Abstract: A device for analyzing a gaseous sample including a first housing including a detection assembly housed in the housing including a preconcentrator, a chromatography column and a detector intended to detect the presence of the separated compounds, a sampling assembly including a cartridge that is removable relative to the first housing, a control and processing unit housed in the housing and configured to execute an analysis operating mode capable of generating a first command for the detection assembly to analyze a first gaseous sample, a second command to determine the exceeding of at least one alert threshold and, if an alert threshold is exceeded, a third command for the sampling assembly to take a second gaseous sample.

Abstract: The present invention relates to a method for manufacturing a chromatography column, in particular for a gas phase chromatography, comprising a stationary phase made from a sol. This method comprises the following steps: (a) introducing this sol at the first end of the column, (b) moving said sol towards the second end of the column, so that a sol layer is formed on the internal wall of the column, this layer being able to form a gel on said internal wall, and (c) drying of the gel. The present invention also relates to a capillary column as well as to a microcolumn which may be manufactured according to this method.

Abstract: A device for extraction of at least one analyte contained in a liquid sample, including an extraction and desorption zone of the analyte with a stationary phase as the extraction zone, a liquid supply inlet to the extraction zone, a gas supply inlet to the extraction zone, an evacuation outlet from the extraction zone that will be connected to either a collection tank, or a device for analysis of the analytes, a valve configured to connect the extraction zone to one of the supply inlets, a valve configured to connect the extraction zone to one of the evacuation outlets, a mechanism heating the valve zone such that when the extraction zone is supplied with liquid, evacuation from the extraction zone takes place to the collection tank.

Abstract: A gravimetric detector including a nanoelectronic structure including: a fixed part, at least one part suspended from the fixed part, an excitation device to vibrate the suspended part relative to the fixed part, a detector to detect variations in vibration of the suspended part, and a porous functionalization layer at least partially covering the suspended part, porosity of the functionalization layer being between 3% and 50%.

Abstract: A device for analyzing a gaseous sample including a first housing including a detection assembly housed in the housing including a preconcentrator, a chromatography column and a detector intended to detect the presence of the separated compounds, a sampling assembly including a cartridge that is removable relative to the first housing, a control and processing unit housed in the housing and configured to execute an analysis operating mode capable of generating a first command for the detection assembly to analyze a first gaseous sample, a second command to determine the exceeding of at least one alert threshold and, if an alert threshold is exceeded, a third command for the sampling assembly to take a second gaseous sample.

Abstract: Gas chromatography column comprising a substrate, a channel formed in said substrate, a cover closing said substrate and a stationary phase covering the walls of said channel, wherein said stationary phase is made of SiOxCyHz with x between 1.6 and 1.8, y between 1 and 2.2 and z between 3 and 4, wherein said stationary phase is porous with a porosity of between 10% and 40%.

Abstract: A device for extraction of analytes with aromatic cycles, preferably analytes with aromatic cycles for which the octanol-water partition coefficient is more than 103, the analytes being contained in a liquid phase, the extraction device including a support and an adsorption layer at least partially covering the support, the adsorption layer being porous SiOxCyHz.

Abstract: A gravimetric detector including a nanoelectronic structure including: a fixed part, at least one part suspended from the fixed part, an excitation device to vibrate the suspended part relative to the fixed part, a detector to detect variations in vibration of the suspended part, and a porous functionalization layer at least partially covering the suspended part, porosity of the functionalization layer being between 3% and 50%.

Abstract: The present invention relates to a method for manufacturing a chromatography column, in particular for a gas phase chromatography, comprising a stationary phase made from a sol. This method comprises the following steps: (a) introducing this sol at the first end of the column, (b) moving said sol towards the second end of the column, so that a sol layer is formed on the internal wall of the column, this layer being able to form a gel on said internal wall, and (c) drying of the gel. The present invention also relates to a capillary column as well as to a microcolumn which may be manufactured according to this method.

Abstract: Gas chromatography column comprising a substrate, a channel formed in said substrate, a cover closing said substrate and a stationary phase covering the walls of said channel, wherein said stationary phase is made of SiOxCyHz with x between 1.6 and 1.8, y between 1 and 2.2 and z between 3 and 4, wherein said stationary phase is porous with a porosity of between 10% and 40%.

Abstract: A device for extraction of at least one analyte contained in a liquid sample, including an extraction and desorption zone of the analyte with a stationary phase as the extraction zone, a liquid supply inlet to the extraction zone, a gas supply inlet to the extraction zone, an evacuation outlet from the extraction zone that will be connected to either a collection tank, or a device for analysis of the analytes, a valve configured to connect the extraction zone to one of the supply inlets, a valve configured to connect the extraction zone to one of the evacuation outlets, a mechanism heating the valve zone such that when the extraction zone is supplied with liquid, evacuation from the extraction zone takes place to the collection tank.

Abstract: A microfluidic component comprises at least one channel (2) delineated by a top wall (6) and a bottom wall (3) and two opposite side walls (4, 5). The distance (P) between the top wall (6) and the bottom wall (3) of the channel (2) is greater than or equal to 25 micrometers and first and second sets of nanotubes (9a, 9b) are respectively borne by the two opposite side walls (4, 5) for the component to present a particularly high ratio between the contact surface and the available volume and a limited overall surface size. In addition, the distance between the two opposite side walls (4, 5) is about a few micrometers and preferably comprised between 3 and 5 micrometers.

Abstract: Analysis chip of at least one analyte, said chip comprising at least one analysis spot for recognition and immobilization specific to the analyte; and a reference range (G) comprising several reference spots each arranged on said chip in a defined manner and independently of one another, each reference spot of this range comprising, immobilized on its surface and in a defined proportion P that is different and known for each spot relative to the other reference spots of said range: a probe reference molecule (PRM) permitting recognition and hybridization specifically to a defined target reference molecule (TRM), and/or an inert oligonucleotide molecule (IM) incapable of recognition and hybridization with said PRM, these molecules both being unable to immobilize said analyte or analytes. The method of the invention comprises the use of said chip with its reference range for analysis of said, at least one, analyte.

Abstract: A microfluidic component comprises at least one closed microchannel filled with nanostructures. The microchannel is produced by previously forming an opening delineating a bottom wall and two opposite side walls of the microchannel in a surface of a substrate. The nanostructures filling said microchannel are formed by in situ growth to constitute a layer of metallic catalyst deposited on said side walls and on said wall bottom. The microchannel is closed, before the nanostructures are formed, by sealing a protective cover onto said surface of the substrate. Sealing is obtained by formation of an eutectic compound between a material of the cover and the metal of the catalyst used for in situ growth of the nanostructures and deposited on the surface of the substrate designed to come into contact with the cover.

Abstract: The device for separating biomolecules from a fluid comprises a microfluidic component provided with at least one microchannel having at least one of the walls supporting a plurality of nanotubes or nanowires. The component comprises at least one electrode electrically connected to at least a part of the nanotubes or nanowires and the device comprises means for applying a voltage between the electrode and the fluid. The nanotubes or nanowires are divided into several active areas in which the nanotubes or nanowires have a different density.

Abstract: A microfluidic component comprises at least one closed microchannel filled with nanostructures. The microchannel is produced by previously forming an opening delineating a bottom wall and two opposite side walls of the microchannel in a surface of a substrate. The nanostructures filling said microchannel are formed by in situ growth to constitute a layer of metallic catalyst deposited on said side walls and on said wall bottom. The microchannel is closed, before the nanostructures are formed, by sealing a protective cover onto said surface of the substrate. Sealing is obtained by formation of an eutectic compound between a material of the cover and the metal of the catalyst used for in situ growth of the nanostructures and deposited on the surface of the substrate designed to come into contact with the cover.

Abstract: A microfluidic component comprises at least one channel (2) delineated by a top wall (6) and a bottom wall (3) and two opposite side walls (4, 5). The distance (P) between the top wall (6) and the bottom wall (3) of the channel (2) is greater than or equal to 25 micrometers and first and second sets of nanotubes (9a, 9b) are respectively borne by the two opposite side walls (4, 5) for the component to present a particularly high ratio between the contact surface and the available volume and a limited overall surface size. In addition, the distance between the two opposite side walls (4, 5) is about a few micrometers and preferably comprised between 3 and 5 micrometers.

Abstract: Analysis chip of at least one analyte, said chip comprising at least one analysis spot for recognition and immobilization specific to the analyte; and a reference range (G) comprising several reference spots each arranged on said chip in a defined manner and independently of one another, each reference spot of this range comprising, immobilized on its surface and in a defined proportion P that is different and known for each spot relative to the other reference spots of said range: a probe reference molecule (PRM) permitting recognition and hybridization specifically to a defined target reference molecule (TRM), and/or an inert oligonucleotide molecule (IM) incapable of recognition and hybridization with said PRM, these molecules both being unable to immobilize said analyte or analytes. The method of the invention comprises the use of said chip with its reference range for analysis of said, at least one, analyte.

Abstract: The present invention relates to a method for the displacement of an analyte fluid within a capillary microchannel and to a microfluidic system. In particular, it relates to the field of microfluidics, and especially to microfluidic systems.