Abstract: The present invention relates to a radiopharmaceutical compound or composition for Positron Emission Tomography (PET) imaging of interleukin-2 (IL2) receptor positive cells, in particular, 68Ga-radiolabelled interleukin-2 such as a desalanyl-1, serine-125 human interleukin-2 (dsIL2) radiolabelled with a short-lived PET radioisotope (or radionuclide) gallium-68 (68Ga) by using tris-(hydroxypyridinone-maleimide) (THP-mal) as a chelator. The invention concerns also a kit comprising dsIL2 linked to THP-mal which can be added with 68Ga in order to obtain the above mentioned radiopharmaceutical, at room temperature, suitable for PET imaging, a process for the preparation of the radiopharmaceutical and its use in medical and diagnostic field.

Abstract: Bicycle tyre (100) comprises a pair of bead cores (8), a carcass structure (2) turned around the pair of bead cores (8) and a tread band (4) radially outer to the carcass structure (2); at each bead core (8) being provided: an elastomeric material filler (12) which extends in a radial direction for a first length (H1) starting from the bead core (8), wherein the first length (H1) is at least 20% of the distance (H4) measured in the radial direction between the bead core (8) and the radially outermost portion of the carcass structure (2).

Abstract: Bicycle tyre (100) which comprises a pair of bead cores (8), a carcass structure (2) turned around the pair of bead cores (8) and a tread band (4) radially outer to the carcass structure (2); at each bead core (8) being provided: an elastomeric material filler (12) which extends in a radial direction for a first length (HI) starting from the bead core (8), a loop (15) interposed between the carcass structure (2) and the elastomeric material filler (12), turned around the bead core (8) so as to define a first flap (15a) axially outer to the elastomeric material filler (12) and a second flap (15b) axially inner to the elastomeric material filler (12), wherein the first flap (15a) extends in a radial direction for a second length (H2) and the second flap (15b) extends in a radial direction for a third length (H3); preferably, the second (H2) and third (H3) lengths are less than or equal to the first length (H1).