Abstract: A computer-assisted method for compensating for position-dependent density fluctuations in printing nozzles of inkjet printing heads in an inkjet printing machine includes implementing pre-compensation for all color separations of a print image during the halftoning process in the pre-print department on the basis of a pre-defined density compensation profile by using a pre-print computer. Online compensation is implemented for all color separations of the now pre-compensated print image during an on-going production run for producing the print image on the basis of a re-calculated density compensation profile by using a control unit of the inkjet printing machine.