Patents by Inventor Florian Solzbacher

Florian Solzbacher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230064374
    Abstract: An apparatus includes a flexible, electrically conducting layer disposed between a first flexible electrically insulating layer and a second flexible electrically insulating layer. At least one of the first electrically insulating layer, the electrically conducting layer, or the second electrically insulating layer includes multiple recesses defined therein, the recesses collectively having a predefined pattern. The apparatus also includes protrusions in the form of penetrating beam structures capable of accessing deep tissue structures, and at least one electrical access site electrically coupled to the electrically conducting layer, forming an electrode site. The apparatus also includes microelectronic circuitry/coils and components to serve as an implantable, flexible, conformally adjustable, interface for stimulating and/or recording electrical activity in biological tissue.
    Type: Application
    Filed: August 30, 2022
    Publication date: March 2, 2023
    Inventors: Moritz Michael LEBER, Florian SOLZBACHER, Ken SHEPARD
  • Publication number: 20220370805
    Abstract: The present disclosure provides systems and methods related to electroencephalography (EEG) electrode arrays. In particular, the present disclosure provides systems and methods relating to the manufacture and use of high-resolution electrocorticography (ECOG) electrode arrays and stereoelectroencephalography (SEEG) electrode arrays having various combinations and arrangements of microelectrodes and macroelectrodes for recording and modulating nervous system activity.
    Type: Application
    Filed: September 18, 2020
    Publication date: November 24, 2022
    Inventors: Gregory Cogan, Jonathan Viventi, Nandan Lad, Bijan Pesaran, Virginia Woods, Chia-Han Chiang, Charles Wang, Katrina Barth, Werner Doyle, Patricia Dugan, Orrin Devinsky, Sasha Devore, Daniel Friedman, Amy Orsborn, Florian Solzbacher, Robert Franklin, Sandeep Negi, Saket Mulge
  • Patent number: 11445997
    Abstract: Systems and methods for accurately measuring changes in biomarker sensitive hydrogel volume and shape due to exposure to various biomarkers include a system for identifying one or more dimensional changes in a biomarker sensitive hydrogel positioned within an in vivo environment. The system includes a biomarker sensitive hydrogel positioned within an in vivo environment and configured to dimensionally change in response to interaction with predefined biomarkers. The system additionally includes an ultrasound transducer for locating and identifying one or more characteristics of the biomarker sensitive hydrogel and a computer system in electrical communication with the ultrasound transducer. The computer system is configured to receive characteristics of the biomarker sensitive hydrogel from the ultrasound transducer and determine dimensional changes of the biomarker sensitive hydrogel based on the received characteristics.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: September 20, 2022
    Assignees: UNIVERSITY OF UTAH RESEARCH FOUNDATION, SENTIOMED, INC.
    Inventors: Mahender nath Avula, Douglas A. Christensen, Navid Farhoudi, Stan Kanarowski, Julia Koerner, Jules John Magda, Rami Sami Marrouche, Christopher F. Reiche, Florian Solzbacher, Michael David Sorenson
  • Publication number: 20210380400
    Abstract: A membrane based microelectronic device (200) can include a printed circuit board (202), a polymer film (210) laminated onto the circuit board, and one or more microelectromechanical components (208) integrated into the printed circuit board (202). At least a portion of the polymer film (210) forms a membrane element of the one or more microelectromechanical components (208).
    Type: Application
    Filed: September 19, 2019
    Publication date: December 9, 2021
    Inventors: Moritz Leber, Florian Solzbacher, Brian Baker
  • Publication number: 20210338195
    Abstract: Microresonator structures including a top polymer film layer, a bottom polymer film layer, and a smart hydrogel structure sandwiched between the polymer film layers. An ultrasound resonator cavity having a resonance frequency is defined between the top and bottom polymer layers, and the smart hydrogel structure is configured to provide a change in height to the ultrasound resonator cavity due to volumetric expansion or contraction of the smart hydrogel structure, in response to interaction of the smart hydrogel structure with one or more predefined analytes in an in vivo or other environment. Related methods of use for determining the presence or concentration of a given target analyte, as well as methods of fabricating such microresonator structures are also described.
    Type: Application
    Filed: July 2, 2021
    Publication date: November 4, 2021
    Inventors: Christopher F. Reiche, Navid Farhoudi, Florian Solzbacher, Jules J. Magda
  • Publication number: 20210267573
    Abstract: Systems and methods for measuring changes in smart hydrogel microresonator structures positioned in an in vivo or other environment, having an acoustic resonance frequency in an ultrasound range. The system includes a smart hydrogel microresonator structure positioned within the environment configured to exhibit a change in resonance frequency in response to interaction with one or more predefined analytes in the environment. The system includes an ultrasound transducer for querying the smart hydrogel microresonator structure at or near its resonance frequency. The system also includes a computer system configured to receive ultrasound data as provided by query of the smart hydrogel microresonator structure and to determine changes in resonance frequency, amplitude or intensity of the ultrasound query wave, or mean grayscale value (MGV) associated with the ultrasound data of the smart hydrogel microresonator structure due to the change in resonance frequency.
    Type: Application
    Filed: May 7, 2021
    Publication date: September 2, 2021
    Inventors: Christopher F. Reiche, Florian Solzbacher, Navid Farhoudi, Steven M. Blair, Jules J. Magda, Lars B. Laurentius, Prattay Deepta Kairy
  • Publication number: 20200326456
    Abstract: A weather-detecting device (100) can include a substrate (102) and a detection region (106) exposed to an environment within which the weather-detecting device (100) is situated when in use. An array (110) of heating elements (112) can be mounted at a first side of the substrate (102), with at least one surface of each heating element (112) in the array (110) being positioned within the detection region (106). A controller can be electrically coupled to the array (110) of heating elements (112), and the controller can individually address each heating element (112) in the array (110) to selectively pass electrical current through each heating element (112).
    Type: Application
    Filed: October 15, 2018
    Publication date: October 15, 2020
    Inventors: Timothy John Garrett, Florian Solzbacher, Konstantin Shkurko
  • Publication number: 20200114353
    Abstract: Microfluidics sensor devices having an array of smart polymer hydrogel features for resistive channel analyte sensing via hydrogel swelling and de-swelling, and methods of manufacturing and using the same. Inexpensive, rapid-responsive, point-of-use sensors for monitoring disease biomarkers or environmental contaminants in, for example, drinking water, employ smart polymer hydrogels as recognition elements that can be tailored to detect almost any target analyte. Fabrication involves mask-templated UV photopolymerization to produce an array of smart hydrogel pillars, with large surface area-to-volume ratios, inside sub-millimeter channels located on microfluidics devices. The pillars swell or shrink upon contact aqueous solutions containing a target analyte, thereby changing the resistance of the microfluidic channel to ionic current flow when a bias voltage is applied to the system. Hence resistance measurements can be used to transduce hydrogel swelling changes into electrical signals.
    Type: Application
    Filed: October 14, 2019
    Publication date: April 16, 2020
    Inventors: Hsuan-Yu Leu, Navid Farhoudi, Christopher F. Reiche, Julia Koerner, Swomitra Kumar Mohanty, Florian Solzbacher, Jules John Magda
  • Patent number: 10448895
    Abstract: A sensor sheath for a catheter. The sensor sheath includes a substrate having at least one sensor associated therewith; and an electronics unit in communication with at the at least one sensor, wherein the substrate is configured to attach to a catheter.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: October 22, 2019
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Prashant Tathireddy, Carlos Mastrangelo, Florian Solzbacher, Nassir Marrouche, Jules Magda
  • Publication number: 20190313977
    Abstract: A sensor sheath for a catheter. The sensor sheath includes a substrate having at least one sensor associated therewith and an electronics unit in communication with the at least one sensor, wherein the substrate is configured to attach to a catheter.
    Type: Application
    Filed: June 21, 2019
    Publication date: October 17, 2019
    Inventors: Prashant Tathireddy, Carlos Mastrangelo, Florian Solzbacher, Nassir Marrouche, Jules Magda
  • Publication number: 20190192113
    Abstract: Systems and methods for accurately measuring changes in biomarker sensitive hydrogel volume and shape due to exposure to various biomarkers include a system for identifying one or more dimensional changes in a biomarker sensitive hydrogel positioned within an in vivo environment. The system includes a biomarker sensitive hydrogel positioned within an in vivo environment and configured to dimensionally change in response to interaction with predefined biomarkers. The system additionally includes an ultrasound transducer for locating and identifying one or more characteristics of the biomarker sensitive hydrogel and a computer system in electrical communication with the ultrasound transducer. The computer system is configured to receive characteristics of the biomarker sensitive hydrogel from the ultrasound transducer and determine dimensional changes of the biomarker sensitive hydrogel based on the received characteristics.
    Type: Application
    Filed: September 1, 2017
    Publication date: June 27, 2019
    Inventors: Mahender nath Avula, Douglas A. Christensen, Navid Farhoudi, Stan Kanarowski, Julia Koerner, Jules John Magda, Rami Sami Marrouche, Christopher F. Reiche, Florian Solzbacher, Michael David Sorenson
  • Publication number: 20160015323
    Abstract: A sensor sheath for a catheter. The sensor sheath includes a substrate having at least one sensor associated therewith; and an electronics unit in communication with at the at least one sensor, wherein the substrate is configured to attach to a catheter.
    Type: Application
    Filed: March 11, 2014
    Publication date: January 21, 2016
    Inventors: Prashant Tathireddy, Carlos Mastrangelo, Florian Solzbacher, Nassir Marrouche, Jules Magda
  • Patent number: 8886279
    Abstract: A method of fabricating an array of micro electrodes enabled to have customizable lengths. A substantially criss-cross pattern of channels on a top surface of the work-piece substrate (10) is formed using electrical discharge machining to form a plurality of shaped columns (20) having tapered profiles. The shaped columns have a tapering profile which extends at least 50% of the length of the columns. The plurality of shaped columns is etched to sharpen the tapered tips into needle tips forming the array of microelectrodes.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: November 11, 2014
    Assignee: University of Utah Research Foundation
    Inventors: Prashant Tathireddy, Florian Solzbacher
  • Patent number: 8865288
    Abstract: A micro-needle array having tips disposed along a non-planar surface is formed by shaping the wafer surface into a non-planar surface to define the tips of the micro-needles. A plurality of trenches are cut into the wafer to form a plurality of columns having tops corresponding to the non-planar surface. The columns are rounded and sharpened by etching to form the micro-needles.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: October 21, 2014
    Assignee: University of Utah Research Foundation
    Inventors: Rajmohan Bhandari, Sandeep Negi, Florian Solzbacher, Richard A. Normann
  • Patent number: 8521303
    Abstract: An in-vivo implantable coil assembly includes a planar coil having at least one coil layer formed from conductive traces disposed in or on a polymer matrix. A ferrite platelet is bonded to a surface of the polymer matrix. Methods of making and using the in-vivo implantable coil assembly are also disclosed.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: August 27, 2013
    Assignee: University of Utah Reasearch Foundation
    Inventors: Florian Solzbacher, Reid R. Harrison, Richard A. Normann, Sohee Kim, Michael Töpper, Hans-Hermann Oppermann, Klaus Buschick, Matthias Klein
  • Publication number: 20130046148
    Abstract: A hybrid optical-electrical neural interface is disclosed and described. The neural interface can include an array (100) having a plurality of micro-optrodes (HO). The micro-optrodes (110) are capable of optical and optionally electrical stimulation and recording, allowing bidirectional, multi-modal communication with neural tissue. At least a portion of the plurality of micro-optrodes (110) are independently optically addressable and include an optical waveguide along each micro-optrode (HO). Combining optical stimulation with electrical recording can allow artifact-free recording from nearby electrodes and in some cases even the same electrode, which is difficult to achieve with combined electrical recording and stimulation. The optical waveguide is configured to direct light towards a distal end (125) of the micro-optrode, allowing focal stimulation and recording. Penetrating micro-optrodes (110) can allow access to deep tissue, while non-penetrating micro-optrodes can be used for extraneural stimulation.
    Type: Application
    Filed: November 9, 2010
    Publication date: February 21, 2013
    Inventors: Prashant Tathireddy, Loren Rieth, Gregory Arthur Clark, Richard A. Normann, Florian Solzbacher, Steven Blair
  • Patent number: 8310682
    Abstract: A testing and analysis system for a pressure-sensitive device (42) that includes a testing stage (10) comprising a platform having a groove situated on an upper surface, an endless support gasket located in the endless groove, a pressure port located on the upper surface and interior to the endless groove, and a means for securing a substrate above the upper surface. The substrate (40) supports a pressure-sensitive device (42) to form a pressure chamber between the substrate (40) and the upper surface. A pressure source (32) is operatively connected to the pressure port to modify a pressure inside the pressure chamber and deflect the pressure-sensitive device (42). A surface profile measurement apparatus (104) is included for measuring a surface profile of the deflected pressure-sensitive device (42).
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: November 13, 2012
    Assignee: University of Utah Research Foundation
    Inventors: Michael Orthner, Florian Solzbacher, Loren Rieth
  • Publication number: 20120138335
    Abstract: A method of fabricating an array of micro electrodes enabled to have customizable lengths. A substantially criss-cross pattern of channels on a top surface of the work-piece substrate (10) is formed using electrical discharge machining to form a plurality of shaped columns (20) having tapered profiles. The shaped columns have a tapering profile which extends at least 50% of the length of the columns. The plurality of shaped columns is etched to sharpen the tapered tips into needle tips forming the array of microelectrodes.
    Type: Application
    Filed: June 3, 2009
    Publication date: June 7, 2012
    Applicant: University of Utah Research Foundation
    Inventors: Prashant Tathireddy, Florian Solzbacher
  • Publication number: 20120132613
    Abstract: Methods for wafer-scale fabrication of needle arrays can include mechanically modifying a wafer to produce a plurality of vertically-extending columns. The columns are etched to round and reshape the columns into substantially uniformly shaped needles. Needle arrays having needle width non-uniformity of less than about 3% and length non-uniformity of less than about 2% can be produced.
    Type: Application
    Filed: May 27, 2011
    Publication date: May 31, 2012
    Inventors: Rajmohan Bhandari, Sandeep Negi, Florian Solzbacher, Richard A. Normann
  • Publication number: 20110260163
    Abstract: An improved piezoresistive-based sensor (78) can include a cavity (66) in a substantially solid substrate (68). A reactive agent can optionally be present in the cavity (66). A flexible machined membrane can form a wall of the cavity (66). The flexible machined membrane can include an array of channels (76) configured to permit selective passage of a target material into and out of the cavity. Additionally, the flexible machined membrane can include a piezoresistive features (74) associated with the membrane. The reactive agent included in the cavity (66) can be volumetrically responsive to the presence of the target material or fluid. These sensors can be configured as pressure sensors, chemical sensors, flow sensors, and the like.
    Type: Application
    Filed: March 13, 2009
    Publication date: October 27, 2011
    Inventors: Florian Solzbacher, Michael Orthner