Abstract: A method, a device, and a non-transitory storage medium are described in which a monitoring event handling service is provided. The service may include a non-stand-alone core device subscribing to a registration status for an end device with a stand-alone core device. The service may also include the non-stand-alone core device subscribing to a monitoring event service with the stand-alone core device on behalf of another non-stand-alone core network device. The stand-alone core device may monitor an event when the end device is stand-alone registered and may notify the non-stand-alone core device when the event occurs. The service may include the non-stand-alone core device notifying the other non-stand-alone core device when the event occurs.

Abstract: A cell culture plate with a system for lateral diffusion of molecules across a barrier membrane (FIG. 1), comprising a base consisting of two or more flat-bottomed open-topped wells, denominated the reservoir wells, each containing one or more wells of smaller size (diffusion wells), likewise open-topped and sharing the same flat base, characterized in that each of the diffusion wells communicates with the larger reservoir well which houses it via one or several slits located in the lateral wall(s) of the diffusion well(s), and in that each slit is covered by a semipermeable membrane that permits the passage of soluble substances while retaining insoluble particles and cells; and a removable lid. The cells deposited in the diffusion well(s) may interchange their metabolic products with the corresponding reservoir well containing culture medium or other cells.