Abstract: A method of improving electrical conduction across an impaired region of a tissue (e.g., myocardial tissue), includes applying an electrically conductive wiring (e.g., carbon nanotube fibers) across the impaired region. The electrically conductive wiring can become associated with non-impaired regions of the tissue on opposite sides of the impaired region by suturing. The method can also be utilized to treat or prevent cardiac arrhythmia in a subject (e.g., ventricular arrhythmia). The electrically conductive wiring includes carbon nanotubes, such as carbon nanotube fibers. Such electrically conductive wiring can be used to transmit electrical signals to a tissue or sense electrical signals from the tissue. Suture threads including carbon nanotubes, such as carbon nanotube fibers, are provided.

Abstract: A biosignal sensing electrode, including: a substrate; a conductive film on the substrate, the conductive film containing particles of a layered material containing one or plural layers, the one or plural layers being oriented parallel to a surface of the substrate and containing a layer body represented by: MmXn, with a modifier or terminal T existing on a surface of the layer body; and a protective material containing a polymer having C?O and at least one of OH and NH as a functional group covering at least an edge of the conductive film, the functional group being bonded to the particles of the layered material, and at least a part of the second face of the conductive film is exposed from the protective material.

Abstract: A health monitor, comprising: an electrode that includes a hydrogel composition comprising a first network that comprises at least two hydroxyl-bearing chains of a first polymer, the at least two hydroxyl-bearing polymer chains being crosslinked by crosslinks that comprise one or more boronic ester bonds; and at least one conductive additive dispersed within the composition, the electrode being configured for patient contact. Also provided are related methods.

Abstract: Methods and systems for automated detection of neuropsychiatric disorders are described herein. In one aspect, a method can include measuring, via a wearable device of a diagnostic system, one or more electrical signals corresponding to muscle movement of a user, wherein the wearable device comprises one or more MXene-comprising sensors; inputting information indicative of the one or more electrical signals into a trained model; determining, by the trained model and based on the inputted information, whether the user is experiencing symptoms of a neuropsychiatric disorder; and sending information indicative of the determining to a component of the diagnostic system.

Abstract: A method of improving electrical conduction across an impaired region of a tissue (e.g., myocardial tissue), includes applying an electrically conductive wiring (e.g., carbon nanotube fibers) across the impaired region. The electrically conductive wiring can become associated with non-impaired regions of the tissue on opposite sides of the impaired region by suturing. The method can also be utilized to treat or prevent cardiac arrhythmia in a subject (e.g., ventricular arrhythmia). The electrically conductive wiring includes carbon nanotubes, such as carbon nanotube fibers. Such electrically conductive wiring can be used to transmit electrical signals to a tissue or sense electrical signals from the tissue. Suture threads including carbon nanotubes, such as carbon nanotube fibers, are provided.

Abstract: A medical device (10) and method for infusing a drug or like substance in vivo within tissue of an organ of a patient are provided. The device (10) includes an outer cannula (12) having a distal and proximal ends (14, 16) and a plurality of microcannulas (20, 22, 24) extending within a length of the outer cannula (12). Each of the microcannulas (20, 22, 24) having a distal end (28) and a proximal end (26) and being movable relative to the outer cannula (12) in a lengthwise direction between retracted and extended positions such that, in the retracted position, the distal ends (28) of the microcannulas (20, 22, 24) are located within the outer cannula (12) and, in the extended position, the distal ends (28) of the microcannulas (20, 22, 24) extend beyond the distal end (14) of the outer cannula (12) in a splayed configuration.

Abstract: An electrode including: a conductive film which contains: a layered material having one or plural layers of particles of a layer body represented by: MmXn (M is at least one metal of Group 3, 4, 5, 6, or 7, X is a carbon atom, a nitrogen atom, or a combination thereof, n is not less than 1 and not more than 4, and m is more than n but not more than 5), and a modifier or terminal T existing on a surface of the layer body, (T is at least one selected from a hydroxyl group, a fluorine atom, a chlorine atom, an oxygen atom, and a hydrogen atom); and a ?-electron conjugated compound attached to the particles and having at least one selected from the group consisting of an aromatic ring, a heteroaromatic ring, a conjugated diene unit, an allyl group, and a vinyl group.

Abstract: An electrode including: a conductive film which contains: a layered material having one or plural layers of particles of a layer body represented by: MmXn (M is at least one metal of Group 3, 4, 5, 6, or 7, X is a carbon atom, a nitrogen atom, or a combination thereof, n is not less than 1 and not more than 4, and m is more than n but not more than 5), and a modifier or terminal T existing on a surface of the layer body, (T is at least one selected from a hydroxyl group, a fluorine atom, a chlorine atom, an oxygen atom, and a hydrogen atom); and a ?-electron conjugated compound attached to the particles and having at least one selected from the group consisting of an aromatic ring, a heteroaromatic ring, a conjugated diene unit, an allyl group, and a vinyl group.

Abstract: A biosignal sensing electrode, including: a substrate; a conductive film on the substrate, the conductive film containing particles of a layered material containing one or plural layers, the one or plural layers being oriented parallel to a surface of the substrate and containing a layer body represented by: MmXn, with a modifier or terminal T existing on a surface of the layer body; and a protective material containing a polymer having C?O and at least one of OH and NH as a functional group covering at least an edge of the conductive film, the functional group being bonded to the particles of the layered material, and at least a part of the second face of the conductive film is exposed from the protective material.

Abstract: An electrode comprising: a ? electron conjugated compound film which includes a ? electron conjugated compound having at least one of an aromatic ring, a heteroaromatic ring, a carbon-carbon double bond, a carbon-carbon triple bond, and a carbon-phosphorus double bond; and a conductive film bonded to the r electron conjugated compound film, the conductive film including particles of a layered material of one or plural layers having a layer body represented by: MmXn, wherein M is at least one metal of Group 3 through 7, X is a carbon atom, a nitrogen atom, or a combination thereof, n is 1 to 4, and m is more than n but not more than 5, and a modifier or terminal T existing on a surface of the layer body, wherein T is at least one of a hydroxyl group, a fluorine atom, a chlorine atom, an oxygen atom, and a hydrogen atom.

Abstract: An electrode, the electrode including an exposed contact surface, the exposed surface comprising a contact material, the contact material comprising a MXene. A device, the device including a plurality of electrodes, each of the plurality of electrodes comprising an exposed contact surface, the exposed surface comprising a contact material, the contact material comprising a MXene. A method, the method including delivering electrical stimulation to a subject with an electrode that comprises an exposed contact surface, the exposed contact surface comprising a contact material that includes a MXene.

Abstract: A health monitor, comprising: an electrode that includes a hydrogel composition comprising a first network that comprises at least two hydroxyl-bearing chains of a first polymer, the at least two hydroxyl-bearing polymer chains being crosslinked by crosslinks that comprise one or more boronic ester bonds; and at least one conductive additive dispersed within the composition, the electrode being configured for patient contact. Also provided are related methods.

Abstract: A method of improving electrical conduction across an impaired region of a tissue (e.g., myocardial tissue), includes applying an electrically conductive wiring carbon nanotube fibers) across the impaired region. The electrically conductive wiring can become associated with non-impaired regions of the tissue on opposite sides of the impaired region by suturing. The method can also be utilized to treat or prevent cardiac arrhythmia in a subject (e.g., ventricular arrhythmia). The electrically conductive wiring includes carbon nanotubes, such as carbon nanotube fibers, Such electrically conductive wiring can be used to transmit electrical signals to a tissue or sense electrical signals from the tissue. Suture threads including carbon nanotubes, such as carbon nanotube fibers, are provided.

Abstract: A medical device (10) and method for infusing a drug or like substance in vivo within tissue of an organ of a patient are provided. The device (10) includes an outer cannula (12) having a distal and proximal ends (14, 16) and a plurality of microcannulas (20, 22, 24) extending within a length of the outer cannula (12). Each of the microcannulas (20, 22, 24) having a distal end (28) and a proximal end (26) and being movable relative to the outer cannula (12) in a lengthwise direction between retracted and extended positions such that, in the retracted position, the distal ends (28) of the microcannulas (20, 22, 24) are located within the outer cannula (12) and, in the extended position, the distal ends (28) of the microcannulas (20, 22, 24) extend beyond the distal end (14) of the outer cannula (12) in a splayed configuration.

Abstract: Provided are electrodes that comprise MXene materials as well as related methods of using the disclosure electrodes in neural and other monitoring applications.

Abstract: Systems and methods for deploying and securing conductive materials to a region of tissue may utilize a catheter. The catheter may provide a tip with one or more detachable sections or may provide an adjustable opening. A lumen of the catheter may provide a conductive material, such as a filament, fiber, network or patch of carbon nanotubes (CNTs) or carbon nanofibers (CNFs). In some embodiments, the conductive materials may be coupled to securing mechanisms, such as screws, clips, anchors, alligator clips, or anchors with barbs, which can be actuated to attach the conductive materials to desired regions of tissue. In some embodiments, the catheter may provide a needle tip that allows the conductive material to be embedded into desired regions of tissue by inserting the needle into the tissue.

Abstract: Some embodiments of the present disclosure pertain to methods of improving electrical conduction across an impaired region of a tissue (e.g., myocardial tissue) by applying an electrically conductive material (e.g., carbon nanotube fibers) across the impaired region. The electrically conductive materials can become associated with non-impaired regions of the tissue on opposite sides of the impaired region by suturing. Such methods can also be utilized to treat or prevent cardiac arrhythmia in a subject (e.g., ventricular arrhythmia). Additional embodiments of the present disclosure pertain to electrical wirings that include carbon nanotubes, such as carbon nanotube fibers. Such electrical wirings can be used to transmit electrical signals to a tissue or sense electrical signals from the tissue. In some embodiments, the present disclosure also pertains to suture threads that include carbon nanotubes, such as carbon nanotube fibers.

Abstract: In some embodiments, the present disclosure pertains to a device comprising at least one implantable microelectrode. In some embodiments, the implantable microelectrode comprises at least one fiber of aligned carbon nanotubes partially coated with a layer of biocompatible insulating material. In some embodiment of the present disclosure, at least one end of the fiber of aligned carbon nanotubes is uncoated. In some embodiments, the uncoated end of the fiber is electrically active. In some embodiments, the device further comprises a removable inserting device attached to the implantable microelectrode. In some embodiments, the present disclosure pertains to a method of implanting an implantable microelectrode into a subject. In some embodiments, the present disclosure relates to a method of fabricating an implantable microelectrode.