Abstract: A collapsible or folding saw is provided as a compact hand tool that when folded covers and protects the blade. The folding saw is movable between an extended useable condition and a folded condition. The saw comprises a frame having a longitudinal telescoping upper member, and first and second collapsible side supports depending from the upper member. A blade is coupled between the first and second collapsible side supports, whereby a tensioning mechanism is provided to tension the blade. Further, a handle is provided having a first portion pivotably coupled to the frame and wherein the handle pivots between a first condition to form a free-end handle and a second handle condition where the handle engages the upper member and encapsulates the blade.

Abstract: The present invention provides a pharmaceutical formulation prepared as dry syrups representing mere powder mixtures of beta-lactam antibiotics as active pharmaceutical ingredients and excipients without applying any other process steps than simple mixing of dry powder, whereby the pharmaceutical formulation combines two essential properties for processability and dosability: good flowability and high stability against segregation.

Abstract: The invention relates to a transport vehicle having variable width and track width, a chassis (14) and at least one steering axle (16, 18, 20, 22), wherein the chassis (14) comprises two chassis parts (28) each carrying a row of bogies (60) arranged one after the other and are adjustable transverse to a vertical longitudinal medium plane (26) of the transport vehicle. According to the invention only a single longitudinally adjustable transverse track rod (72) is arranged between the two rows of bogies (60) connecting two bogies (60) of the one or the other steering axle (16, 18, 20, 22) and which length is adjustable according to a degree of enlargement or reduction of the width and track width.

Abstract: The present invention provides a pharmaceutical formulation prepared as dry syrups representing mere powder mixtures of beta-lactam antibiotics as active pharmaceutical ingredients and excipients without applying any other process steps than simple mixing of dry powder, whereby the pharmaceutical formulation combines two essential properties for processability and dosability: good flowability and high stability against segregation.

Abstract: The invention relates to a heavy-load transport vehicle (10) for transporting an elongated object, having a tractor (14), a multi-axle trailer (16) and a carrier (18) for the elongated object supported on the trailer and on the tractor (14), wherein the trailer (16) and the carrier (18) are rotatable in relation to each other about a vertical axis (52) of the transport vehicle (10). According to the invention the carrier is supported on the tractor (14) via a goose-neck (22), the trailer (16) has at least one rigid axle (42, 44) and at least one steering axle (40), and in a steering operation mode during the journey, the steering axle (40) of the trailer (16) is steerable in relation to the trailer (16) about the vertical axis (52) as a function of the rotational movements of the carrier (18).

Abstract: The invention relates to a transport vehicle having variable width and track width, a chassis (14) and at least one steering axle (16, 18, 20, 22), wherein the chassis (14) comprises two chassis parts (28) each carrying a row of bogies (60) arranged one after the other and are adjustable transverse to a vertical longitudinal medium plane (26) of the transport vehicle. According to the invention only a single longitudinally adjustable transverse track rod (72) is arranged between the two rows of bogies (60) connecting two bogies (60) of the one or the other steering axle (16, 18, 20, 22) and which length is adjustable according to a degree of enlargement or reduction of the width and track width.

Abstract: The invention relates to a method for identifying T-cell stimulating protein fragments using the following steps: a) detecting the amino acid sequence of an antigen; b) subdividing the found amino acid sequence of the antigen into protein fragments; c) synthesizing at least one protein fragment; d) incubating a suspension containing t-cells with the protein fragments; e) identifying an induced T-cell cytokine or activation marker by flow-through cytometry, and; f) assigning the T-cells, with which T-cell cytokines and/or activation markers were identified, to the protein fragments which were incubated with the T-cells. The corresponding protein fragments/peptides are synthetically produced with the assistance of the detected positive sequence, and said corresponding protein fragments/peptides can be utilized to produce a medicament for immunostimulation.

Abstract: The present invention relates to peptides or pretide derivatives of the 65kD lower matrix phosphoprotein of human cytomegalovirus. The peptides disclosed are useful for determining whether subjects have een exposed to human cytomegalovirus. Methods for using these peptides or derivatives thereof to determine the peptide-induced production of interferon-? and/or TNF-? in CD8+ T cells isolated from subjects are also disclosed.

Abstract: The invention relates to a method for the antigen-specific stimulation of T-lymphocytes with a synthetic peptide library, by preparing a plurality of peptides, each of said peptides comprising a fragment less than the whole of the total amino acid sequence of the antigen, each of said peptides being a minimum of 9 amino acid residues (AAs) in length, and the amino acid sequence of each peptide overlapping with the amino acid sequence of at least one other of said peptides; combining a plurality of the peptides from a) into a peptide library, said peptide library comprises a plurality of the peptides selected such that their collective overlapping amino acid sequences span the total amino acid sequence of the antigen; and incubating a suspension comprising CD8+ T lymphocytes, CD4+ T lymphocytes or a mixture of CD8+ and CD4+ with said peptide library in a single culture run.

Abstract: The present invention relates to peptides or pretide derivatives of the 65 kD lower matrix phosphoprotein of human cytomegalovirus. The peptides disclosed are useful for determining whether subjects have een exposed to human cytomegalovirus. Methods for using these peptides or derivatives thereof to determine the peptide-induced production of interferon-? and/or TNF-? in CD8+ T cells isolated from subjects are also disclosed.

Abstract: The present invention relates to peptides or peptide derivatives of the 65 kD lower matrix phoshpoprotein of human cytomegalovirus. The peptides disclosed are useful for determining whether subjects have been exposed to human cytomegalovirus. Methods for using these peptides or derivatives thereof to determine the peptide-induced production of interferon-? and/or TNF-? in CD8+ T cells isolated from subjects are also disclosed.

Abstract: The invention relates to a method for the antigen-specific stimulation of T-lymphocytes with synthetic peptide libraries, comprising the following steps: a) dividing the whole amino acid sequence of the antigen into protein fragments with partial amino acid sequences: b) synthesising a peptide library containing these protein fragments: c) incubating a suspension containing CD8− and/or CD4− T-lymphocytes with all of the protein fragments of the peptide library in a single culture batch. The method can be used for immunostimulation of T-lymphocytes of mammals, especially humans, as well as for diagnosis purposes, in order to determine whether a mammal, especially a human being, has previously responded to a specific protein with its/his/her immune system, and the strength of this response.