Patents by Inventor Fernando R. Goni

Fernando R. Goni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mucosal immunization to prevent prion infection
    Patent number: 9700607
    Abstract: Vaccines against prion disease eliciting a humoral immune response when administered mucosally are described. The vaccines comprise a prion protein, a prion protein fragment, or a non-amyloidogenic prion protein homolog and an adjuvant suitable for inducing a humoral immune response after mucosal administration. Suitable adjuvants include cholera toxin subunit B, heat-labile enterotoxin and aluminum hydroxide. Alternatively, the vaccine comprises a vector encoding a prion protein, fragment, or homolog in an attenuated Salmonella host. The vaccines can be used to prevent or treat prion disease in humans and other mammals.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: July 11, 2017
    Assignee: New York University
    Inventors: Thomas Wisniewski, Einar M. Sigurdsson, Jose Alejandro Chabalgoity, Fernando R. Goni, Blas Frangione
  • MUCOSAL IMMUNIZATION TO PREVENT PRION INFECTION
    Publication number: 20150044243
    Abstract: Vaccines against prion disease eliciting a humoral immune response when administered mucosally are described. The vaccines comprise a prion protein, a prion protein fragment, or a non-amyloidogenic prion protein homolog and an adjuvant suitable for inducing a humoral immune response after mucosal administration. Suitable adjuvants include cholera toxin subunit B, heat-labile enterotoxin and aluminum hydroxide. Alternatively, the vaccine comprises a vector encoding a prion protein, fragment, or homolog in an attenuated Salmonella host. The vaccines can be used to prevent or treat prion disease in humans and other mammals.
    Type: Application
    Filed: February 6, 2014
    Publication date: February 12, 2015
    Applicant: NEW YORK UNIVERSITY
    Inventors: Thomas Wisniewski, Einar M. Sigurdsson, Jose Alejandro Chabalgoity, Fernando R. Goni, Blas Frangione
  • Method for treating amyloid disease
    Patent number: 8906382
    Abstract: The invention relates to methods for treating human amyloid disease by administration of modified A? peptide immunogens.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: December 9, 2014
    Assignee: New York University
    Inventors: Thomas Wisniewski, Fernando R. Goni
  • Mucosal immunization to prevent prion infection
    Patent number: 8685718
    Abstract: Vaccines against prion disease eliciting a humoral immune response when administered mucosally are described. The vaccines comprise a prion protein, a prion protein fragment, or a non-amyloidogenic prion protein homolog and an adjuvant suitable for inducing a humoral immune response after mucosal administration. Suitable adjuvants include cholera toxin subunit B, heat-labile enterotoxin and aluminum hydroxide. Alternatively, the vaccine comprises a vector encoding a prion protein, fragment, or homolog in an attenuated Salmonella host. The vaccines can be used to prevent or treat prion disease in humans and other mammals.
    Type: Grant
    Filed: May 20, 2004
    Date of Patent: April 1, 2014
    Assignee: New York University
    Inventors: Thomas Wisniewski, Einar M. Sigurdsson, Jose Alejandro Chabalgoity, Fernando R. Goni, Blas Frangione
  • METHOD FOR TREATING AMYLOID DISEASE
    Publication number: 20130022630
    Abstract: The invention relates to methods for treating human amyloid disease by administration of modified A? peptide immunogens.
    Type: Application
    Filed: July 19, 2012
    Publication date: January 24, 2013
    Inventors: Thomas Wisniewski, Fernando R. Goni