Patents by Inventor Firas Mourtada
Firas Mourtada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8579967Abstract: An apparatus including a tether, and an aptation device coupled to the tether at a position corresponding to a location to contact cusps of an atrioventricular valve during systole, wherein the tether and aptation device are suitable for percutaneous delivery to a patient. An apparatus including a support annulus comprising a length corresponding to a circumference of one of an interior portion of an atrium and an atrioventricular valve annulus; and an aptation device coupled to the support annulus corresponding to a location to contact cusps of an atrioventricular valve during at least one of systole when the support annulus is seated in one of an atrium and an atrioventricular valve annulus, wherein the support annulus and aptation device are suitable for percutaneous delivery to a patient. Also, a method of introducing an aptation device to contact cusps or leaflets of an atrioventricular valve.Type: GrantFiled: April 11, 2011Date of Patent: November 12, 2013Assignee: Advanced Cardiovascular Systems, Inc.Inventors: William E. Webler, James D. Breeding, Brad D. Bisson, Firas Mourtada, Gregory M. Hyde, Stephanie A. Szobota, Gabriel Asongwe, Jeffrey T. Ellis
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Publication number: 20110184512Abstract: An apparatus including a tether, and an aptation device coupled to the tether at a position corresponding to a location to contact cusps of an atrioventricular valve during systole, wherein the tether and aptation device are suitable for percutaneous delivery to a patient. An apparatus including a support annulus comprising a length corresponding to a circumference of one of an interior portion of an atrium and an atrioventricular valve annulus; and an aptation device coupled to the support annulus corresponding to a location to contact cusps of an atrioventricular valve during at least one of systole when the support annulus is seated in one of an atrium and an atrioventricular valve annulus, wherein the support annulus and aptation device are suitable for percutaneous delivery to a patient. Also, a method of introducing an aptation device to contact cusps or leaflets of an atrioventricular valve.Type: ApplicationFiled: April 11, 2011Publication date: July 28, 2011Inventors: William E. Webler, James D. Breeding, Brad D. Bisson, Firas Mourtada, Gregory M. Hyde, Stephanie A. Szobota, Gabriel Asongwe, Jeffrey T. Ellis
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Patent number: 7942928Abstract: An apparatus including a tether, and an aptation device coupled to the tether at a position corresponding to a location to contact cusps of an atrioventricular valve during systole, wherein the tether and aptation device are suitable for percutaneous delivery to a patient. An apparatus including a support annulus comprising a length corresponding to a circumference of one of an interior portion of an atrium and an atrioventricular valve annulus; and an aptation device coupled to the support annulus corresponding to a location to contact cusps of an atrioventricular valve during at least one of systole when the support annulus is seated in one of an atrium and an atrioventricular valve annulus, wherein the support annulus and aptation device are suitable for percutaneous delivery to a patient. Also, a method of introducing an aptation device to contact cusps or leaflets of an atrioventricular valve.Type: GrantFiled: February 5, 2008Date of Patent: May 17, 2011Assignee: Advanced Cardiovascular Systems, Inc.Inventors: William E. Webler, James D. Breeding, Brad D. Bisson, Firas Mourtada, Gregory M. Hyde, Stephanie A. Szobota, Gabriel Asongwe, Jeffrey T. Ellis
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Patent number: 7927370Abstract: An apparatus including a tether, and an aptation device coupled to the tether at a position corresponding to a location to contact cusps of an atrioventricular valve during systole, wherein the tether and aptation device are suitable for percutaneous delivery to a patient. An apparatus including a support annulus comprising a length corresponding to a circumference of one of an interior portion of an atrium and an atrioventricular valve annulus; and an aptation device coupled to the support annulus corresponding to a location to contact cusps of an atrioventricular valve during at least one of systole when the support annulus is seated in one of an atrium and an atrioventricular valve annulus, wherein the support annulus and aptation device are suitable for percutaneous delivery to a patient. Also, a method of introducing an aptation device to contact cusps or leaflets of an atrioventricular valve.Type: GrantFiled: February 5, 2008Date of Patent: April 19, 2011Assignee: Advanced Cardiovascular Systems, Inc.Inventors: William E. Webler, James D. Breeding, Brad D. Bisson, Firas Mourtada, Gregory M. Hyde, Stephanie A. Szobota, Gabriel Asongwe, Jeffrey T. Ellis
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Patent number: 7651458Abstract: The invention is a novel adaptive CT-friendly brachytherapy applicator with remotely-controlled radial and longitudinal motion radioactive source lumen shields that can be manipulated by the radiation oncologist to optimize the dose distribution to the target and normal tissue structures for brachytherapy procedures.Type: GrantFiled: July 28, 2006Date of Patent: January 26, 2010Assignee: Board of Regents The University of Texas SystemInventors: Firas Mourtada, John Horton, Patricia Eifel, Anuja Jhingran, Ira Spool
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Patent number: 7586102Abstract: The present invention provides automated systems for the purification of radioisotopes, the formulation of radiopharmaceuticals or both. In preferred embodiments the radioisotopes are produced by a generator. In further preferred embodiments the automated systems comprise replaceable cassettes for easy replacement of the system's networks of tubing. Also provided are replaceable cassettes and kits for use with the automated systems of the invention. The invention further provides methods of using an automated system to purify radioisotopes, formulate radiopharmaceuticals or to do both in series.Type: GrantFiled: March 23, 2007Date of Patent: September 8, 2009Assignee: Board of Regents the University of Texas SystemInventors: Firas Mourtada, Ali Azhdarinia, David Yang, Changsok Oh
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Patent number: 7556596Abstract: The invention is a novel adaptive CT-compatible brachytherapy applicator with remotely-controlled radial and longitudinal motion radioactive source lumen shields that can be manipulated by the radiation oncologist to optimize the dose distribution to the target and normal tissue structures for brachytherapy procedures.Type: GrantFiled: July 20, 2005Date of Patent: July 7, 2009Assignee: Board of Regents The University of Texas SystemInventors: Firas Mourtada, John Horton, Patricia Eifel, Anuja Jhingran, Ira Spool
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Publication number: 20080199370Abstract: The present invention provides an efficient infrared (IR) reaction vessel system that includes an infrared reaction vessel having an optical window into a reaction reservoir that absorbs minimal infrared energy, a male cap attached to the reaction vessel that allows precise positioning with respect to an infrared heat source, and at least one access tube passing through the cap. The infrared reaction vessel of the present invention further provides vacuum lines that also repulse ions and minimize evaporation loss and novel temperature control feedbacks such as the use of a proximally positioned resistive thermal device (RTD).Type: ApplicationFiled: December 20, 2007Publication date: August 21, 2008Inventors: Firas Mourtada, Ali Azhdarinia, David Yang, Christian Landry
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Patent number: 7404824Abstract: An apparatus including a tether, and an aptation device coupled to the tether at a position corresponding to a location to contact cusps of an atrioventricular valve during systole, wherein the tether and aptation device are suitable for percutaneous delivery to a patient. An apparatus including a support annulus comprising a length corresponding to a circumference of one of an interior portion of an atrium and an atrioventricular valve annulus; and an aptation device coupled to the support annulus corresponding to a location to contact cusps of an atrioventricular valve during at least one of systole when the support annulus is seated in one of an atrium and an atrioventricular valve annulus, wherein the support annulus and aptation device are suitable for percutaneous delivery to a patient. Also, a method of introducing an aptation device to contact cusps or leaflets of an atrioventricular valve.Type: GrantFiled: November 12, 2003Date of Patent: July 29, 2008Assignee: Advanced Cardiovascular Systems, Inc.Inventors: William E. Webler, James D. Breeding, Brad D. Bisson, Firas Mourtada, Gregory M. Hyde, Stephanie A. Szobota, Gabriel Asongwe, Jeffrey T. Ellis
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Publication number: 20080125861Abstract: An apparatus including a tether, and an aptation device coupled to the tether at a position corresponding to a location to contact cusps of an atrioventricular valve during systole, wherein the tether and aptation device are suitable for percutaneous delivery to a patient. An apparatus including a support annulus comprising a length corresponding to a circumference of one of an interior portion of an atrium and an atrioventricular valve annulus; and an aptation device coupled to the support annulus corresponding to a location to contact cusps of an atrioventricular valve during at least one of systole when the support annulus is seated in one of an atrium and an atrioventricular valve annulus, wherein the support annulus and aptation device are suitable for percutaneous delivery to a patient. Also, a method of introducing an aptation device to contact cusps or leaflets of an atrioventricular valve.Type: ApplicationFiled: February 5, 2008Publication date: May 29, 2008Inventors: William E. Webler, James D. Breeding, Brad D. Bisson, Firas Mourtada, Gregory M. Hyde, Stephanie A. Szobota, Gabriel Asongwe, Jeffrey T. Ellis
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Publication number: 20080125860Abstract: An apparatus including a tether, and an aptation device coupled to the tether at a position corresponding to a location to contact cusps of an atrioventricular valve during systole, wherein the tether and aptation device are suitable for percutaneous delivery to a patient. An apparatus including a support annulus comprising a length corresponding to a circumference of one of an interior portion of an atrium and an atrioventricular valve annulus; and an aptation device coupled to the support annulus corresponding to a location to contact cusps of an atrioventricular valve during at least one of systole when the support annulus is seated in one of an atrium and an atrioventricular valve annulus, wherein the support annulus and aptation device are suitable for percutaneous delivery to a patient. Also, a method of introducing an aptation device to contact cusps or leaflets of an atrioventricular valve.Type: ApplicationFiled: February 5, 2008Publication date: May 29, 2008Inventors: William E. Webler, James D. Breeding, Brad D. Bisson, Firas Mourtada, Gregory M. Hyde, Stephanie A. Szobota, Gabriel Asongwe, Jeffrey T. Ellis
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Publication number: 20080035542Abstract: The present invention provides automated systems for the purification of radioisotopes, the formulation of radiopharmaceuticals or both. In preferred embodiments the radioisotopes are produced by a generator. In further preferred embodiments the automated systems comprise replaceable cassettes for easy replacement of the system's networks of tubing. Also provided are replaceable cassettes and kits for use with the automated systems of the invention. The invention further provides methods of using an automated system to purify radioisotopes, formulate radiopharmaceuticals or to do both in series.Type: ApplicationFiled: March 23, 2007Publication date: February 14, 2008Applicant: Board of Regents, The University of Texas SystemInventors: Firas Mourtada, Ali Azhdarinia, David Yang, Changsok Oh
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Publication number: 20070027352Abstract: The invention is a novel adaptive CT-friendly brachytherapy applicator with remotely-controlled radial and longitudinal motion radioactive source lumen shields that can be manipulated by the radiation oncologist to optimize the dose distribution to the target and normal tissue structures for brachytherapy procedures.Type: ApplicationFiled: July 28, 2006Publication date: February 1, 2007Applicant: Board of Regents, The University of Texas SystemInventors: Firas Mourtada, John Horton, Patricia Eifel, Anuja Jhingran, Ira Spool
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Publication number: 20060235260Abstract: The invention is a novel adaptive CT-compatible brachytherapy applicator with remotely-controlled radial and longitudinal motion radioactive source lumen shields that can be manipulated by the radiation oncologist to optimize the dose distribution to the target and normal tissue structures for brachytherapy procedures.Type: ApplicationFiled: July 20, 2005Publication date: October 19, 2006Applicant: Board of Regents, The University of Texas SystemInventors: Firas Mourtada, John Horton, Patricia Eifel, Anuja Jhingran, Ira Spool
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Publication number: 20050276751Abstract: Systems and methods are described for efficiently producing a radiopharmaceutical agent. The system includes a generator that provides an admixture comprising hydrochloric acid and gallium-68 (Ga-68). A heater initiates a removal process by evaporating the hydrochloric acid from the admixture resulting in a substantially purified Ga-68. A plurality of valves provides a buffer and a prodrug that gets mixed with the Ga-68 to produce Ga-68 radiopharmaceutical agent. Additionally, the valves may provide water or a transchelator to the Ga-68 radiopharmaceutical agent to optimize the yield. A method includes providing an admixture comprising hydrochloric acid and Ga-68. The method also includes removing the hydrochloric acid by heating the admixture and subsequently evaporating the hydrochloric acid, resulting in a substantially purified Ga-68. The method further includes adding a buffer and a prodrug to the substantially purified Ga-68 to produce the Ga-68 radiopharmaceutical agent.Type: ApplicationFiled: January 19, 2005Publication date: December 15, 2005Inventors: K.S. Chao, David Yang, Firas Mourtada, Ali Azhdarinia
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Patent number: 6605031Abstract: A stepped centering catheter for delivery of intravascular radiation therapy including a central segment of a first effective diameter and smaller, offset segments of second effective diameters to each side of the central segment. The first effective diameter of the central segment substantially centers a portion of a radiation source within the lumen of a vessel along a therapeutic treatment length. The second effective diameters of the offset segments constrain portions of the radioactive source that extend beyond the therapeutic treatment length within a region having a minimum offset distance from the vessel wall. The first effective diameter of the central segment is gradually tapered to the second effective diameter of the offset segments across first steps. The second effective diameters of the offset segments are gradually tapered to the diameter of the catheter shaft across second steps.Type: GrantFiled: February 16, 2000Date of Patent: August 12, 2003Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Firas Mourtada, Eric D. Peterson