides breathing gas to a patient, and includes a gas supply (12), a patient tubing circuit (14) coupled to the gas supply, and a gas monitoring system (16, 18) associated with the patient tubing circuit and configured to monitor at least flow and pressure. A control unit (20) is coupled to the monitoring system and configured to determine a patient disconnection from the system by estimating a patient lung compliance ratio based upon determined volumes of gas delivered during the inhalation phase of the breath cycle and exiting during the exhalation phase of the breath cycle, and monitored pressures in the patient tubing circuit during the inhalation and exhalation phases of the breath cycle.

Abstract: A system, method and non-transitory computer readable storage medium for retrieving a breathing reference value, assessing a breathing value of a test subject via a ventilator, identifying a difference between the breathing reference value and the breathing value of the test subject and generating a setting adjustment value to adjust a setting on the ventilator based on the identified difference.

Abstract: The present invention relates to a method of delivering gas during ventilation of a patient using a system for breath delivery. The method of gas delivery includes real-time compensation of gas compression losses, in the current breath delivery phase, and gas leakage losses. The present invention further relates to a system for breath delivery. Still further, the present invention relates to a computer implemented method adapted of delivering gas during ventilation of a patient using a system for breath delivery.

Abstract: The elastance and a resistance of a subject being ventilated are determined. The determination of elastance and resistance of the breathing of the subject is made without adjusting the ventilation of the subject to facilitate the determination. That is, the determination of elastance and resistance of the subject is made without manipulating one or more parameters of the ventilation in a manner not dictated by a treatment algorithm that is designed to ventilate the subject effectively and/or comfortably.