Abstract: Techniques for cognitively interpreting comparative statements are provided. A corpus of documents associated with treatment of a first medical disorder is received. Relative efficacies for a plurality of therapies are determined by, for at least a first respective document in the corpus of documents, identifying and extracting, using one or more natural language processing techniques, a conclusion specified within natural language text of the respective document, where the conclusion includes a comparison between two or more therapies of the plurality of therapies, determining a sentiment of the extracted conclusion, with respect to at least one therapy of the plurality of therapies, and identifying one or more cohorts of patients that are associated with the conclusion. A knowledge graph is generated based on the relative efficacies.

Abstract: A method of searching a database of medical research for documentation in support of a specific treatment for a patient, the method including: identifying a medical condition: identifying attributes of the patient; searching the database for treatment regimens for the medical condition; scoring identified treatment regimens based on similarity of the attributes of the patient to cohorts treated with the treatment regimens and outcomes; and providing a recommendation for a treatment regimen for the patient based on the attributes of the patient.

Abstract: Techniques for evaluating dynamically modified plans are provided. A selection of a treatment plan template is received, where the treatment plan template specifies a plurality of treatment stages, where each treatment stage defines a plurality of treatment options. A plurality of modifications to the treatment plan template is generated. It is determined, for each respective modification of the plurality of modifications, whether the respective modification is permissible, based on one or more predefined institutional criteria. Upon determining that a first modification of the plurality of modifications is permissible, a first treatment plan is generated based on the first modification to the treatment plan template. Further, a first predicted efficacy measure is generated for the first treatment plan based on analyzing a knowledge graph. Finally, the first treatment plan is provided, along with at least an indication of the first predicted efficacy measure.

Abstract: Techniques for dynamic visualization of data are provided. A plurality of therapies is received, where each of the plurality of therapies is associated with a respective plurality of guidelines. A guideline tree is generated based on the plurality of therapies, where each leaf node in the guideline tree represents a respective therapy, and where each edge in the guideline tree represents a respective guideline. A visual depiction of the guideline tree is generated. Further, a first plurality of attributes associated with a first patient is received, and a first modified visual depiction of the guideline tree is generated based on the first plurality of attributes.

Abstract: Techniques for identifying missing evidence are provided. A plurality of documents, each comprising digitally encoded natural language text data, is received. The plurality of documents is processed to determine a plurality of pair-wise comparisons between a plurality of therapies, where each of the plurality of pair-wise comparisons indicate a relative efficacy of at least one therapy in the plurality of therapies, as compared to at least one other therapy in the plurality of therapies. A knowledge graph is generated based at least in part on aggregating the plurality of pair-wise comparisons, and the knowledge graph is analyzed to identify one or more knowledge gaps within the knowledge graph. Finally, at least an indication of the identified one or more knowledge gaps is output.

Abstract: According to embodiments of the present invention, medical treatment outcomes are simulated. A system receives a request to determine a medical treatment pertaining to a medical condition of a patient. The request is applied to one or more models, via a processor, to simulate outcomes for a plurality of different medical treatments for the medical condition, wherein the one or more models account for impacts of the plurality of different medical treatments on use of medical treatments awaiting future approval. The medical treatment is determined from the simulated outcomes, via a processor, with a desired level of impact on the medical treatments awaiting future approval based on characteristics of the patient. Methods and computer readable media are also provided herein for simulating medical treatment outcomes.

Abstract: A method, computer program product, and computing system device for receiving, at a computing device, a plurality of candidate therapy options, a corpus of therapy data, and a set of therapy recipient cohorts. At least a portion of therapy data may be filtered from the corpus of therapy data based upon, at least in part, the plurality of candidate therapy options and the set of therapy recipient cohorts. A graph may be generated to include a plurality of nodes representative of the plurality of candidate therapy options and a plurality of connections between the plurality of nodes indicating a sentiment factor with respect to the plurality of candidate therapy options based upon, at least in part, the at least a portion of therapy data filtered from the corpus of therapy data. Using the graph, a ranked list of the plurality of candidate therapy options may be generated.

Abstract: A method, computer system, and a computer program product for a dynamic question and answer (QA) process is provided. The present invention may include receiving an input by a user. The present invention may also include analyzing a user expertise level and an amount of experience based on the received input. The present invention may then include adjusting an expert recommendation to align with the analyzed user expertise level and the amount of experience based on the analyzed user expertise. The present invention may further include providing a plurality of feedback based on the adjusted expert recommendation.