Patents by Inventor Filippo Rossignoli

Filippo Rossignoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTISPECIFIC T CELL ENGAGER POLYPEPTIDES IN COMBINATION WITH T CELLS FOR CANCER THERAPY
    Publication number: 20250025510
    Abstract: This technology describes novel cell based combined therapeutic modalities that include a stem cell engineered to secrete a multispecific T cell engager (MiTE) polypeptide construct and an isolated population of T cells that are autologous to the subject.
    Type: Application
    Filed: December 1, 2022
    Publication date: January 23, 2025
    Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Khalid SHAH, Filippo ROSSIGNOLI
  • METHOD TO PRODUCE CONDITIONALLY APOPTOTIC CELLS
    Publication number: 20210214689
    Abstract: The method to produce conditionally apoptotic cells comprises modifying a cell population with a phenotype attributable to human adipose tissue-derived pericytes (AD-PC) expressing anti-tumor TRAIL introducing a sequence coding a conditional suicide gene (CSG).
    Type: Application
    Filed: May 31, 2019
    Publication date: July 15, 2021
    Inventors: Filippo Rossignoli, Carlotta Spano, Giulia Grisendi, Olivia Candini, Massimo Dominici
  • METHOD FOR THE PRODUCTION OF CELLULAR PARTICULATE WITH ANTITUMOR ACTIVITY
    Publication number: 20210054339
    Abstract: Method for the production of cellular particulate with antitumor activity, which comprises isolating the cellular particulate originating from a cell population with a phenotype that can be attributed to human adipose tissue derived pericytes (AD-PC) that express antitumor TRAIL.
    Type: Application
    Filed: April 24, 2019
    Publication date: February 25, 2021
    Inventors: Filippo Rossignoli, Carlotta Spano, Giulia Grisendi, Olivia Candini, Massimo Dominici