Patents by Inventor Finn P. Clausen

Finn P. Clausen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5405857
    Abstract: The present invention relates to hitherto unknown 3-substituted 1,2,3,4-oxatriazole-5-imine compounds which have proved to have biological effects making them suitable for treatment of cardiovascular diseases (blood clots), angina pectoris and asthma, a process for the preparation thereof and a pharmaceutical preparation comprising said compounds.
    Type: Grant
    Filed: July 19, 1993
    Date of Patent: April 11, 1995
    Assignee: A/S GEA Farmaceutisk Fabrik
    Inventors: Gunnar L. Karup, Herbert F. Preikschat, Tim N. Corell, Bodil G. Lissau, Finn P. Clausen, Soren B. Petersen, Borge I. F. Alhede
  • Patent number: 5223619
    Abstract: A process for the preparation of 9-substituted quanine derivatives of general formula (I), in which R is C.sub.1 -C.sub.4 -alkyl optionally substituted with one or more hydroxy groups, or R is (.alpha.), benzyl, ribosyl, 2'-deoxyribosyl or (CH.sub.2).sub.n -OR.sup.1 where n is 1 or 2, and R.sup.1 is CH.sub.2 CH.sub.2 OH or (.beta.) or salts thereof, in which a 1-substituted5-(thiocarbamoyl)amino-1H-imidazole-4-carboxamide of general formula (III), where R has the same meaning as in formula (I), is cyclized: a) by treatment with a heavy metal salt of the group of Cu-, Ag-, Pb- and Hg-salts in an aqueous alkaline medium containing at least for equivalents of OH-ions at a temperature form about 0.degree. C. to the reflux temperature, or b) by treatment with a peroxy compound in an aqueous alkaline medium at a temperature of about 0.degree.-30.degree. C., whereafter (I) is isolated by treatment with a acid and, if desired, is converted into a salt.
    Type: Grant
    Filed: September 20, 1991
    Date of Patent: June 29, 1993
    Assignee: A/S Gea Farmaceutisk Fabrik
    Inventors: Borge Alhede, Finn P. Clausen, Jorgen Juhl-Christensen, Klaus K. McCluskey, Herbert Preikschat