Patents by Inventor Finton Sirockin

Finton Sirockin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9452990
    Abstract: The present invention provides a compound of formula I a method for manufacturing the compounds of the invention, and its therapeutic uses as inhibitor of the complement alternative pathway and particularly as inhibitor of Factor B for the treatment of e.g. age-related macular degeneration and diabetic retinopathy. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: September 27, 2016
    Assignee: NOVARTIS AG
    Inventors: Michael Dechantsreiter, Jonathan E. Grob, Aengus Macsweeney, Wolfgang Miltz, Stefan Andreas Randl, Richard Sedrani, Holger Sellner, Finton Sirockin, Eric Valeur
  • Publication number: 20150126492
    Abstract: The present invention provides a compound of formula I a method for manufacturing the compounds of the invention, and its therapeutic uses as inhibitor of the complement alternative pathway and particularly as inhibitor of Factor B for the treatment of e.g. age-related macular degeneration and diabetic retinopathy. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: June 19, 2013
    Publication date: May 7, 2015
    Applicant: NOVARTIS AG
    Inventors: Michael Dechantsreiter, Jonathan E. Grob, Aengus Macsweeney, Wolfgang Miltz, Stefan Andreas Randl, Richard Sedrani, Holger Sellner, Finton Sirockin, Eric Valeur
  • Publication number: 20130012485
    Abstract: Compounds of the formula (I) are provided: wherein V, W, X, Y, Z, R3, R4, R5, R6, R7 and m are as defined in the specification; and pharmaceutically acceptable salts and prodrugs thereof. The compounds may be useful in the treatment or prevention of various diseases and conditions in which dipeptidylpeptidase-IV (DPP-IV) is implicated.
    Type: Application
    Filed: December 20, 2007
    Publication date: January 10, 2013
    Inventors: Daniel Kaspar Bäschlin, Richard Sedrani, Stefanie Flohr, Kenji Namoto, Nils Ostermann, Finton Sirockin, François Gessier, Garry Fenton, Mandy Christine Beswick, David Edward Clark, Bohdan Waszkowycz
  • Publication number: 20120077787
    Abstract: New compounds of the Formula (I): for the treatment of non-insulin-dependent diabetes mellitus.
    Type: Application
    Filed: December 6, 2011
    Publication date: March 29, 2012
    Applicant: NOVARTIS AG
    Inventors: Daniel Kaspar Baeschlin, Nils OSTERMANN, Francois GESSIER, Finton SIROCKIN, Kenji NAMOTO
  • Patent number: 8097617
    Abstract: New compounds of the Formula (I): for the treatment of non-insulin-dependent diabetes mellitus.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: January 17, 2012
    Assignee: Novartis AG
    Inventors: Daniel Kaspar Baeschlin, Nils Ostermann, Francois Gessier, Finton Sirockin, Kenji Namoto
  • Patent number: 7888351
    Abstract: The present invention relates to compounds of the formula; and their use in therapy.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: February 15, 2011
    Assignee: Novartis AG
    Inventors: Daniel Kaspar Baeschlin, Garry Fenton, Kenji Namoto, Nils Ostermann, Richard Sedrani, Finton Sirockin
  • Publication number: 20110034462
    Abstract: The present invention relates to compounds of the formula; and their use in therapy.
    Type: Application
    Filed: October 15, 2010
    Publication date: February 10, 2011
    Inventors: Daniel Kaspar Baeschlin, Garry Fenton, Kenji Namoto, Nils Ostermann, Richard Sedrani, Finton Sirockin
  • Publication number: 20090281069
    Abstract: The present invention relates to compounds of the formula; and their use in therapy.
    Type: Application
    Filed: April 10, 2007
    Publication date: November 12, 2009
    Inventors: Daniel Kaspar Baeschlin, Garry Fenton, Kenji Namoto, Nils Ostermann, Richard Sedrani, Finton Sirockin
  • Publication number: 20090253689
    Abstract: New compounds of the Formula (I): for the treatment of non-insulin-dependent diabetes mellitus.
    Type: Application
    Filed: March 29, 2007
    Publication date: October 8, 2009
    Inventors: Daniel Kaspar Baeschlin, Nils Ostermann, Francois Gessier, Finton Sirockin, Kenji Namoto
  • Publication number: 20090247577
    Abstract: Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (disorder) that depends on the activity of beta-secretase and/or the generation of beta-amyloid and the subsequent aggregation into oligomers and fibrils; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on the activity of beta-secretase and/or the generation of beta-amyloid and the subsequent aggregation into oligomers and fibrils; pharmaceutical formulations comprising a said substituted pyrrolidine compound, and/or a method of treatment comprising administering a said substituted pyrrolidine compound. The substituted pyrrolidine compounds are especially of the formula I, wherein the substituents are as defined in the specification.
    Type: Application
    Filed: June 4, 2007
    Publication date: October 1, 2009
    Inventors: Olivier Rogel, Jean-Michel Rondeau, Heinrich Rueeger, Oliver Simic, Finton Sirockin, Marina Tintelnot-Blomley
  • Publication number: 20090192138
    Abstract: The invention provides novel deazaxanthine and deazahypoxanthine compounds. The compounds may be useful in the therapy of diseases and conditions in which dipeptidylpeptidase-IV (DPP-IV) is implicated.
    Type: Application
    Filed: December 20, 2006
    Publication date: July 30, 2009
    Inventors: Daniel Kaspar Baeschlin, David Edward Clark, Stephen John Dunsdon, Garry Fenton, Amanda Fillmore, Neil Victor Harris, Christopher Higgs, Christopher Antony Hurley, Sussie Lerche Krintel, Robert Edward Mackenzie, Nils Ostermann, Finton Sirockin, Jonathan Mark Sutton