Patents by Inventor Fiona Duffner

Fiona Duffner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Signal sequence trapping
    Publication number: 20080058214
    Abstract: The present invention allows the screening of previously established genebanks or libraries by proxy for genes encoding secreted, partially secreted, or cell surface-displayed polypeptides of industrial interest, such as enzymes, receptors, cytokines, peptide hormones etc. that would not likely have been isolated using conventional screening assays. A method for isolating genes encoding secreted, partially secreted, or cell surface displayed polypeptides from existing gene libraries is described in which the endogenous secretion signal sequences are detected using an in vitro polynucleotide insertion reaction where the inserted polynucleotide comprises a promoter-less and secretion signal-less secretion reporter.
    Type: Application
    Filed: January 27, 2006
    Publication date: March 6, 2008
    Applicant: Novozymes A/S
    Inventors: Fiona Duffner, Reinhard Wilting, Kirk Schnorr
  • Signal sequence trapping
    Patent number: 7029842
    Abstract: The present invention allows the screening of previously established genebanks or libraries by proxy for genes encoding secreted, partially secreted, or cell surface-displayed polypeptides of industrial interest, such as enzymes, receptors, cytokines, peptide hormones etc. that would not likely have been isolated using conventional screening assays. A method for isolating genes encoding secreted, partially secreted, or cell surface displayed polypeptides from existing gene libraries is described in which the endogenous secretion signal sequences are detected using an in vitro polynucleotide insertion reaction where the inserted polynucleotide comprises a promoter-less and secretion signal-less secretion reporter.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: April 18, 2006
    Assignee: Novozymes A/S
    Inventors: Fiona Duffner, Reinhard Wilting, Kirk Schnorr
  • Method for generating a gene library
    Publication number: 20040121392
    Abstract: The present invention relates to a method of generating a gene library from an environmental pool of organisms, which gene library is enriched in DNA encoding a polypeptide with an activity of interest. Also, the invention provides a method of selecting a DNA sequence of interest from an environmental pool of organisms. Further, the invention relates to a gene library prepared from an enriched environmental pool of organisms enriched in DNA encoding a polypeptide with an activity of interest.
    Type: Application
    Filed: December 8, 2003
    Publication date: June 24, 2004
    Applicant: Novozymes A/S
    Inventors: Thomas Sandal, Carsten Sjoholm, Thomas Shafer, Lene Lange, Fiona Duffner
  • Method for generating a gene library
    Patent number: 6723504
    Abstract: The present invention relates to a method of generating a gene library from an environmental pool of organisms, which gene library is enriched in DNA encoding a polypeptide with an activity of interest. Also, the invention provides a method of selecting a DNA sequence of interest from an environmental pool of organisms. Further, the invention relates to a gene library prepared from an enriched environmental pool of organisms enriched in DNA encoding a polypeptide with an activity of interest.
    Type: Grant
    Filed: October 25, 1999
    Date of Patent: April 20, 2004
    Assignee: Novozymes A/S
    Inventors: Thomas Sandal, Carsten Sjøholm, Thomas Schäfer, Lene Lange, Fiona Duffner
  • Signal sequence trapping
    Publication number: 20020076706
    Abstract: The present invention allows the screening of previously established genebanks or libraries by proxy for genes encoding secreted, partially secreted, or cell surface-displayed polypeptides of industrial interest, such as enzymes, receptors, cytokines, peptide hormones etc. that would not likely have been isolated using conventional screening assays. A method for isolating genes encoding secreted, partially secreted, or cell surface displayed polypeptides from existing gene libraries is described in which the endogenous secretion signal sequences are detected using an in vitro polynucleotide insertion reaction where the inserted polynucleotide comprises a promoter-less and secretion signal-less secretion reporter.
    Type: Application
    Filed: March 30, 2001
    Publication date: June 20, 2002
    Applicant: Novozymes A/S
    Inventors: Fiona Duffner, Reinhard Wilting, Kirk Schnorr
  • Desulfurococcus amylopullulanase
    Patent number: 6043074
    Abstract: The present invention relates to Desulfurococcus amylopullulanase preparations and their use in producing sweeteners and ethanol from starch.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: March 28, 2000
    Assignee: Novo Nordisk A/S
    Inventor: Fiona Duffner