Abstract: Systems and methods include technology that divides first data associated with a first matrix into first multiplication tiles based on a block size that is identified based on an available space of a memory of an accelerator, and second data associated with a second matrix into second multiplication tiles based on the block size. The technology divides the first multiplication tiles into a plurality of first groups that correspond to a plurality of matrix multiplication operations and the second multiplication tiles into a plurality of second groups that correspond to the plurality of matrix multiplication operations. The technology loads a selected first multiplication tile of the first multiplication tiles and a selected second multiplication tile of the second multiplication tiles into the memory to execute one or more of the plurality of matrix multiplication operations with selected groups of the first plurality of groups and the second plurality of groups.