Patents by Inventor Florence TOTI

Florence TOTI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12078645
    Abstract: A method and kit for-, in particular, the medical and veterinary field, predicts and/or detects disseminated intravascular coagulation (DIC) in a biological sample.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: September 3, 2024
    Assignees: HÔPITAUX UNIVERSITAIRES DE STRASBOURG, DIAGNOSTICA STAGO
    Inventors: Julie Helms, Florence Toti, Laure Stiel, Laurent Mauvieux, Ferhat Meziani
  • Publication number: 20240288446
    Abstract: The invention relates to an in-vitro process for predicting and/or detecting fibrinolytic insufficiency, preferably associated to pathologies and NETs with/without disseminated intravascular coagulation (DIC), or from a first biological sample comprising measuring the concentration of plasminogen and/or at least one fragment thereof. The invention also relates to a process for determining the efficiency of a treatment of fibrinolytic insufficiency and to plasminogen and pharmaceutical composition comprising plasminogen for use as a drug in the treatment of fibrinolytic insufficiency, preferably associated to septic shock and disseminated intravascular coagulation (DIC).
    Type: Application
    Filed: October 20, 2020
    Publication date: August 29, 2024
    Inventors: Eduardo ANGLES-CANO, Ferhat MEZIANI, Florence TOTI
  • Publication number: 20190011466
    Abstract: Some embodiments relates to a method for predicting and/or detecting disseminated intravascular coagulation (DIC) in a biological sample, and a kit for predicting and/or detecting disseminated intravascular coagulation (DIC) in a biological sample. Some embodiments has application, in particular, in the medical and veterinary field.
    Type: Application
    Filed: January 25, 2017
    Publication date: January 10, 2019
    Inventors: Julie BOISRAMÉ-HELMS, Florence TOTI, Laure STIEL, Laurent MAUVIEUX, Ferhat MEZIANI