Patents by Inventor Fiorella Carla Grande

Fiorella Carla Grande has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF OSTEOARTHRITIS
    Publication number: 20220347182
    Abstract: Provided herein are methods and compositions for reducing inflammation and/or treating osteoarthritis in a patient in need thereof. The methods include administering to the patient an inhibitor of an inflammation amplifying (Inf-A) population of chondrocytes and an activator of an inflammation dampening (Inf-D) population of chondrocytes. The methods include exposing the osteoarthritic chondrocytes to a composition including an effective amount of an ALK5 inhibitor, a JNK kinase inhibitor, a TNFR II receptor inhibitor, and/or IL1R1 receptor inhibitor and an effective amount of a CD24 activator.
    Type: Application
    Filed: October 2, 2020
    Publication date: November 3, 2022
    Inventors: Nidhi Bhutani, Fiorella Carla Grande