Patents by Inventor Fernando Reyes Benítez
Fernando Reyes Benítez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10414745Abstract: The present invention relates to compounds of general formula (I) wherein R1-R8 take various meanings, pharmaceutical compositions containing them and their use in medicine, particularly for the treatment and/or prophylaxis of cancer.Type: GrantFiled: April 29, 2016Date of Patent: September 17, 2019Assignee: FUNDACIÓN MEDINA. CENTRO DE EXCELENCIA EN INVESTIGACIÓN DE MEDICAMENTOS INNOVADORES EN ANDALUCÍAInventors: Nuria De Pedro Montejo, Victor Gonzalez Menendez, Gloria Crespo Sueiro, Ignacio Perez-Victoria Moreno De Barreda, Bastien Cautain, Maria Francisca Vicente Perez, Jose Fernando Reyes Benitez, Olga Genilloud Rodriguez, Carmen Grinan Lison, Juan Antonio Marchal Corrales
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Publication number: 20180148427Abstract: The present invention relates to compounds of general formula (I) wherein R1-R8 take various meanings, pharmaceutical compositions containing them and their use in medicine, particularly for the treatment and/or prophylaxis of cancer.Type: ApplicationFiled: April 29, 2016Publication date: May 31, 2018Applicant: FUNDACION MEDINA CENTRO DE EXCELENCIA DE MEDICAMENTOS INNOVAInventors: Nuria DE PEDRO MONTEJO, Victor GONZALEZ MENENDEZ, Gloria CRESPO SUEIRO, Ignacio PEREZ-VICTORIA MORENO DE BARREDA, Bastien CAUTAIN, Maria Francisca VICENTE PEREZ, Jose Fernando REYES BENITEZ, Olga GENILLOUD RODRIGUEZ, Carmen GRINAN LISON, Juan Antonio MARCHAL CORRALES
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Publication number: 20160185717Abstract: The present invention relates to compounds of general formula (I) wherein R1, R2, R3 and take various meanings, pharmaceutical compositions containing them and their use in medicine, particularly for the treatment and/or prophylaxis of a bacterial infection disease.Type: ApplicationFiled: June 30, 2014Publication date: June 30, 2016Inventors: Olga GENILLOUD RODRÍGUEZ, José Rubén TORMO BELTRÁN, José Fernando REYES BENÍTEZ, Noureddine EL AOUAD, Maria Francisca VICENTE PEREZ, Mercedes DE LA CRUZ MORENO, Gerald Fremont BILLS, Victor Manuel GONZÁLEZ MENÉNDEZ, Maria Cåndida TEIRO DE AGUIAR
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Patent number: 8962602Abstract: A compound of general formula (I), wherein R1-R17 and the - - - - - - line take various meanings for use in the treatment of cancer.Type: GrantFiled: April 26, 2011Date of Patent: February 24, 2015Assignee: Pharma Mar, S.A.Inventors: Rogelio Fernández Rodríguez, José Fernando Reyes Benítez, Andrés Francesch Solloso, María del Carmen Cuevas Marchante
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Patent number: 8501968Abstract: Antitumoral compounds obtained from a porifera, of the family Raspailiidae, genus Lithoplocamia, species lithistoides, and derivatives thereof are provided.Type: GrantFiled: June 29, 2011Date of Patent: August 6, 2013Assignee: PharmaMar, S.A.Inventors: Ma Jesús Martin López, Laura Coello Molinero, José Fernando Reyes Benítez, Alberto Rodríguez Vicente, María Garranzo García-Ibarrola, Carmen Murcia Pérez, Andrés Francesch Solloso, Francisco Sánchez Sancho, Maria del Carmen Cuevas Marchante, Rogelio Fernández Rodríguez
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Publication number: 20130040921Abstract: A compound of general formula (I), wherein R1-R17 and the ------ line take various meanings for use in the treatment of cancer.Type: ApplicationFiled: April 26, 2011Publication date: February 14, 2013Applicant: PHARMA MAR, S.A.Inventors: Rogelio Fernández Rodríguez, José Fernando Reyes Benítez, Andrés Francesch Solloso, María del Carmen Cuevas Marchante
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Patent number: 8324406Abstract: Antitumoral compounds obtained from a porifera, of the family Raspailiidae, genus Lithoplocamia, species lithistoides, and derivatives thereof are provided.Type: GrantFiled: June 15, 2007Date of Patent: December 4, 2012Assignee: Pharma Mar, S.A.Inventors: Ma Jesús Martín López, Laura Coello Molinero, José Fernando Reyes Benítez, Alberto Rodríguez Vicente, María Garranzo García-Ibarrola, Carmen Murcia Pérez, Andrés Francesch Solloso, Francisco Sánchez Sancho, María del Carmen Cuevas Marchante, Rogelio Fernández Rodríguez
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Publication number: 20120190870Abstract: Antitumoral compounds obtained from a porifera, of the family Raspailiidae, genus Lithoplocamia, species lithistoides, and derivatives thereof are provided.Type: ApplicationFiled: June 29, 2011Publication date: July 26, 2012Inventors: Ma Jesús Martín López, Laura Coello Molinero, José Fernando Reyes Benítez, Alberto Rodríguez Vicente, María Garranzo García- Ibarrola, Carmen Murcia Pérez, Andrés Francesch Solloso, Francisco Sánchez Sancho, María del Carmen Cuevas Marchante, Rogelio Fernández Rodríguez
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Publication number: 20110237520Abstract: Compounds of general formula I: wherein R1-R15 and n take permitted meanings for use in the treatment of cancer.Type: ApplicationFiled: December 18, 2009Publication date: September 29, 2011Applicant: Pharma Mar, SAInventors: Laura Coello Molinero, Rogelio Fernández Rodriguez, José Fernando Reyes Benitez, Andrés Francesch Solloso, Maria del Carmen Cuevas Marchante
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Publication number: 20110118343Abstract: Antitumoral compounds of general formula I: wherein R1-R14 and the lines take permitted meanings for use in the treatment of cancer.Type: ApplicationFiled: July 2, 2009Publication date: May 19, 2011Applicant: Pharma Mar, S. A.Inventors: José Fernando Reyes Benítez, Gloria Crespo Sueiro, Rogelio Fernández Rodríguez, Andrés Francesch Solloso, María del Carmen Cuevas Marchante
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Publication number: 20110105409Abstract: Anticancer compounds of general formula I: wherein R1-R11 take permitted meanings for use in the treatment of cancer.Type: ApplicationFiled: July 16, 2009Publication date: May 5, 2011Applicant: PHARMA MAR, S.A.Inventors: Raquel Rodríguez Acebes, Rogelio Fernández Rodríguez, José Fernando Reyes Benítez, Ma Jesús Martín López, Isabel Marco Martínez, Isabel Digón Juárez, Maria del Carmen Cuevas Marchante, Andrés Francesch Solloso
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Publication number: 20100216817Abstract: Antitumoral compounds of the formula (I) wherein X is O, S, or NRa, obtained from a maze coral of the family Meandrinidae, genus Meandrina, species meandrites, or derivatives thereof are useful as antitumoral agents.Type: ApplicationFiled: May 3, 2006Publication date: August 26, 2010Applicant: Pharma Mar SAInventors: José Fernando Reyes Benitez, Maria del Carmen Cuevas Marchante, David Montalvo Lobo, Maria-Jesús Martin López, Maria Cristina Mateo Urbano, Andrés Francesch Solloso
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Patent number: 7723068Abstract: A gene cluster is disclosed having open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule. In addition, the present disclosure is directed to a nucleic acid sequence, suitably an isolated nucleic acid sequence, which includes or comprises at least SEQ ID NO:1, variants or portions thereof, or at least one of the sacA, sacB, sacC, sacC, sacD, sacE, sacF, sacG, sacH, sacH, saI, sacJ, orf1, orf2, orf3 or orf4 genes, including variants or portions.Type: GrantFiled: December 19, 2003Date of Patent: May 25, 2010Assignee: PharmaMar, S.A.Inventors: Ana Velasco Iglesias, Fernando de la Calle, Tomás Aparicio Pérez, Carmen Schleissner Sánchez, Paloma Acebo Páis, Pilar Rodríguez Ramos, Fernando Reyes Benítez, Rubén Henrìquez Peláez
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Publication number: 20100048690Abstract: Antitumoral compounds obtained from a porifera, of the family Raspailiidae, genus Lithoplocamia, species lithistoides, and derivatives thereof are provided.Type: ApplicationFiled: June 15, 2007Publication date: February 25, 2010Applicant: PHARMA MAR, S.A.Inventors: Ma Jesus Martin Lopez, Laura Coello Molinero, Jose Fernando Reyes Benitez, Alberto Rodriguez Vicente, Maria Garranzo Garcia-Ibarrola, Carmen Murcia Perez, Andres Francesch Solloso, Francisco Sanchez Sancho, Maria del Carmen Cuevas Marchante, Rogelio Fernandez Rodriguez
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Publication number: 20100048596Abstract: Antitumoural compounds of general formula (I); wherein Ar is an heterocyclic group of formula (a) and R1, R2, R3, R4, R5, R6, R7, n and the dotted line take permitted meanings can be obtained from a tunicate of the family Polyclinidae, genus Aplidium, species cyaneum, and the invention further provides derivatives thereof.Type: ApplicationFiled: November 13, 2006Publication date: February 25, 2010Applicant: Pharma Mar, S.A.Inventors: Jose Fernando Reyes Benitez, Andrés Francesch Solloso, Carmen Cuevas Marchante, Marta Altuna Urquijo, Daniel Pla Queral, Mercedes Alvarez Domingo, Fernando Albericio Palomera
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Publication number: 20090186938Abstract: Antitumoral compounds obtained from a porifera, of the family Raspailiidae, genus Lithoplocamia, species lithistoides, and derivatives thereof are provided.Type: ApplicationFiled: June 15, 2007Publication date: July 23, 2009Applicant: PHARMA MAR, S.A.Inventors: Ma Jesus Martin Lopez, Laura Coello Molinero, Jose Fernando Reyes Benitez, Alberto Rodriguez Vicente, Maria Garranzo Garcia-Ibarrola, Carmen Murcia Perez, Andres Francesch Solloso, Francisco Sanchez Sancho, Maria del Carmen Cuevas Marchante, Rogelio Fernandez Rodriguez
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Publication number: 20090124647Abstract: Antitumoural compounds of general formula (I); wherein Ar is an heterocyclic group of formula (a) and R1, R2, R3, R4, R5, R6, R7, n and the dotted line take permitted meanings can be obtained from a tunicate of the family Polyclinidae, genus Aplidium, species cyaneum, and the invention further provides derivatives thereof.Type: ApplicationFiled: November 13, 2006Publication date: May 14, 2009Applicant: PHARMA MAR, S.A.Inventors: Jose Fernando Reyes Benitez, Andres Francesch Solloso, Carmen Cuevas Marchante, Marta Altuna Urquijo, Daniel Pla Queral, Mercedes Alvarez Domingo, Fernando Albericio Palomera
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Publication number: 20090030068Abstract: The invention relates to novel antitumor compounds of general formula as well as their corresponding pharmaceutically acceptable salts, derivatives, prodrugs and stereoisomers. These compounds can be obtained by isolating a sponge from family Theonellidae, genus Theonella and species swinhoei, and forming derivatives from the isolated compounds. These compounds have cytotoxic activity and can be used for the treatment of the cancer.Type: ApplicationFiled: December 14, 2006Publication date: January 29, 2009Applicant: PHARMA MAR, S.A.Inventors: Ma Jesus Martin Lopez, Jose Fernando Reyes Benitez, Rogelio Fernandez Rodriguez, Andres Francesch Solloso, Maria del Carmen Cuevas Marchante, Laura Coello Molinero
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Publication number: 20080234363Abstract: Compounds of general formula (I), wherein R1, R2, R3, R4, R5, R6 and Y are as defined, and X group is O, S(O)m or NR; are of use in the treatment of cancer.Type: ApplicationFiled: August 1, 2006Publication date: September 25, 2008Applicant: PHARMA MAR, S.A.Inventors: Jose Fernando Reyes Benitez, Jose Antonio Jimenez Guerrero, Andres Manuel Francesch Solloso, Maria Del Carmen Cuev As Marchante
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Publication number: 20080182302Abstract: A gene cluster has open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule.Type: ApplicationFiled: September 22, 2005Publication date: July 31, 2008Applicant: Pharma Mar, S.A.Inventors: Ana Velasco Iglesias, Fernando de la Calle, Tomás Aparicio Pérez, Carmen Schleissner Sánchez, Paloma Acebo Páis, Pilar Rodriguez Ramos, Fernando Reyes Benitez, Ruben Henriquez Pelaez