Patents by Inventor Florian Uhle

Florian Uhle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnosis and risk stratification of fungal infections
    Patent number: 11592450
    Abstract: The invention relates to a method for the diagnosis and/or risk stratification of invasive fungal infections (IFI)/invasive fungal diseases (IFD) and in particular associated with sepsis or septic shock, wherein a determination of the marker proadrenomedullin (proADM) or a partial peptide or fragment thereof, in particular midregional proadrenomedullin (MR-proADM), or contained in a marker combination (panel, cluster), is carried out from a patient to be examined. Furthermore, the invention relates to a diagnostic assay and a kit for carrying out the method.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: February 28, 2023
    Assignee: B.R.A.H.M.S GMBH
    Inventors: Thorsten Brenner, Markus Alexander Weigand, Florian Uhle, Darius Cameron Wilson
  • Delta-like ligand 1 for diagnosing severe infections
    Patent number: 11181532
    Abstract: The invention refers to a method for in vitro diagnosis of a severe infection comprising determining delta-like ligand 1 protein or a nucleotide sequence coding for delta-like ligand 1 protein in a biological sample wherein an elevated level of expression of delta-like ligand 1 protein or a nucleotide sequence coding for delta-like ligand 1 protein is indicative of a severe infection; and the use of delta-like ligand 1 protein as a biomarker for in vitro diagnosis of a severe infection such as sepsis.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: November 23, 2021
    Assignee: UNIVERSITÄT HEIDELBERG
    Inventors: Dagmar Hildebrand, Klaus Heeg, Florian Uhle, Markus Weigand
  • DIAGNOSIS AND RISK STRATIFICATION OF FUNGAL INFECTIONS
    Publication number: 20200371113
    Abstract: The invention relates to a method for the diagnosis and/or risk stratification of invasive fungal infections (IFI)/invasive fungal diseases (IFD) and in particular associated with sepsis or septic shock, wherein a determination of the marker proadrenomedullin (proADM) or a partial peptide or fragment thereof, in particular midregional proadrenomedullin (MR-proADM), or contained in a marker combination (panel, cluster), is carried out from a patient to be examined. Furthermore, the invention relates to a diagnostic assay and a kit for carrying out the method.
    Type: Application
    Filed: August 6, 2018
    Publication date: November 26, 2020
    Applicants: B.R.A.H.M.S GMBH, UNIVERSITAT HEIDELBERG
    Inventors: Thorsten BRENNER, Markus Alexander WEIGAND, Florian UHLE, Darius Cameron WILSON
  • DELTA-LIKE LIGAND 1 FOR DIAGNOSING SEVERE INFECTIONS
    Publication number: 20200341007
    Abstract: The invention refers to a method for in vitro diagnosis of a severe infection comprising determining delta-like ligand 1 protein or a nucleotide sequence coding for delta-like ligand 1 protein in a biological sample wherein an elevated level of expression of delta-like ligand 1 protein or a nucleotide sequence coding for delta-like ligand 1 protein is indicative of a severe infection; and the use of delta-like ligand 1 protein as a biomarker for in vitro diagnosis of a severe infection such as sepsis.
    Type: Application
    Filed: October 25, 2018
    Publication date: October 29, 2020
    Inventors: Dagmar Hildebrand, Klaus Heeg, Florian Uhle, Markus Weigand