Patents by Inventor Fiona MCROBB

Fiona MCROBB has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CBL-B MODULATORS AND USES THEREOF
    Publication number: 20250263399
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of Cbl-b, and the treatment of Cbl-b-mediated disorders.
    Type: Application
    Filed: May 6, 2025
    Publication date: August 21, 2025
    Inventors: Silvana Marcel Leit de Moradei, Angela V. West, Thomas Baker, Jokin Carrillo Arregui, Diana Castagna, Jeremy Robert Greenwood, Salma Rafi, Fiona McRobb, Yan Zhang
  • CBL-B modulators and uses thereof
    Patent number: 12325697
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of Cbl-b, and the treatment of Cbl-b-mediated disorders.
    Type: Grant
    Filed: April 8, 2022
    Date of Patent: June 10, 2025
    Assignee: Nimbus Clio, Inc.
    Inventors: Silvana Marcel Leit De Moradei, Angela V. West, Thomas Baker, Jokin Carrillo Arregui, Diana Castagna, Jeremy Robert Greenwood, Salma Rafi, Fiona McRobb, Yan Zhang
  • CBL-B MODULATORS AND USES THEREOF
    Publication number: 20250163038
    Abstract: The invention provides compounds, compositions thereof, and methods of using the same for the inhibition of Cbl-b, and the treatment of a variety of Cbl-b-mediated diseases, disorders or conditions, associated with modulating the immune system implicating Cbl-b. Compounds are also useful for the study of Cbl-b enzymes in biological and pathological phenomena; the study of ubiquitination occurring in bodily tissues; and the comparative evaluation of new Cbl-b inhibitors or other regulators of cell cycle, DNA repair, differentiation, and innate and adaptive immunity in vitro or in vivo.
    Type: Application
    Filed: June 21, 2022
    Publication date: May 22, 2025
    Inventors: Silvana Marcel LEIT DE MORADEI, Angela V. WEST, Thomas BAKER, Jokin Carrillo ARREGUI, Diana CASTAGNA, Jeremy Robert GREENWOOD, Salma RAFI, Fiona MCROBB, Yan ZHANG
  • SRC INHIBITORS AND USES THEREOF
    Publication number: 20250154154
    Abstract: The present invention relates to compounds and methods useful for inhibiting non-receptor tyrosine-protein kinase Src (“Src”). The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
    Type: Application
    Filed: November 17, 2021
    Publication date: May 15, 2025
    Inventors: Demetri T. MOUSTAKAS, Lucian V. DIPIETRO, Heike SCHOENHERR, Bakary-Barry TOURÉ, W. Patrick WALTERS, Mark A. MURCKO, Ravi KURUKULASURIYA, Levi Charles Thomas PIERCE, Fabrizio GIORDANETTO, Yibing SHAN, Shiori SAGAWA, Goran KRILOV, Fiona MCROBB, Eric THERRIEN
  • CBL-B MODULATORS AND USES THEREOF
    Publication number: 20230086064
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of Cbl-b, and the treatment of Cbl-b-mediated disorders.
    Type: Application
    Filed: April 8, 2022
    Publication date: March 23, 2023
    Inventors: Silvana Marcel LEIT DE MORADEI, Angela V. WEST, Thomas BAKER, Jokin Carrillo ARREGUI, Diana CASTAGNA, Jeremy Robert GREENWOOD, Salma RAFI, Fiona MCROBB, Yan ZHANG