Patents by Inventor Florie BERTRAND

Florie BERTRAND has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and pharmaceutical compositions for enhancing CD8+ T cell-dependent immune responses in subjects suffering from cancer
    Patent number: 11078277
    Abstract: The present invention relates to methods and pharmaceutical compositions for enhancing CD8+ T cell-dependent immune responses in subjects suffering from cancer. In particular, the present invention relates to a method of enhancing the CD8+ T cell-dependent immune response in a subject suffering from cancer comprising administering to the subject a therapeutically effective amount of an agent capable of increasing intra-tumoral ceramide content.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: August 3, 2021
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE PAUL SABATIER TOULOUSE III, CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE
    Inventors: Thierry Levade, Bruno Segui, Florie Bertrand, Julia Rochotte, Anne Montfort, Nathalie Andrieu-Abadie, Celine Colacios Viatge, Nicolas Meyer
  • METHODS AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CANCER
    Publication number: 20210145977
    Abstract: The present invention relates to methods and pharmaceutical composition for the treatment of cancer. In particular, the present invention relates to a method for enhancing the potency of an immune checkpoint inhibitor administered to a subject as part of a treatment regimen for cancer, the method comprising: administering a pharmaceutically effective amount of a TNF? blocking agent to a subject in combination with the immune checkpoint inhibitor.
    Type: Application
    Filed: January 12, 2021
    Publication date: May 20, 2021
    Inventors: Thierry LEVADE, Bruno SEGUI, Nicolas MEYER, Céline COLACIOS VIATGÉ, Nathalie ANDRIEU-ABADIE, Florie BERTRAND
  • Methods and pharmaceutical composition for the treatment of cancer
    Patent number: 10918737
    Abstract: The present invention relates to methods and pharmaceutical composition for the treatment of cancer. In particular, the present invention relates to a method for enhancing the potency of an immune checkpoint inhibitor administered to a subject as part of a treatment regimen for cancer, the method comprising: administering a pharmaceutically effective amount of a TNF? blocking agent to a subject in combination with the immune checkpoint inhibitor.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: February 16, 2021
    Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Université Paul Sabatier Toulouse III, Centre Hospitalier Universitaire de Toulouse
    Inventors: Thierry Levade, Bruno Segui, Nicolas Meyer, Céline Colacios Viatgé, Nathalie Andrieu-Abadie, Florie Bertrand
  • METHODS AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CANCER
    Publication number: 20190038763
    Abstract: The present invention relates to methods and pharmaceutical composition for the treatment of cancer. In particular, the present invention relates to a method for enhancing the potency of an immune checkpoint inhibitor administered to a subject as part of a treatment regimen for cancer, the method comprising: administering a pharmaceutically effective amount of a TNF? blocking agent to a subject in combination with the immune checkpoint inhibitor.
    Type: Application
    Filed: January 27, 2017
    Publication date: February 7, 2019
    Inventors: Thierry LEVADE, Bruno SEGUI, Nicolas MEYER, Céline COLACIOS VIATGÉ, Nathalie ANDRIEU-ABADIE, Florie BERTRAND
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING CD8+ T CELL-DEPENDENT IMMUNE RESPONSES IN SUBJECTS SUFFERING FROM CANCER
    Publication number: 20190031756
    Abstract: The present invention relates to methods and pharmaceutical compositions for enhancing CD8+ T cell-dependent immune responses in subjects suffering from cancer. In particular, the present invention relates to a method of enhancing the CD8+ T cell-dependent immune response in a subject suffering from cancer comprising administering to the subject a therapeutically effective amount of an agent capable of increasing intra-tumoral ceramide content.
    Type: Application
    Filed: February 1, 2017
    Publication date: January 31, 2019
    Inventors: Thierry LEVADE, Bruno SEGUI, Florie BERTRAND, Julia ROCHOTTE, Anne MONTFORT, Nathalie ANDRIEU-ABADIE, Celine COLACIOS VIATGE, Nicolas MEYER
  • Method for treating melanoma
    Patent number: 10144772
    Abstract: The present invention relates to a TNF? blocking agent for use in the treatment and prevention of melanoma in a subject in whom melanoma cells express MHCI and in whom stroma cells exhibit TNF expression.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: December 4, 2018
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Centre Hospitalier Universitaire de Toulouse, Institut Claudius Regaud, Universite Paul Sabatier Toulouse III
    Inventors: Bruno Segui, Nathalie Andrieu-Abadie, Thierry Levade, Celine Colacios Viatge, Philippe Rochaix, Florie Bertrand, Herve Benoist, Julia Rochotte
  • NEW METHOD FOR TREATING MELANOMA
    Publication number: 20170174744
    Abstract: The present invention relates to a TNF? blocking agent for use in the treatment and prevention of melanoma in a subject in whom melanoma cells express MHCI and in whom stroma cells exhibit TNF expression.
    Type: Application
    Filed: May 12, 2015
    Publication date: June 22, 2017
    Inventors: Bruno SEGUI, Nathalie ANDRIEU-ABADIE, Thierry LEVADE, Celine COLACIOS VIATGE, Philippe ROCHAIX, Florie BERTRAND, Herve BENOIST, Julia ROCHOTTE