Patents by Inventor Fernando Padilla

Fernando Padilla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (AZA)INDAZOLYL-ARYL SULFONAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS
    Publication number: 20220388964
    Abstract: The invention provides (aza)indazolyl-aryl sulfonamide and related compounds, pharmaceutical compositions, and their use in the treatment of medical conditions, such as cancer, and in inhibiting GCN2 activity.
    Type: Application
    Filed: April 13, 2020
    Publication date: December 8, 2022
    Inventors: Savithri Ramurthy, Mark J. Mulvihill, Bradley Sherborne, Eric Talbot, Chris Thomson, Thomas Daniel Aicher, Fernando Padilla, Clarke B. Taylor, Peter L. Toogood
  • ALKYNYL QUINAZOLINE COMPOUNDS
    Publication number: 20220298120
    Abstract: The present disclosure relates to compounds of Formula (I?): and pharmaceutically acceptable salts and stereoisomers thereof. The present disclosure also relates to methods of preparation these compounds, compositions comprising these compounds, and methods of using them in the prevention or treatment of abnormal cell growth in mammals, especially humans.
    Type: Application
    Filed: August 14, 2020
    Publication date: September 22, 2022
    Inventors: Matthew C. LUCAS, Fernando PADILLA, Alexander FLOHR, Luca ARISTA, Elizabeth BUCK
  • Indazolyl-1,2,4-thiadiazolamines and related compounds for inhibition of Rho-associated protein kinase and the treatment of disease
    Patent number: 10556898
    Abstract: The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting Rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an N-(3-(5-((1H-indazol-5-yl)amino)-1,2,4-thiadiazol-3-yl)phenyl)-heteroaryl-carboxamide compound.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: February 11, 2020
    Assignee: Lycera Corporation
    Inventors: Thomas D. Aicher, Fernando Padilla, Donald J. Skalitzky, Peter L. Toogood, Chad A. VanHuis
  • INDAZOLYL-1,2,4-THIADIAZOLAMINES AND RELATED COMPOUNDS FOR INHIBITION OF RHO-ASSOCIATED PROTEIN KINASE AND THE TREATMENT OF DISEASE
    Publication number: 20190276447
    Abstract: The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting Rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an N-(3-(5-((1H-indazol-5-yl)amino)-1,2,4-thiadiazol-3-yl)phenyl)-heteroaryl-carboxamide compound.
    Type: Application
    Filed: February 14, 2019
    Publication date: September 12, 2019
    Inventors: Thomas D. Aicher, Fernando Padilla, Donald J. Skalitzky, Peter L. Toogood, Chad A. VanHuis
  • Inhibitors of SYK
    Patent number: 10112928
    Abstract: The present invention relates to the use of novel compounds of formula I: wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: October 30, 2018
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Niala Bhagirath, Joshua Kennedy-Smith, Nam T. Le, Matthew C. Lucas, Fernando Padilla, Michael Soth
  • Indazolyl thiadiazolamines and related compounds for inhibition of Rho-associated protein kinase and the treatment of disease
    Patent number: 10112935
    Abstract: The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting Rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an N-(5-[5-[(1H4ndazol-5-yl)amino]-1,3,4-thiadiazol-2-yl]pyridin-3-yl)acetamide compound.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: October 30, 2018
    Assignee: Lycera Corporation
    Inventors: Thomas Daniel Aicher, Fernando Padilla, Peter L. Toogood, Shoujun Chen
  • 1 H-pyrazole and 4,5-disubstituted thiazole inhibitors of SYK
    Patent number: 9988378
    Abstract: The present invention relates to the use of novel compounds of formula (I), wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Grant
    Filed: October 23, 2013
    Date of Patent: June 5, 2018
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Niala Bhagirath, Joshua Kennedy-Smith, Matthew C. Lucas, Fernando Padilla
  • Devices and methods for printing on boards
    Patent number: 9956788
    Abstract: A device of the present disclosure has a board reception plate coupled on a first side to a first side plate and coupled on a second side to a second side plate, and the board reception plate is adapted for supporting a board. The apparatus further has a first spring-loaded sliding bar coupled to the first side plate that has a first channel for receiving a first edge of the board and a second spring-loaded sliding bar coupled to the second side plate that has a second channel for receiving a second edge of the board.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: May 1, 2018
    Assignee: Stitch City Industries
    Inventor: Fernando Padilla
  • INDAZOLYL THIADIAZOLAMINES AND RELATED COMPOUNDS FOR INHIBITION OF RHO-ASSOCIATED PROTEIN KINASE AND THE TREATMENT OF DISEASE
    Publication number: 20180093978
    Abstract: The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting Rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an N-(5-[5-[(1H4ndazol-5-yl)amino]-1,3,4-thiadiazol-2-yl]pyridin-3-yl)acetamide compound.
    Type: Application
    Filed: February 26, 2016
    Publication date: April 5, 2018
    Inventors: Thomas Daniel Aicher, Fernando Padilla, Peter L. Toogood, Shoujun Chen
  • Persona engine
    Patent number: 9754268
    Abstract: In one embodiment at least one user profile of a user may be obtained. Information may be provided to the user by one or more personalization engines based, at least in part, upon the at least one user profile. Each of the one or more personalization engines may be configured to operate according to a different one of a plurality of personas.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: September 5, 2017
    Assignee: Yahoo Holdings, Inc.
    Inventors: Steven Andrew McClelland, Michael Metcalf, Fernando Padilla, Sarah Jean Sosiak
  • Thienopyrimidine compounds
    Patent number: 9701691
    Abstract: The present invention relates to the use of novel compounds of Formula I: wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: July 11, 2017
    Assignee: Hoffman-La Roche Inc.
    Inventors: Shaoqing Chen, Johannes Cornelius Hermann, Nam T. Le, Matthew C. Lucas, Fernando Padilla
  • Devices and Methods for Printing on Boards
    Publication number: 20170144452
    Abstract: A device of the present disclosure has a board reception plate coupled on a first side to a first side plate and coupled on a second side to a second side plate, and the board reception plate is adapted for supporting a board. The apparatus further has a first spring-loaded sliding bar coupled to the first side plate that has a first channel for receiving a first edge of the board and a second spring-loaded sliding bar coupled to the second side plate that has a second channel for receiving a second edge of the board.
    Type: Application
    Filed: November 24, 2015
    Publication date: May 25, 2017
    Inventor: Fernando Padilla
  • System and method for printing customized graphics on footwear and other articles of clothing
    Patent number: 9635907
    Abstract: A shoe platen to securely hold a shoe so that graphics, including custom graphics, can be printed on the shoe automatically. The platen comprises a shoe plate 102 configured to receive shoes such as high-top shoes or low top shoes. Adjusters 104, 106 can also be used to accommodate shoes of various styles and sizes.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: May 2, 2017
    Assignee: Pics on Kicks, LLC
    Inventors: Nick Romero, Fernando Padilla
  • Pyrrolo[2,3-B]pyrazines as SYK inhibitors
    Patent number: 9334278
    Abstract: The present invention relates to the use of novel pyrrolo[2,3-b]]pyrazines wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: May 10, 2016
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Johannes Cornelius Hermann, Joshua Kennedy-Smith, Matthew C. Lucas, Fernando Padilla, Ryan Craig Schoenfeld, Peter Michael Wovkulich
  • Imidazopyridazine compounds
    Patent number: 9169259
    Abstract: The present invention relates to the use of novel compounds of formula I: wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: October 27, 2015
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Johannes Cornelius Hermann, Andreas Kuglstatter, Matthew C. Lucas, Fernando Padilla, Jutta Wanner, Xiaohu Zhang
  • INHIBITORS OF SYK
    Publication number: 20150284367
    Abstract: The present invention relates to the use of novel compounds of formula I: wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Application
    Filed: October 15, 2013
    Publication date: October 8, 2015
    Inventors: Niala Bhagirath, Joshua Kennedy-Smith, Nam T. Le, Matthew C. Lucas, Fernando Padilla, Michael Soth
  • 1 H-PYRAZOLE AND 4,5-DISUBSTITUTED THIAZOLE INHIBITORS OF SYK
    Publication number: 20150266874
    Abstract: The present invention relates to the use of novel compounds of formula (I), wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Application
    Filed: October 23, 2013
    Publication date: September 24, 2015
    Inventors: Niala Bhagirath, Joshua Kennedy-Smith, Matthew C. Lucas, Fernando Padilla
  • PYRROLO[2,3-B]PYRAZINES AS SYK INHIBITORS
    Publication number: 20150218170
    Abstract: The present invention relates to the use of novel pyrrolo[2,3-b]]pyrazines wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Application
    Filed: August 19, 2013
    Publication date: August 6, 2015
    Inventors: Johannes Cornelius Hermann, Joshua Kennedy-Smith, Matthew C. Lucas, Fernando Padilla, Ryan Craig Schoenfeld, Peter Michael Wovkulich
  • Thiazolopyrimidine compounds
    Patent number: 8921383
    Abstract: The present invention relates to the use of novel thiazolopyrimidine derivatives of formula I: wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: December 30, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Johannes Cornelius Hermann, Lee Edwin Lowrie, Jr., Matthew C. Lucas, Kin-Chun Thomas Luk, Fernando Padilla, Jutta Wanner, Wenwei Xie, Xiaohu Zhang
  • Pyridazine amide compounds useful as SYK inhibitors
    Patent number: 8901124
    Abstract: The present invention relates to the use of novel triazolopyridine derivatives of formula I: wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: December 2, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Johannes Cornelius Hermann, Joshua Kennedy-Smith, Matthew C. Lucas, Fernando Padilla, Michael Soth