Abstract: A stent, such as transluminal stent, is disclosed. The stent includes a tubular member with a proximal end, a distal end, and a central portion therebetween. The elongate tubular member comprises a scaffolding forming a plurality of cells and defining a lumen of the elongate tubular member. A proximal portion of the tubular member forms a retention member, wherein the diameter of the retention member is greater than the diameter of the central portion, and wherein a proximal end of the retention member includes an area of increased scaffolding density.

Abstract: A medical stent including a tubular scaffold is disclosed. The tubular scaffold is formed from a single wire extending helically from a first end to a second end along a central longitudinal axis such that the single wire forms a plurality of helical windings around the central longitudinal axis. A polymeric covering is disposed on the tubular scaffold and spans gaps between adjacent helical windings of the tubular scaffold. The stent includes a plurality of longitudinal reinforcing strips extending along the tubular scaffold parallel to the central longitudinal axis. The reinforcing strips are configured to restrict elongation of the stent by less than 5% when the stent shifts between a radially collapsed delivery configuration and a radially expanded deployed configuration.

Abstract: An endoprosthesis includes a body portion extending from a first end to a second end along a central longitudinal axis. The body portion is formed from a single wire extending from the first end to the second end and forming a plurality of circumferential segments extending non-helically around the axis. The plurality of circumferential segments includes a first end circumferential segment forming the first end, a second end circumferential segment forming the second end, and at least one medial circumferential segment disposed between the first and second end circumferential segments. Each circumferential segment includes an undulating arrangement of first struts and second struts defining peaks and valleys, the first and second struts being disposed at first and second angles, respectively, relative to the axis in a side view of the body portion. Peaks and valleys of adjacent circumferential segments may be axially aligned with each other parallel to the axis.

Abstract: An endoprosthesis includes a body portion extending axially from a first end to a second end. The body portion is formed from a single wire extending from the first end to the second end. The single wire forms a plurality of circumferential rings. Each circumferential ring comprises an undulating arrangement of struts defining peaks and valleys. At least one circumferential ring may include a loop formed at each peak or at each valley of the at least one circumferential ring. A loop may be formed at each peak or at each valley of each circumferential ring. A loop may be formed at each peak and at each valley of each circumferential ring.

Abstract: A stent is disclosed. The stent includes a tubular scaffold extending from a first end to a second end in which the tubular scaffold is formed of a single filament shaped to form a plurality of open cells throughout the tubular scaffold. Each of the open cells may be formed as a parallelogram shape defined by two pairs of opposing linear sections of the filament and pseudo hooked sections of the filament at each apex of the plurality of open cells, wherein each of apices of the plurality of open cells includes a pseudo hooked region in which first and second bends of the single filament overlap one another. The open cells may include first and second helical rows of small open cells, and a first helical row of large open cells positioned therebetween.

Abstract: An endoprosthesis, such as a stent, includes a body portion extending axially from a first end to a second end along a central longitudinal axis; wherein the body portion is formed from a single wire extending from the first end to the second end and where the single wire forms a plurality of circumferential segments extending non-helically around the central longitudinal axis; and a reinforcing filament extending substantially longitudinally along the body portion.

Abstract: A stent is disclosed. The stent includes a tubular scaffold extending from a first end to a second end in which the tubular scaffolding is formed of a single filament woven to form a plurality of open cells throughout the tubular scaffold. Each of the open cells may be formed as a parallelogram shape defined by two pairs of opposing linear sections of the filament and hooked sections of the filament at each apex of the plurality of open cells, wherein each of apices of the plurality of open cells includes a hooked region in which the single filament is intertwined with itself and changes weaving direction. The open cells may include first and second helical rows of small open cells, and a first helical row of large open cells positioned therebetween.

Abstract: A stent comprises a tubular scaffold formed of a single filament that is woven to define a plurality of open cells; wherein the plurality of open cells includes a helical row of large open cells, a first helical row of small open cells, and a second helical row of small open cells; and a reinforcing filament extending substantially longitudinally along the tubular scaffold.

Abstract: A delivery system for delivering an implant to a body lumen of a patient. The delivery system may include a hub, an elongate shaft coupled with the hub, and a thread for securing the implant to the elongate shaft. The elongate shaft may include a proximal portion at least partially defining a first lumen and a second lumen, a distal portion at least partially defining the first lumen, and a side port in the proximal portion and distal of the hub. The side port may be in communication with the first lumen. The thread may include a distal portion configured to wrap around the distal portion of the elongate shaft and/or the implant and a proximal portion configured to extend through the second lumen. The delivery system may be configured to deliver the implant to a target location in a lumen of a biliary tract of the patient.

Abstract: Stents and/or implants including a reinforcement member. An illustrative transluminal implant may include an elongated tubular body extending from first end region to a second end region. The elongated tubular body may comprise a scaffolding forming a plurality of cells, a first flange adjacent to the first end region, a second flange adjacent to the second end region, and a saddle region extending between the first flange and the second flange. The saddle region may have an outer diameter less than an outer diameter of the first flange and the second flange. A reinforcement member may be disposed within a lumen of the elongated tubular body and within the first flange.

Abstract: A stent including a tubular body having first and second opposing open ends and a lumen extending therebetween. The stent including a first anchor member disposed adjacent the first open end and a second anchor member disposed adjacent the second open end, the first and second anchor members spaced apart by a saddle region of the tubular body, the first and second anchor members each extending radially outward from the tubular body, the first and second anchor members each have an outer diameter larger than an outer diameter of the saddle region disposed between the first and second anchor members. Each of the first and second anchor members include an outer wall, and an inner wall spaced apart from the outer wall, and the tubular body is defined by only a single wall.

Abstract: An implantable medical device, such as a stent, having a dynamic feature allowing movement of one or both of the ends of the implantable medical device relative to the intermediate section therebetween. The implantable medical device may be sized, shaped, configured, and/or dimensioned to hold anatomical structures in apposition. The dynamic section allows relative movement of the apposed anatomical structures without causing migration of the ends of the implantable medical device which are anchored with respect to the anatomical structures.

Abstract: An implantable medical device system having at least two implantable medical devices coupled together with a connector while implanted at a common anatomical region. The connector allows the implantable medical devices to anchor one another in place at respective deployment sites. Moreover, the connector may function as a safety device by causing one implantable medical device to migrate upon migration of another implantable medical device. For instance, if migration of an implantable medical device causes a structural change in the common anatomical region, such change may be generally reversible upon migration of the other implantable medical device as a result of the implantable medical devices being coupled via the connector.

Abstract: An implantable medical device with at least a portion of a wall thereof being coated to prevent fluid flow therethrough, and having one or more uncoated anti-migration features promoting tissue ingrowth therearound. The anti-migration features may be partially-closed or fully closed shapes forming a retention portion transverse to the direction along which migration forces typically impact the implantable medical device at the anatomical site at which the implantable medical device is to be deployed.

Abstract: An example medical device may include a stent including a radially expanding tubular framework having a radially outward surface, a radially inward surface, a first end region, a second end region, a medial region positioned between the first end region and the second end region, and a lumen extending from the first end region to the second end region. A first flange structure may be positioned near the first end region, and a second flange structure may be positioned near the second end region. One of the first end region or the second end region may include a third flange structure.

Abstract: An example medical device includes a stent having a radially expanding tubular framework. The radially expanding tubular framework includes a first end region, a second end region, a medial region positioned between the first end region and the second end region, and a lumen extending from the first end region to the second end region. The stent further includes a tubular structure positioned over the medial region, the tubular structure is formed from a bioabsorbable material, and is configured to hold the medial region in a first, compressed configuration. Upon bioabsorption of the tubular structure, the medial region of the tubular framework radially expands to a second, expanded configuration. One of the first end region or the second end region includes a first flange structure.

Abstract: An implantable medical device includes an elongate body extending from a distal region to a proximal region, at least one of the distal region and the proximal region including a flared region defining an inner flared surface. One or more visual indicators are positioned relative to the inner flared surface such that the one or more visual indicators are visible endoscopically from a position within or proximate the implantable stent.

Abstract: A replacement heart valve system may include a delivery sheath and a replacement heart valve. The replacement heart valve may include a mesh anchor member disposed within the delivery sheath in an elongated delivery configuration, the mesh anchor member being expandable to a deployed configuration when unconstrained by the delivery sheath. The mesh anchor member may include an upstream chamber, a downstream chamber, and a tubular middle portion extending between the upstream chamber and the downstream chamber. The replacement heart valve may include a diaphragm disposed within the downstream chamber of the mesh anchor member, wherein the diaphragm is configured to selectively prevent fluid flow through the replacement heart valve.

Abstract: A replacement heart valve system may include a delivery sheath and a replacement heart valve. The replacement heart valve may include a mesh anchor member disposed within the delivery sheath in an elongated delivery configuration, the mesh anchor member being expandable to a deployed configuration when unconstrained by the delivery sheath. The mesh anchor member may include an upstream chamber, a downstream chamber, and a tubular middle portion extending between the upstream chamber and the downstream chamber. The replacement heart valve may include a diaphragm disposed within the downstream chamber of the mesh anchor member, wherein the diaphragm is configured to selectively prevent fluid flow through the replacement heart valve.