Abstract: Method of generating vibrations in an electric vehicle and electric vehicle thereof. The method being executed by a controller of the electric vehicle. The method includes providing a signal for operating the electric motor and selecting one of a first driver-contacting component or a second driver-contacting component to be vibrated. The method continues with adjusting the signal for causing vibration of the electric motor at a desired frequency. The desired frequency is at or near a resonance frequency of one of the first or the second driver-contacting components. The method continues with applying the adjusted signal to the electric motor.

Abstract: The present invention relates to a compound which comprises or consists of (a) a reactive moiety, said reactive moiety being capable of reacting with a functional group of a peptide to form a covalent bond; and covalently joined thereto (b) a moiety which fragments in the mass spectrometer (i) at an energy below the energy required for fragmenting peptides and/or a higher conversion rate than peptides; and (ii) at said energy according to (i) and when coupled to a peptide via said reactive group, at a single site within said compound coupled to a peptide, to yield a first moiety and a second moiety, said second moiety being coupled to said peptide.

Abstract: This invention generally relates to the field of somatic gene therapy by using viral vectors, and in particular adeno-associated virus (AAV) vectors for the treatment of inherited or acquired diseases. More specifically, the invention relates to a viral capsid protein that provide for a specific transduction of murine endothelial cells for treating or preventing a heart disease in a primate. The viral capsid protein was found to specifically bind to primate heart tissue cells, and in particular primate heart muscle cells, and can be used to provide for an efficient and selective transduction of primate cardiomyocytes and ensure heart tissue-specific expression of one or more transgenes in the primate. The invention further relates to a recombinant viral vector, preferably an AAV vector, which comprises a capsid with at least one transgene packaged in the capsid. The viral vector is suitable for the therapeutic treatment of a cardiac disorder or disease in a primate.

Abstract: The present invention relates to use of an isobaric label in mass spectrometry (MS) analysis using data-independent acquisition (DIA), wherein said isobaric label comprises or consists of a group which fragments in the mass spectrometer (i) at an energy below the energy required for fragmenting analyte-derived precursor ions and/or a higher conversion rate than said precursor ions; and (ii) at said energy according to (i) and when coupled to a precursor ion, at a single site within said group, to yield a first moiety and a second moiety, said second moiety being coupled to said precursor ion.

Abstract: A system for keyless activation, engagement, and monitoring of vehicles and mobile app system and methods of use via the Internet is provided. The system may include a group of devices having a processor and a data store that are connected to a network. Any one of a first, second, and/or third computing devices may be configured to transmit, receive and process at least one vehicle activation command associated with a first vehicle via a close proximity wireless communication. Additionally, a fourth computing device may be configured to electrically communicate with any of the first, second, and/or third computing device so as to control the first, second, and/or third computing device. An associated method is also provided.

Abstract: The present invention relates to use of an isobaric label in mass spectrometry (MS) analysis using data-independent acquisition (DIA), wherein said isobaric label comprises or consists of a group which fragments in the mass spectrometer (i) at an energy below the energy required for fragmenting analyte-derived precursor ions and/or a higher conversion rate than said precursor ions; and (ii) at said energy according to (i) and when coupled to a precursor ion, at a single site within said group, to yield a first moiety and a second moiety, said second moiety being coupled to said precursor ion.

Abstract: The present invention relates to a compound which comprises or consists of (a) a reactive moiety, said reactive moiety being capable of reacting with a functional group of a peptide to form a covalent bond; and covalently joined thereto (b) a moiety which fragments in the mass spectrometer (i) at an energy below the energy required for fragmenting peptides and/or a higher conversion rate than peptides; and (ii) at said energy according to (i) and when coupled to a peptide via said reactive group, at a single site within said compound coupled to a peptide, to yield a first moiety and a second moiety, said second moiety being coupled to said peptide.

Abstract: A system for keyless activation, engagement, and monitoring of vehicles and mobile app system and methods of use via the Internet is provided. The system may include a group of devices having a processor and a data store that are connected to a network. Any one of a first, second, and/or third computing devices may be configured to transmit, receive and process at least one vehicle activation command associated with a first vehicle via a close proximity wireless communication. Additionally, a fourth computing device may be configured to electrically communicate with any of the first, second, and/or third computing device so as to control the first, second, and/or third computing device. An associated method is also provided.

Abstract: A system for keyless activation, engagement, and monitoring of vehicles and mobile app system and methods of use via the Internet is provided. The system may include a group of devices having a processor and a data store that are connected to a network. Any one of a first, second, and/or third computing devices may be configured to transmit, receive and process at least one vehicle activation command associated with a first vehicle via a close proximity wireless communication. Additionally, a fourth computing device may be configured to electrically communicate with any of the first, second, and/or third computing device so as to control the first, second, and/or third computing device. An associated method is also provided.

Abstract: A system for keyless activation, engagement, and monitoring of vehicles and mobile app system and methods of use via the Internet is provided. The system may include a group of devices having a processor and a data store that are connected to a network. Any one of a first, second, and/or third computing devices may be configured to transmit, receive and process at least one vehicle activation command associated with a first vehicle via a close proximity wireless communication. Additionally, a fourth computing device may be configured to electrically communicate with any of the first, second, and/or third computing device so as to control the first, second, and/or third computing device. An associated method is also provided.

Abstract: An apparatus for electrically triggering water discharge is connected to an operating plate (1) and a sensor (31) that is arranged in a rearwards region. The operating plate (1) is transparent or translucent for human visible and infrared light wavelengths and provides at least one indication surface region (42, 43). The indication surface region has a partially transmissive coating (22, 23), behind which are one or more light sources (10, 11) emitting light that is visible to the human eye. At least one signal-transmitter surface region (21) is provided with a coating that is non-transmissive for light that is visible to the human eye and is transparent or translucent for infrared wavelengths, behind which light sources (20), which emit one or more infrared wavelengths, are arranged.

Abstract: An actuating and display plate for a flushing device consists of a non-conductive transparent material, wherein the plate has at least one viewing window, behind which are disposed: an infrared light source, a proximity sensor, which works on a light-reflection basis and is sensitive to the wavelength zone and with which the flushing device can be triggered, and a display light source within the visible light zone. On the plate is provided a back coating, which has a transmission in the range between 2 percent and 15 percent for the visible light zone (22) and a transmission of more than 60 percent for the near-infrared light zone (24).

Abstract: An apparatus for electrically triggering water discharge is connected to an operating plate (1) and a sensor (31). The sensor (31) is arranged in the rearwards region, when viewed by a user triggering the water discharge, behind the operating plate (1). The operating plate (1) is a plate (1) which is transparent or translucent for light wavelengths which are visible to the human eye and for near-infrared wavelengths, and provides at least one indication surface region (42, 43) on the side that is remote from the user, whereas said indication surface region is provided with a partially transmissive coating (22, 23), behind which one or more light sources (10, 11) emitting light that is visible to the human eye are arranged.