Patents by Inventor Florian KOLLING

Florian KOLLING has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted [1,2,4]triazolo[4,3-A]pyrazines as prolyl endopeptidase inhibitors
    Patent number: 11337973
    Abstract: The invention relates to prolyl endopeptidase (PREP) inhibitors of formula (I) which contain a condensed 2,4-dihydro-3H-1,2,4-triazol-3-one ring system, methods for producing same, the use thereof alone or in combinations for treating and/or preventing diseases, and the use thereof for producing drugs for treating and/or preventing diseases, in particular for treating and/or preventing inflammatory lung diseases (COPD).
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: May 24, 2022
    Assignees: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft
    Inventors: Nicole Biber, Damian Brockschnieder, Florian Kölling, Jörg Meding, Hideki Miyatake Ondozabal, Thomas Neubauer, Martina Schäfer, Dmitry Zubov, Carsten Terjung
  • SUBSTITUTED 2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONES AND USE OF SAME
    Publication number: 20200375986
    Abstract: The invention relates to prolyl endopeptidase (PREP) inhibitors which contain a condensed 2,4-dihydro-3H-1,2,4-triazol-3-one ring system, methods for producing same, the use thereof alone or in combinations for treating and/or preventing diseases, and the use thereof for producing drugs for treating and/or preventing diseases, in particular for treating and/or preventing inflammatory lung diseases (COPD).
    Type: Application
    Filed: October 31, 2018
    Publication date: December 3, 2020
    Applicants: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft
    Inventors: Nicole BIBER, Damian BROCKSCHNIEDER, Florian KÖLLING, Jörg MEDING, Hideki MIYATAKE ONDOZABAL, Thomas NEUBAUER, Martina SCHÄFER, Dmitry ZUBOV, Carsten TERJUNG
  • Substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-A]pyridine-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo[2,1-C][1,2,4]triazol-3-ones, and use thereof
    Patent number: 10722501
    Abstract: The present application relates to novel substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo[2,1-c][1,2,4]triazol-3-ones of formula (I), to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of lung inflammation disorders.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: July 28, 2020
    Assignees: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Nicole Biber, Damian Brockschnieder, Kersten Matthias Gericke, Florian Kölling, Klemens Lustig, Jörg Meding, Heinrich Meier, Thomas Neubauer, Martina Schäfer, Andreas Timmermann, Dmitry Zubov, Carsten Terjung, Niels Lindner, Volker Badock, Dieter Moosmayer, Hideki Miyatake Ondozabal, Stephen Moore, Alexander Schulz
  • SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF
    Publication number: 20190160048
    Abstract: The present application relates to novel substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo[2,1-c][1,2,4]triazol-3-ones, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of lung inflammation disorders.
    Type: Application
    Filed: May 8, 2017
    Publication date: May 30, 2019
    Applicants: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Nicole BIBER, Damian BROCKSCHNIEDER, Kersten Matthias GERICKE, Florian KÖLLING, Klemens LUSTIG, Jörg MEDING, Heinrich MEIER, Thomas NEUBAUER, Martina SCHÄFER, Andreas TIMMERMANN, Dmitry ZUBOV, Carsten TERJUNG, Niels LINDNER, Volker BADOCK, Dieter MOOSMAYER, Hideki MIYATAKE ONDOZABAL, Steven MOORE, Alexander SCHULZ
  • HYDROXYALKYL-SUBSTITUTED PHENYLTRIAZOLE DERIVATIVES AND USES THEREOF
    Publication number: 20170313665
    Abstract: The present invention relates to novel 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular and renal diseases.
    Type: Application
    Filed: October 30, 2015
    Publication date: November 2, 2017
    Inventors: Carsten SCHMECK, Michael GERISCH, Nils GRIEBENOW, Peter KOLKHOF, Florian KÖLLING, Anna ENGELEN, Axel KRETSCHMER, Dieter LANG, Klemens LUSTIG, Thomas MONDRITZKI, Elisabeth POOK, Hartmut BECK, Frank SÜßMEIER, Sonja VOLLMER, Pierre WASNAIRE
  • Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof
    Patent number: 9771352
    Abstract: The present invention relates to novel 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular and renal diseases.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: September 26, 2017
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Carsten Schmeck, Michael Gerisch, Nils Griebenow, Peter Kolkhof, Florian Kölling, Anna Engelen, Axel Kretschmer, Dieter Lang, Klemens Lustig, Thomas Mondritzki, Elisabeth Pook, Hartmut Beck, Frank Süβmeier, Sonja Vollmer, Pierre Wasnaire
  • Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof
    Publication number: 20160122325
    Abstract: The present invention relates to novel 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular and renal diseases.
    Type: Application
    Filed: November 2, 2015
    Publication date: May 5, 2016
    Inventors: Carsten SCHMECK, Michael GERISCH, Nils GRIEBENOW, Peter KOLKHOF, Florian KOLLING, Anna ENGELEN, Axel KRETSCHMER, Dieter LANG, Klemens LUSTIG, Thomas MONDRITZKI, Elisabeth POOK, Hartmut BECK, Frank SÜßMEIER, Sonja VOLLMER, Pierre WASNAIRE