Patents by Inventor Filippus Johannes Zeelen

Filippus Johannes Zeelen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4113863
    Abstract: Prostenoic acid derivatives of the general formula ##STR1## wherein R.sup.1 is H or alkyl of 1-4 carbon atoms;R.sup.2 is alkyl of 5 - 9 carbon atoms, phenoxymethyl or phenoxymethyl substituted by up to 3 of F, Cl, Br, CH.sub.3, CF.sub.3, or OCH.sub.3 ;R.sup.3 is H or alkyl of 1 - 5 carbon atoms, and physiologically acceptable salts thereof, as well as intermediates therefore are blood-pressure lowering, vasodilatory, diuretic, and nasal mucosa decongesting agents and are produced from intermediates of the formula ##STR2## wherein R.sup.4 is H or acyl of up to 5 carbon atoms and A is CH.sub.2 D or CH.dbd.C(OR.sup.5); D is carbonyl or dialkoxypolymethylene of up to 7 carbon atoms.
    Type: Grant
    Filed: November 5, 1976
    Date of Patent: September 12, 1978
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Manfred Baumgarth, Hans-Eckart Radunz, Dieter Orth, Reinhard Lissner, Hans-Joachim Enenkel, Filippus Johannes Zeelen
  • Patent number: 4086362
    Abstract: Prostenoic acid derivatives of the general formula ##STR1## wherein R.sup.1 is H or alkyl or 1-4 carbon atoms;R.sup.2 is alkyl of 5 - 9 carbon atoms, phenoxymethyl or phenoxymethyl substituted by up to 3 of F, Cl, Br, CH.sub.3, CF.sub.3, or OCH.sub.3 ;R.sup.3 is H or alkyl or 1 - 5 carbon atoms, and physiologically acceptable salts thereof, as well as intermediates therefore are blood-pressure lowering, vasodilatory, diuretic and nasal mucosa decongesting agents.
    Type: Grant
    Filed: November 24, 1975
    Date of Patent: April 25, 1978
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Manfred Baumgarth, Hans-Eckart Radunz, Dieter Orth, Reinhard Lissner, Hans-Joachim Enenkel, Filippus Johannes Zeelen