Abstract: The present invention relates to the field of immunogenic compositions and the use of such compositions in medicine. More particularly, it relates to immunogenic compositions comprising an immunogenic polypeptide from non-typeable Haemophilus influenzae, a PE-PilA fusion protein, and optionally an immunogenic polypeptide of UspA2 from Moraxella catarrhalis, for use in subjects having chronic obstructive pulmonary disease (COPD), in particular for reducing the frequency of severe exacerbations (i.e. severe AECOPDs).

Abstract: A system, method, and apparatus for retrofitting a fluorescent light fixture accommodating an LED-based lighting system. A track is electrically connected to the driver module. The track includes at least one electronic conductor that is connected along the length of the track. At least one track adapter may connect to the track, and the track adapter includes a locking mechanism that allows the track adapter to connect to the track at any location along the track and the track may be removed. The locking mechanism may permit the track adapter to be removable. At least one light engine module can connect to the track and may also be removable.

Abstract: A system, method, and apparatus for retrofitting a fluorescent light fixture accommodating an LED-based lighting system. A track is electrically connected to the driver module. The track includes at least one electronic conductor that is connected along the length of the track. At least one track adapter may connect to the track, and the track adapter includes a locking mechanism that allows the track adapter to connect to the track at any location along the track and the track may be removed. The locking mechanism may permit the track adapter to be removable. At least one light engine module can connect to the track and may also be removable.

Abstract: A system, method, and apparatus for retrofitting a fluorescent light fixture accommodating an LED-based lighting system. A track is electrically connected to the driver module. The track includes at least one electronic conductor that is connected along the length of the track. At least one track adapter may connect to the track, and the track adapter includes a locking mechanism that allows the track adapter to connect to the track at any location along the track and the track may be removed. The locking mechanism may permit the track adapter to be removable. At least one light engine module can connect to the track and may also be removable.

Abstract: A system, method, and apparatus for retrofitting a fluorescent light fixture accommodating an LED-based lighting system. A track is electrically connected to the driver module. The track includes at least one electronic conductor that is connected along the length of the track. At least one track adapter may connect to the track, and the track adapter includes a locking mechanism that allows the track adapter to connect to the track at any location along the track and the track may be removed. The locking mechanism may permit the track adapter to be removable. At least one light engine module can connect to the track and may also be removable.

Abstract: A system, method, and apparatus for retrofitting a fluorescent light fixture accommodating an LED-based lighting system. A track is electrically connected to the driver module. The track includes at least one electronic conductor that is connected along the length of the track. At least one track adapter may connect to the track, and the track adapter includes a locking mechanism that allows the track adapter to connect to the track at any location along the track and the track may be removed. The locking mechanism may permit the track adapter to be removable. At least one light engine module can connect to the track and may also be removable.

Abstract: A system, method, and apparatus for retrofitting a fluorescent light fixture accommodating an LED-based lighting system. A track is electrically connected to the driver module. The track includes at least one electronic conductor that is connected along the length of the track. At least one track adapter may connect to the track, and the track adapter includes a locking mechanism that allows the track adapter to connect to the track at any location along the track and the track may be removed. The locking mechanism may permit the track adapter to be removable. At least one light engine module can connect to the track and may also be removable.

Abstract: A lamp having a candle-like appearance and using one or more light-emitting diodes (LEDs) as its light source is presented. The candle-like appearance arises because light is emitted from only a small volume at or near the center of the bulb. The heat sink and control electronics are located outside the bulb of the lamp. Inside the bulb is a set of secondary optics that guide the light from one or more LEDs to an emission point at a prescribed location in the interior of the bulb. The secondary optics include a light pipe that guides light away from the LED chip, and a volume scattering element that receives the light from the light pipe and scatters it into various directions. The volume scattering element is made from a transparent base material, and includes transparent particles of a predetermined size and refractive index.

Abstract: Methods for characterisation of patients as responders or non-responders to therapy based on differential expression of one or more genes are provided. Gene expression profiles, microarrays comprising nucleic acid sequences representing gene expression profiles, and new diagnostic kits and methods of treatment are also provided. The kits and methods relate to the treatment of specific populations of, for example, cancer patients, as characterised by their gene expression profile, suffering from MAGE expressing tumours.

Abstract: An Internet-based product brand marketing communication network allowing members of a consumer product brand management team to communicate directly with consumers present at HTML-encoded pages of an electronic commerce (EC) enabled Web-site along fabric of the World Wide Web (WWW), using programmable Multi-Mode Virtual Kiosks (MMVKs) driven by server-side components and managed by product brand management team members and/or authorized parties. When a consumer's Web browser encounters an MMVK tag along the WWW, the MMVK is generated and automatically plays through its display modes, inviting and allowing the consumer to review and interact with advertising spots, promotional spots, and brand information resources displayed within the GUI of the MMVK, along the fabric of the WWW where the MMVK has been installed. Web-based subsystems are provided for programming these display modes.

Abstract: A lamp having a candle-like appearance and using one or more light-emitting diodes (LEDs) as its light source is presented. The candle-like appearance arises because light is emitted from only a small volume at or near the center of the bulb. The heat sink and control electronics are located outside the bulb of the lamp. Inside the bulb is a set of secondary optics that guide the light from one or more LEDs to an emission point at a prescribed location in the interior of the bulb. The secondary optics include a light pipe that guides light away from the LED chip, and a volume scattering element that receives the light from the light pipe and scatters it into various directions. The volume scattering element is made from a transparent base material, and includes transparent particles of a predetermined size and refractive index.

Abstract: An Internet-based brand marketing communication network for managing and delivering brand marketing communications to consumers using server-side driven multi-mode virtual kiosks (MMVKs) that are created, deployed, and managed using a novel suite of Web-based marketing communication services. For each consumer product registered on the network, a MMVK is created, deployed and installed, so as to establish a virtual brand marketing communication channel between brand management team members and consumers present in e-commerce (EC) enabled market space at the point of MMVK installation in EC-enabled market space, including EC-enabled WWW-sites, EC-enabled stores, EC-enabled online product catalogs, and wherever else consumers are considering the purchase of products on the World Wide Web (WWW).

Abstract: An Internet-based brand marketing communication network for managing and delivering brand marketing communications to consumers using server-side driven multi-mode virtual kiosks (MMVKs) that are created, deployed, and managed using a novel suite of Web-based marketing communication services. For each consumer product registered on the network, a MMVK is created, deployed and installed, so as to establish a virtual brand marketing communication channel between brand management team members and consumers present in e-commerce (EC) enabled market space at the point of MMVK installation in EC-enabled market space, including EC-enabled WWW-sites, EC-enabled stores, EC-enabled online product catalogs, and wherever else consumers are considering the purchase of products on the World Wide Web (WWW).

Abstract: Internet-based Enterprise-Level Brand Management And Marketing Communication Network based on an innovative brand command, control and communication architecture (BC3), which gives brand owners complete command and control over the wide range of brand-building assets, messaging and promotions scattered throughout the Web, and how they are communicated to directly consumers at diverse Web touch points, with the efficiency and automation of supply-chain management solutions. The Network supports the deployment, installation and remote programming of brand-building server-side driven Multi-Mode Virtual Kiosks on the World Wide Web (WWW), and provide brand managers, their agents and online trading partners the power to build stronger online brands, drive sales and eliminate existing friction in the retail chain through a collaborative carrier-class, indutrial-strength e-marketing communication network.

Abstract: A functionally-integrated consumer product and service brand marketing communication system and method which enables manufacturers, retailers, their respective agents, and consumers to carry out four basic product-related marketing communication functions along the demand-side of the retail chain, namely: enabling manufacturers' marketing, brand and/or product managers to create and manage a composite brand image for each consumer product being offered for sale in both physical and electronic marketplaces; enabling manufacturers, retailers, and their advertising and marketing agents to display consumer product advertisements to consumers, at or near the point of purchase or sale within both physical and electronic retail shopping environments, in a way which is guaranteed to project the manufacturer's intended brand image while positively influencing product demand; enabling retailers, manufacturers, and their marketing and promotional agents to promote consumer products with consumers within physical and ele

Abstract: A functionally-integrated consumer product and service brand marketing communication system and method which enables manufacturers, retailers, their respective agents, and consumers to carry out four basic product-related marketing communication functions along the demand-side of the retail chain, namely: enabling manufacturers' marketing, brand and/or product managers to create and manage a composite brand image for each consumer product being offered for sale in both physical and electronic marketplaces; enabling manufacturers, retailers, and their advertising and marketing agents to display consumer product advertisements to consumers, at or near the point of purchase or sale within both physical and electronic retail shopping environments, in a way which is guaranteed to project the manufacturer's intended brand image while positively influencing product demand; enabling retailers, manufacturers, and their marketing and promotional agents to promote consumer products with consumers within physical and ele

Abstract: A functionally-integrated consumer product and service brand marketing communication system and method which enables manufacturers, retailers, their respective agents, and consumers to carry out four basic product-related marketing communication functions along the demand-side of the retail chain, namely: enabling manufacturers' marketing, brand and/or product managers to create and manage a composite brand image for each consumer product being offered for sale in both physical and electronic marketplaces; enabling manufacturers, retailers, and their advertising and marketing agents to display consumer product advertisements to consumers, at or near the point of purchase or sale within both physical and electronic retail shopping environments, in a way which is guaranteed to project the manufacturer's intended brand image while positively influencing product demand; enabling retailers, manufacturers, and their marketing and promotional agents to promote consumer products with consumers within physical and ele