Patents by Inventor Florence Margottin

Florence Margottin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human &bgr;TrCP protein
    Patent number: 6730486
    Abstract: The present invention relates to the human &bgr;TrCP protein for the targeting of proteins towards proteasome degradation pathways, which is capable of interacting with the Vpu protein of HIV-1 virus, with the cell proteins I&kgr;B and &bgr;-catenin and with the cell protein Skp1p, to its peptide fragments and to the nucleic acid sequences coding for said protein and its fragments. It further relates to the use of the human &bgr;-TrCP protein or its peptide fragments for the screening of anti-HIV-1 antiviral agents, antitumoral agents and anti-inflammatory agents, to the antiviral agents, antitumoral agents and anti-inflammatory agents, and to the antibodies directed against said protein and its peptide fragments.
    Type: Grant
    Filed: July 28, 2000
    Date of Patent: May 4, 2004
    Assignees: Institut National de la Sante et de la Recherche Medicale, Institut Pasteur
    Inventors: Richard Benarous, Florence Margottin, Hervé Durand, Fernando Arenzana Seisdedos, Mathias Kroll, Jean-Paul Concordet