Patents by Inventor Florence Djedaini-Pilard

Florence Djedaini-Pilard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050085444
    Abstract: The invention relates to the use of dimethylated ?-cyclodextrins, particularly DIMEB and RAMEB, as agents for promoting the penetration of vitamin A or its cosmetically or dermatologically acceptable esters into the epidermis, and their retention in the skin, for the preparation of a cosmetic or dermatological composition containing a combination of vitamin A or at least one of its cosmetically or dermatologically acceptable esters with said dimethylated ?-cyclodextrins. It further relates to novel cosmetic or dermatological compositions containing these combinations of dimethylated ?-cyclodextrins and vitamin A or vitamin A esters, particularly in the form of inclusion complexes. It further relates to uses of these compositions in the field of cosmetics or dermatology.
    Type: Application
    Filed: January 31, 2003
    Publication date: April 21, 2005
    Inventors: Jean-Christophe Archambault, Francoise Ouvrard-Baraton, Florence Djedaini-Pilard, Sandrine Weisse
  • Patent number: 6858723
    Abstract: The invention provides cyclodextrin derivatives that may be used to transport hydrophobic molecules for pharmaceutical or cosmetic applications, by forming organised systems in an aqueous medium, alone or with phospholipids. The cyclodextrin derivatives of the present invention have the formula: in which, R1 represents a steroid, R2 represents an alkyl or aryl group, substituted if applicable, R3 represents H or R2, all the R4 represent OR2, or one of the R4 represents —NHCO(CH2)mCONHR1, m is an integer ranging from 1 to 8, and n is equal to 5, 6 or 7.
    Type: Grant
    Filed: April 26, 2000
    Date of Patent: February 22, 2005
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Rachel Auzely-Velty, Bruno Perly, Florence Djedaini-Pilard
  • Patent number: 5993776
    Abstract: The invention relates to radio-pharmaceutical compositions that include an inclusion complex of a cyclodextrin and a radio-halogenated fatty acid.These complexes include a cyclodextrin such as .beta.-cyclodextrin, .gamma.-cyclodextrin and their derivatives, and a radio-halogenated fatty acid, in particular a fatty acid labelled with radioactive iodine such as 16-iodo 3-methyl hexadecanoic acid suitable for the examination of the myocardium by scintigraphy.The cyclodextrin allows the fatty acid to dissolve in aqueous solution without any addition of human blood albumin, while further improving the biodistribution of the fatty acid and its stability to heat.
    Type: Grant
    Filed: May 14, 1997
    Date of Patent: November 30, 1999
    Assignee: CIS bio International
    Inventors: Roberto Pasqualini, Bruno Perly, Laurent Mauclaire, Florence Djedaini-Pilard, Yves Michel
  • Patent number: 5821349
    Abstract: The invention relates to derivatives of cyclodextrins, their preparation and their use for incorporating hydrophobic molecules into organized surfactant systems. These derivatives of cyclodextrins are in accordance with the formula: ##STR1## in which R.sup.1 represents a group protecting an amine function, the R.sup.2, which can be the same or different, represent OH or NH--CH.sub.2 m--NHR.sup.1,m being an integer from 2 to 18 and n is equal to 5, 6 or 7.
    Type: Grant
    Filed: June 7, 1996
    Date of Patent: October 13, 1998
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Florence Djedaini-Pilard, Jing Lin, Bruno Perly
  • Patent number: 5798342
    Abstract: The invention relates to the use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of Ginkgolides.The cyclodextrins used comply with the formula: ##STR1## in which n is equal to 6, 7 or 8 and the R.sup.1, which can be the same or different, represent OH or SR.sup.2 with R.sup.2 representing a group derived from a monosaccharide or an oligosaccharide.The Ginkgolide is preferably Ginkgolide B.
    Type: Grant
    Filed: September 9, 1996
    Date of Patent: August 25, 1998
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Jacques Defaye, Valerie Laine, Florence Djedaini-Pilard, Bruno Perly
  • Patent number: 5760017
    Abstract: The invention relates to novel cyclodextrin derivatives according to formula: ##STR1## in which R.sup.1 represents OH or NH(CH.sub.2).sub.p OH, n is equal to 5, 6 or 7 and p is an integer from 2 to 6, it being possible for the p to be different when one or more of the R.sup.1 represent NH(CH.sub.2).sub.p OH.These derivatives can be used for solubilizing hydrophobic chemical compounds such as active principles in an aqueous medium by the formation of inclusion complexes therewith.
    Type: Grant
    Filed: December 5, 1996
    Date of Patent: June 2, 1998
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Florence Djedaini-Pilard, Nathalie Azaroual-Bellanger, Bruno Perly
  • Patent number: 5760016
    Abstract: The invention relates to the use of mono-3,6-anhydrocyclodextrins for solubilizing a hydrophobic compound and for controlling the purity of an enantiomer.The mono-3,6-anhydrocyclodextrin complies with the following formula: ##STR1## in which n is equal to 5, 6 or 7. Preferably n is equal to 6. The hydrophobic compound can be a steroid such as prednisolone.
    Type: Grant
    Filed: December 9, 1996
    Date of Patent: June 2, 1998
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Florence Djedaini-Pilard, Bruno Perly