Patents by Inventor Florian PUENNER

Florian PUENNER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic compound
    Patent number: 12723028
    Abstract: The present invention provides a compound having a glucosylceramide synthase inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of lysosomal storage diseases (e.g., Gaucher's disease, Fabry's disease, GM1-gangliosidosis, GM2 activator deficiency, Tay-Sachs disease, Sandhoffs disease), neurodegenerative diseases (e.g., Parkinson's disease, Lewy body dementia, multiple-system atrophy) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: September 1, 2026
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Yuta Tanaka, Yuta Tanaka, Keiko Kakegawa, Takahito Kasahara, Fumiaki Kikuchi, Takeshi Yamamoto, Tomohiro Ohashi, Zenichi Ikeda, Florian Puenner, Minoru Nakamura, Kazuaki Takami, Masataka Murakami, Masaki Daini, Masaki Seto, Satoshi Mikami, Minoru Sasaki
  • Heterocyclic compounds as antagonist of NMDA
    Patent number: 12637418
    Abstract: A heterocyclic compound that can have an antagonistic action on an NMDA receptor containing the NR2B subunit, and is expected to be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like is provided. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.
    Type: Grant
    Filed: January 23, 2020
    Date of Patent: May 26, 2026
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Yuya Oguro, Makoto Kamata, Satoshi Mikami, Shinji Morimoto, Sachie Takashima, Masaki Daini, Osamu Kubo, Fumiaki Kikuchi, Akinori Toita, Florian Puenner, Takahito Kasahara, Masataka Murakami, Shuhei Ikeda, Fumie Yamaguchi, Minoru Nakamura, Takafumi Yukawa
  • Heterocyclic compound
    Patent number: 12528802
    Abstract: The present invention provides a compound having a glucosylceramide synthase inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of lysosomal storage diseases (e.g., Gaucher's disease, Fabry's disease, GM1-gangliosidosis, GM2 activator deficiency, Tay-Sachs disease, Sandhoffs disease), neurodegenerative diseases (e.g., Parkinson's disease, Lewy body dementia, multiple-system atrophy) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: January 20, 2026
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Yuta Tanaka, Yuta Tanaka, Fumiaki Kikuchi, Takeshi Yamamoto, Minoru Nakamura, Kazuaki Takami, Masataka Murakami, Masaki Daini, Yasufumi Wada, Keiko Kakegawa, Takahito Kasahara, Tomohiro Ohashi, Junsi Wang, Zenichi Ikeda, Florian Puenner, Masaki Seto, Satoshi Mikami, Minoru Sasaki
  • HETEROCYCLIC COMPOUND
    Publication number: 20220289679
    Abstract: The present invention provides a compound having a glucosylceramide synthase inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of lysosomal storage diseases (e.g., Gaucher's disease, Fabry's disease, GM1-gangliosidosis, GM2 activator deficiency, Tay-Sachs disease, Sandhoffs disease), neurodegenerative diseases (e.g., Parkinson's disease, Lewy body dementia, multiple-system atrophy) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.
    Type: Application
    Filed: July 28, 2020
    Publication date: September 15, 2022
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Yuta TANAKA, Yuta TANAKA, Keiko KAKEGAWA, Takahito KASAHARA, Fumiaki KIKUCHI, Takeshi YAMAMOTO, Tomohiro OHASHI, Zenichi IKEDA, Florian PUENNER, Minoru NAKAMURA, Kazuaki TAKAMI, Masataka MURAKAMI, Masaki DAINI, Masaki SETO, Satoshi MIKAMI, Minoru SASAKI
  • HETEROCYCLIC COMPOUND
    Publication number: 20220274982
    Abstract: The present invention provides a compound having a glucosylceramide synthase inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of lysosomal storage diseases (e.g., Gaucher's disease, Fabry's disease, GM1-gangliosidosis, GM2 activator deficiency, Tay-Sachs disease, Sandhoffs disease), neurodegenerative diseases (e.g., Parkinson's disease, Lewy body dementia, multiple-system atrophy) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.
    Type: Application
    Filed: July 28, 2020
    Publication date: September 1, 2022
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Yuta TANAKA, Yuta TANAKA, Fumiaki KIKUCHI, Takeshi YAMAMOTO, Minoru NAKAMURA, Kazuaki TAKAMI, Masataka MURAKAMI, Masaki DAINI, Yasufumi WADA, Keiko KAKEGAWA, Takahito KASAHARA, Tomohiro OHASHI, Junsi WANG, Zenichi IKEDA, Florian PUENNER, Masaki SETO, Satoshi MIKAMI, Minoru SASAKI
  • HETEROCYCLIC COMPOUND AND USE THEREOF
    Publication number: 20220089525
    Abstract: A heterocyclic compound that can have an antagonistic action on an NMDA receptor containing the NR2B subunit, and is expected to be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like is provided. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.
    Type: Application
    Filed: January 23, 2020
    Publication date: March 24, 2022
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Yuya OGURO, Makoto KAMATA, Satoshi MIKAMI, Shinji MORIMOTO, Sachie TAKASHIMA, Masaki DAINI, Osamu KUBO, Fumiaki KIKUCHI, Akinori TOITA, Florian PUENNER, Takahito KASAHARA, Masataka MURAKAMI, Shuhei IKEDA, Fumie YAMAGUCHI, Minoru NAKAMURA, Takafumi YUKAWA