Patents by Inventor Flavio Somenzi

Flavio Somenzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of symmetrical diacylhydrazines
    Patent number: 6444848
    Abstract: Process for the preparation of symmetrical diacylhydrazines having general formula (I): R1—CO—NH—NH—CO—R1 wherein R1 represents a linear or branched C1-C18 alkyl group; a linear or branched C2-C8 alkoxyalkyl group; a C2-C8 cyanoalkyl group; a C5-C8 cycloalkyl group, said cycloalkyl group optionally containing a heteroatom selected from oxygen, nitrogen and sulfur; a C6-C18 aryl group; a C7C20 arylalkyl group or alkylaryl group, said arylalkyl or alkylaryl groups optionally substituted with one or more hydroxyl groups, or with one or more linear or branched C1-C8 alkoxyl groups; comprising: (a) reacting an ester of a carboxylic acid having general formula (II): R1—CO—OR2 wherein R1 has the same meanings defined above and R2 represents a linear or branched C1-C18 alkyl group, with hydrazine, in its pure or hydrated state, obtaining a monoacylhydrazine having general formula (III): R1—CO—NH—NH2; (b) reacting the monoacylhydrazine having general formula
    Type: Grant
    Filed: March 9, 2001
    Date of Patent: September 3, 2002
    Assignee: Great Lakes Chemical (Europe) GmbH
    Inventors: Fabio Broussard, Carlo Neri, Flavio Somenzi
  • Analogues of the active metabolite of leflunomide
    Patent number: 5905090
    Abstract: Analogues of the active metabolite of leflunomide, and to the use thereof as immunosuppressive and/or antinflammatory agents.
    Type: Grant
    Filed: April 29, 1998
    Date of Patent: May 18, 1999
    Assignee: Italfarmaco S.p.A.
    Inventors: Giorgio Bertolini, Mauro Biffi, Flavio Leoni, Maria Letizia Marchetti, Jacques Mizrahi, Flavio Somenzi, Paolo Mascagni