Patents by Inventor Flavio Di Francesco

Flavio Di Francesco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genomic data mining using clustering logic and filtering criteria
    Patent number: 7587280
    Abstract: A method for automatic analysis of genomic information in order to determine relationships among genes allows one to determine complex relationships among genes. First a clustering algorithm is chosen and is applied to the table, obtaining sub-tables of data relative to groups of genes that satisfy the chosen clustering criterion. Therefore, all possible combinations of pair of sub-tables are generated and characteristic parameters are calculated for genes contained in these sub-tables. Finally, for each combination a characteristic value is calculated with a decision algorithm defined in function of these parameters, by considering the genes of the combination as constituting a “Gene Network” if this characteristic value exceeds a pre-defined threshold. The method is preferably is implemented by a relative system of identification of groups of co-expressed and co-regulated genes comprising an intelligent fuzzy sub-system trained off-line identified by a neural network.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: September 8, 2009
    Assignee: STMicroelectronics S.r.l.
    Inventors: Enrico Alessi, Salvatore Oliveri, Flavio Di Francesco, Antonella Licciardello
  • Method of analysis of a table of data relating to gene expression and relative identification system of co-expressed and co-regulated groups of genes
    Publication number: 20040191804
    Abstract: A method for automatic analysis of genomic information in order to determine relationships among genes allows one to determine complex relationships among genes. First a clustering algorithm is chosen and is applied to the table, obtaining sub-tables of data relative to groups of genes that satisfy the chosen clustering criterion. Therefore, all possible combinations of pair of sub-tables are generated and characteristic parameters are calculated for genes contained in these sub-tables. Finally, for each combination a characteristic value is calculated with a decision algorithm defined in function of these parameters, by considering the genes of the combination as constituting a “Gene Network” if this characteristic value exceeds a pre-defined threshold. The method is preferably is implemented by a relative system of identification of groups of co-expressed and co-regulated genes comprising an intelligent fuzzy sub-system trained off-line identified by a neural network.
    Type: Application
    Filed: November 26, 2003
    Publication date: September 30, 2004
    Inventors: Enrico Alessi, Salvatore Oliveri, Flavio Di Francesco, Antonella Licciardello