Abstract: Provided here are compositions for a bacterial artificial chromosome-based construct containing a replication-competent recombinant severe acute respiratory syndrome coronavirus-2 genome and methods of making such compositions and uses thereof.

Abstract: A method of generating labeled training images for a machine learning system includes providing a set of labeled images, each of the labeled images in the set of labeled images depicting an instance of a type of object and comprising a label identifying the type of object, providing an unlabeled image including an instance of the object, generating bounding box coordinates for one or more bounding boxes around the instance of the object in the unlabeled image using the labeled images in the set of labeled images as templates, consolidating the one or more bounding boxes into a consolidated bounding box around the instance of the object in the unlabeled image, and labeling the consolidated bounding box according to the type of object to generate a labeled output image including bounding box coordinates of the consolidated bounding box.

Abstract: A system and method for automatically generating organization level ontology for knowledge retrieval, are provided. An input/output unit receives a plurality of documents from document sources and an ontology generation system generates the organization level ontology based on the documents. The ontology generation system extracts one or more nodes and directed relationships from each document and generates an intermediate document ontology for each document. A combination of syntactic, semantic, and pragmatic assessment of intermediate document ontology is performed to assess at least structure and adaptability of the ontology. The ontology generation system further generates a refined document ontology, based on assessment, to satisfy one or more quality metrics. Each of the refined document ontologies is integrated together to generate the organization level ontology.

Abstract: The present invention relates to novel methods and routes of administration of specific bacterial extracts obtainable by alkaline lysis of Gram positive or Gram negative bacterial species and delivery devices for treating and/or preventing asthma, asthma exacerbation, allergic asthma conditions and/or wheezing associated symptoms and/or associated with microbiota related to respiratory disorders in a subject in need thereof comprising administering a therapeutically effective amount of bacterial extract obtainable from Gram positive or Gram negative bacterial species wherein said bacterial extract is obtainable by alkaline lysis.

Abstract: A turbine housing for a radial/mixed flow turbine, the turbine having a rotor comprising a plurality of blades disposed about a hub, the turbine housing comprising: a shroud configured to at least partially enshroud the rotor wherein a clearance is provided between the shroud and blade tips of the plurality of blades, the shroud and the hub defining a main passage of fluid flow in the turbine; and at least one injection opening provided in the shroud, the at least one injection opening configured to allow injection of a secondary flow of fluid into at least the clearance between the shroud and the blade tips.

Abstract: The present invention relates to an antagonist or inhibitor of G protein-coupled receptor 84 (GPR84) for use in the treatment and/or prevention of a patient suffering from, at risk of developing, and/or being diagnosed for endometriosis, as well as methods of screening for such antagonist or inhibitor as well as methods for diagnosis.

Abstract: The present invention relates to a method and system for tracking, issuing, and authenticating gear or articles, such as uniforms, badges, equipment, weapons, etc, for use in law enforcement or other official capacity.

Abstract: An axle assembly having a differential assembly that may include a gear reduction unit, a differential nest, and a coupling. The differential nest may be at least partially received in an inner housing. The inner housing may be rotatable about an axis with respect to an outer housing when the coupling is in a first position. The inner housing may be rotatable about the axis with the outer housing when the coupling is in a second position.

Abstract: An axle assembly having a differential assembly that may include a gear reduction unit, a differential nest, and a coupling. The differential nest may be at least partially received in an inner housing. The inner housing may be rotatable about an axis with respect to an outer housing when the coupling is in a first position. The inner housing may be rotatable about the axis with the outer housing when the coupling is in a second position.

Abstract: The present invention is related to an anaerobic photobioreactor and a method for active biomass cultivation, wastewater treatment, nutrients recovery, energy production and high-value products synthesis. Phototrophic bacteria are cultured in the anaerobic photobioreactor lighted with solar or artificial irradiation where certain light wavelengths are selectively discarded with a light selector installed on the top of the photobioreactor. In this light-based process wastewater treatment and resources recovery, like nutrients and high-value bioproducts (fertilizers, polymers and proteins) present in wastewater are performed simultaneously. Cultured biomass is treated by anaerobic digestion for biofuel production, including optative hydrolytic pre-treatment, and/or valuable bioproducts can be obtained in a downstream process.

Abstract: Curing apparatus, image forming apparatus and articles of manufacture are disclosed. An example curing apparatus includes a curing unit to heat an area adjacent a substrate travel path, the curing unit having a width less than a width of the substrate travel path, and a controller to reciprocate the curing unit within the substrate width.

Abstract: A turbine housing for a radial/mixed flow turbine, the turbine having a rotor comprising a plurality of blades disposed about a hub, the turbine housing comprising: a shroud configured to at least partially enshroud the rotor wherein a clearance is provided between the shroud and blade tips of the plurality of blades, the shroud and the hub defining a main passage of fluid flow in the turbine; and at least one injection opening provided in the shroud, the at least one injection opening configured to allow injection of a secondary flow of fluid into at least the clearance between the shroud and the blade tips.

Abstract: A manufacturing process includes depositing a clad layer having a thickness greater than about 0.5 mm (0.02 in) on a surface of the component by hardfacing, and creating a heat affected zone directly below the clad layer due to the depositing. The heat affected zone may be a region of the component where a lowest hardness is lower than a base hardness of the component below the heat affected zone. The method may also include heat treating the component after the deposition such that the lowest hardness in the heat affected zone is restored to within about 15% of the base hardness of the component.

Abstract: Aspects of the disclosure relate to a method for treating idiopathic pulmonary fibrosis (IPF) in a patient with N-acetylcysteine (NAC) comprising administering NAC to a patient after a sample from the patient has been genotyped and determined to be any one of: a) homozygous or heterozygous for a thymine at the single nucleotide polymorphism rs3750920; b) homozygous or heterozygous for guanine at the single nucleotide polymorphism rs5743894; or c) homozygous or heterozygous for thymine at the single nucleotide polymorphism rs35705950.

Abstract: An enclosure for providing a local convergence point for a fiber optic network may include an enclosure frame and an end panel defining a plurality of ports. The enclosure may include a feeder compartment to receive through at least one of the ports an optical source cable from the network. The enclosure may include a feeder compartment panel pivotally coupled to the feeder compartment and configured to pivot. The enclosure may also include a feeder splice tray removably coupled to the feeder compartment panel and configured to receive one or more optical fibers from the optical source cable. The feeder splice tray may be configured to communicatively couple at least one optical fiber of the optical source cable to at least one distribution fiber configured to facilitate communication with a destination device configured to receive an optical signal from the network.

Abstract: Aspects of the disclosure relate to a method for treating idiopathic pulmonary fibrosis (IPF) in a patient with N-acetylcysteine (NAC) comprising administering NAC to a patient after a sample from the patient has been genotyped and determined to be any one of: a) homozygous or heterozygous for a thymine at the single nucleotide polymorphism rs3750920; b) homozygous or heterozygous for guanine at the single nucleotide polymorphism rs5743894; or c) homozygous or heterozygous for thymine at the single nucleotide polymorphism rs35705950.

Abstract: The present invention relates to a method and system for tracking, issuing, and authenticating gear or articles, such as uniforms, badges, equipment, weapons, etc, for use in law enforcement or other official capacity.

Abstract: An enclosure for providing a local convergence point for a fiber optic network may include an enclosure frame and an end panel defining a plurality of ports. The enclosure may include a feeder compartment to receive through at least one of the ports an optical source cable from the network. The enclosure may include a feeder compartment panel pivotally coupled to the feeder compartment and configured to pivot. The enclosure may also include a feeder splice tray removably coupled to the feeder compartment panel and configured to receive one or more optical fibers from the optical source cable. The feeder splice tray may be configured to communicatively couple at least one optical fiber of the optical source cable to at least one distribution fiber configured to facilitate communication with a destination device configured to receive an optical signal from the network.

Abstract: Curing apparatus, image forming apparatus and articles of manufacture are disclosed. An example curing apparatus includes a curing unit to heat an area adjacent a substrate travel path, the curing unit having a width less than a width of the substrate travel path, and a controller to reciprocate the curing unit within the substrate width.

Abstract: The present invention relates to a pharmaceutical tramadol composition for ophthalmic use. The composition is characterised in that it contains tramadol in a low concentration, specifically between 0.02% and 0.09%, and in that it is highly efficient in the treatment of ocular pain, for example following injuries or ocular surgery, or the ocular pain associated with dry eye syndrome.