Abstract: A controller for a laser microdissection system is configured to receive a first image of a sample comprising image tiles stitched together, and a first set of coordinates in a coordinate system of the first image that define a segment to be removed from the sample. A second image of the sample is generated along with a second set of coordinates in a coordinate system of the second image. The laser microdissection system is controlled based on the second set of coordinates to remove the segment. Reference points are determined on the sample visible in the images. Original coordinates are determined corresponding to coordinates of the reference points in the coordinate system of the first image. Target coordinates are determined corresponding to coordinates of the reference points in the coordinate system of the second image. A second set of coordinates are generated based on the original and target coordinates.

Abstract: A controller for a laser microdissection system is configured to receive a user input corresponding to first settings for the laser microdissection system used with a first objective lens, generate second settings for the laser microdissection system used with a second objective lens based on the first settings, and configure the laser microdissection system based on the second settings. At least one characteristic of a first laser beam generated according to the first settings by the laser microdissection system using the first objective lens is the same for a second laser beam generated according to the second settings by the laser microdissection system using the second objective lens. The at least one characteristic influenced by the first objective lens when the laser microdissection system is used with the first objective lens and influenced by the second objective lens when the laser microdissection system is used with the second objective lens.

Abstract: Disclosed is a container treatment device with a transport device for transporting containers along a predetermined transport path, wherein the transport device has at least one transport device for transporting the containers and at least one container treatment device for treating the containers in a predetermined manner, wherein this transport device includes a preferably rotatable carrier, on which a plurality of holding devices for holding at least one container are arranged, these holding devices being movable relative to the carrier in such a way that a distance between two containers immediately following one another on the transport path can be varied, wherein the container-handling device is arranged in such a way that it can handle the containers transported by the transport device.

Abstract: A laser microdissection system includes a microscope having an objective directed at a sample space, and a laser light source for generating a manipulation light beam. The laser microdissection system includes a dissection unit for coupling the manipulation light beam into the microscope, and separating a dissectate from a sample arranged in the sample space by directing the manipulation light beam onto the sample using outline data relating to an outline on the sample surrounding the dissectate. The laser microdissection system includes a well positioning unit for moving a collection arrangement including one well arranged below the sample relative to an optical axis of the objective, where the well captures the dissectate. The laser microdissection system includes a controller for controlling the well positioning unit to move the collection arrangement based on the outline data such that a center of an opening of the well is arranged below the dissectate.

Abstract: Disclosed is a container treatment apparatus, in particular a container sterilisation apparatus, having a plurality of transport devices for transporting a container along a predetermined transport path, at least one of the transport devices having at least one holding device for holding at least one container during container treatment and/or transport along the transport path, the transport device having a rotatable carrier and a plurality of holding elements arranged on this carrier, wherein a holding element in a first sector, in which a container is received, having a height with respect to a perpendicular projection of the transport path which is different from that in a second sector in which a container is dispensed, and wherein a sector in which an at least partial compensation of the height difference of the holding elements takes place lies along a direction of rotation of the carrier after the second sector and before the first sector.

Abstract: A device (1) for producing a photoactive system (10), in particular a deactivated photoactive system (10), characterised by: an imaging device (2) having at least one imaging arrangement (20), wherein the at least one imaging arrangement (20) has a beam passage plane (SE) and an optical axis (O), and the at least one imaging arrangement (20) is designed to generate electromagnetic beams which extend along a beam path and pass through the imaging arrangement (20) on the beam passage plane (SE) and to reflect the electromagnetic beams along the beam path at the photoactive arrangement (11) in order to image, on a first focal plane (B1) of the imaging arrangement (20), an evaluation image of a photoactive arrangement (11) of the photoactive system (10) to be produced, and the electromagnetic beams of the beam path are captured on the first focal plane (B1) in order to capture the evaluation image of the photoactive arrangement (11); and a first holding device (3a) having a first holding plane (Ha), on the first

Abstract: A container treatment apparatus includes a transport apparatus for transporting containers along a predetermined transport path, wherein the transport apparatus has at least one transport device (100) for transporting the containers (100) and at least one container treatment device (150) for treating the container in a predetermined manner, wherein the transport devices include a rotatable carrier on which a plurality of holding elements (40) for holding at least one container is arranged. The container treatment device is arranged to treat the containers transported by the transport device and the holding element is rotatable such that the container held by the holding element is rotatable with respect to its longitudinal direction and the container treatment apparatus includes a monitoring device for monitoring the rotational movement of the containers.

Abstract: Disclosed is a container treatment apparatus and treatment method, in particular a container sterilisation apparatus, having a plurality of transport devices for transporting a container along a predetermined transport path, at least one of the transport devices having at least one holding device for holding at least one container during container treatment and/or transport along the transport path, the transport device having a rotatable carrier and a plurality of holding elements arranged on this carrier, wherein a holding element in a first sector, in which a container is received, having a height with respect to a perpendicular projection of the transport path which is different from that in a second sector in which a container is dispensed, and wherein a sector in which an at least partial compensation of the height difference of the holding elements takes place lies along a direction of rotation of the carrier after the second sector and before the first sector.

Abstract: A container treatment apparatus for transporting plastic preforms along a predetermined transport path includes several transport devices, each of which has at least one holding element for holding a plastic container and guiding the plastic container along a portion of the transport path, wherein a second transport device immediately follows a first transport device along the transport path, and containers are transferred from a holding device of the first transport device to a holding device of the second transport device. The transport path along which the containers can be guided by the first transport device is arranged at least in portions outside a clean room, and the transport path along which the containers can be guided by the first transport device is surrounded at least in part by a radiation shielding device.

Abstract: A method for obtaining dissectates from a microscopic sample using a laser microdissection system having a laser unit includes: a) at least partially circumcising and releasing from the sample dissectate regions of the sample as the dissectates using laser pulses provided by the laser unit; b) transferring the dissectates, by being released from the sample, along dissectate trajectories into receptacles of a dissectate collection unit; and c) positioning the receptacles of a dissectate collection unit using a positioning unit to collect the dissectates. The positioning of the receptacles of the dissectate collection unit using the positioning unit is automatically performed based on estimates of the dissectate trajectories, the estimates of the dissectate trajectories being obtained in a learning mode, the learning mode including obtaining dissectates by repeatedly performing at least steps a) and b). Parameters of the dissectate trajectories are determined for a plurality of dissectates.

Abstract: A method for laser microdissection includes: processing a microscopic examination object by a laser beam using tuples of coordinate values which respectively indicate positions of target points on the examination object at least in a first spatial direction and a second spatial direction orthogonal to the first spatial direction, positions of at least three reference points being ascertained beforehand in each case in the first and second spatial directions and also in a third spatial direction orthogonal to the first and second spatial directions; defining a reference plane based on the positions of the reference points; and determining, for the target points, further coordinate values indicating an expected position of the target points on the examination object in the third spatial direction in each case, as determined further coordinate values, the determining of the further coordinate values being performed depending on the defined reference plane.

Abstract: A sample manipulation device includes a manipulation light source configured to emit manipulation light, an objective configured to focus the manipulating light onto the sample to form a manipulation light beam, a scanning unit configured to move the manipulation light beam within a field of view of the objective, a sample positioning unit configured to move the sample relative to an optical axis of the objective, and a controller configured to receive manipulation data comprising at least one manipulation path, upon determining that the manipulation path is entirely outside the predetermined area, control the manipulation light source and the scanning unit such that the sample is manipulated along the manipulation path, and upon determining that at least a part of the manipulation path is inside the predetermined area, control the sample positioning unit to move the sample such that the manipulation path is entirely outside the predetermined area.

Abstract: Disclosed is a container treatment apparatus and treatment method, in particular a container sterilisation apparatus, having a plurality of transport devices for transporting a container along a predetermined transport path, at least one of the transport devices having at least one holding device for holding at least one container during container treatment and/or transport along the transport path, the transport device having a rotatable carrier and a plurality of holding elements arranged on this carrier, wherein a holding element in a first sector, in which a container is received, having a height with respect to a perpendicular projection of the transport path which is different from that in a second sector in which a container is dispensed, and wherein a sector in which an at least partial compensation of the height difference of the holding elements takes place lies along a direction of rotation of the carrier after the second sector and before the first sector.

Abstract: Disclosed is a container treatment device with a transport device for transporting containers along a predetermined transport path, wherein the transport device has at least one transport device for transporting the containers and at least one container treatment device for treating the containers in a predetermined manner, wherein this transport device includes a preferably rotatable carrier, on which a plurality of holding devices for holding at least one container are arranged, these holding devices being movable relative to the carrier in such a way that a distance between two containers immediately following one another on the transport path can be varied, wherein the container-handling device is arranged in such a way that it can handle the containers transported by the transport device.

Abstract: A container treatment apparatus includes a transport apparatus for transporting containers along a predetermined transport path, wherein the transport apparatus has at least one transport device (100) for transporting the containers (100) and at least one container treatment device (150) for treating the container in a predetermined manner, wherein the transport devices include a rotatable carrier on which a plurality of holding elements (40) for holding at least one container is arranged. The container treatment device is arranged to treat the containers transported by the transport device and the holding element is rotatable such that the container held by the holding element is rotatable with respect to its longitudinal direction and the container treatment apparatus includes a monitoring device for monitoring the rotational movement of the containers.

Abstract: Disclosed is a container treatment apparatus for transporting plastic containers and in particular plastic preforms along a predetermined transport path, wherein the container treatment apparatus has at least one transport device having a plurality of holding elements, wherein the transport device is a pitch distribution starwheel having a movement device configured to allow movement of the holding elements in at least two planes.

Abstract: Disclosed is a container treatment apparatus, in particular a container sterilisation apparatus, having a plurality of transport devices for transporting a container along a predetermined transport path, at least one of the transport devices having at least one holding device for holding at least one container during container treatment and/or transport along the transport path , the transport device having a rotatable carrier and a plurality of holding elements arranged on this carrier, wherein a holding element in a first sector, in which a container is received, having a height with respect to a perpendicular projection of the transport path which is different from that in a second sector in which a container is dispensed, and wherein a sector in which an at least partial compensation of the height difference of the holding elements takes place lies along a direction of rotation of the carrier after the second sector and before the first sector.

Abstract: A device (1) for producing a photoactive system (10), in particular a deactivated photoactive system (10), characterised by: an imaging device (2) having at least one imaging arrangement (20), wherein the at least one imaging arrangement (20) has a beam passage plane (SE) and an optical axis (O), and the at least one imaging arrangement (20) is designed to generate electromagnetic beams which extend along a beam path and pass through the imaging arrangement (20) on the beam passage plane (SE) and to reflect the electromagnetic beams along the beam path at the photoactive arrangement (11) in order to image, on a first focal plane (B1) of the imaging arrangement (20), an evaluation image of a photoactive arrangement (11) of the photoactive system (10) to be produced, and the electromagnetic beams of the beam path are captured on the first focal plane (B1) in order to capture the evaluation image of the photoactive arrangement (11); and a first holding device (3a) having a first holding plane (Ha), on the first

Abstract: A method for obtaining dissectates from a microscopic sample using a laser microdissection system having a laser unit includes: a) at least partially circumcising and releasing from the sample dissectate regions of the sample as the dissectates using laser pulses provided by the laser unit; b) transferring the dissectates, by being released from the sample, along dissectate trajectories into receptacles of a dissectate collection unit; and c) positioning the receptacles of a dissectate collection unit using a positioning unit to collect the dissectates. The positioning of the receptacles of the dissectate collection unit using the positioning unit is automatically performed based on estimates of the dissectate trajectories, the estimates of the dissectate trajectories being obtained in a learning mode, the learning mode including obtaining dissectates by repeatedly performing at least steps a) and b). Parameters of the dissectate trajectories are determined for a plurality of dissectates.

Abstract: A method for laser microdissection includes: processing a microscopic examination object by a laser beam using tuples of coordinate values which respectively indicate positions of target points on the examination object at least in a first spatial direction and a second spatial direction orthogonal to the first spatial direction, positions of at least three reference points being ascertained beforehand in each case in the first and second spatial directions and also in a third spatial direction orthogonal to the first and second spatial directions; defining a reference plane based on the positions of the reference points; and determining, for the target points, further coordinate values indicating an expected position of the target points on the examination object in the third spatial direction in each case, as determined further coordinate values, the determining of the further coordinate values being performed depending on the defined reference plane.