Patents by Inventor Forest M. White

Forest M. White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING CANCERS ASSOCIATED WITH CONSTITUTIVE EGFR SIGNALING
    Publication number: 20090042906
    Abstract: Aspects of the invention relate to methods and compositions for treating cancers associated with constitutive EGFR signaling. Methods include inhibiting one or more components of the c-Met and/or Axl signaling pathways. Aspects of the invention also relate to methods for determining whether a subject is a candidate for treatment with an inhibitor of a c-Met and/or Axl signaling component.
    Type: Application
    Filed: April 25, 2008
    Publication date: February 12, 2009
    Applicant: Massachusetts Institute of Technology
    Inventors: Hua Ming Paul Huang, Forest M. White
  • Systems and methods for the analysis of protein phosphorylation
    Patent number: 7026167
    Abstract: The present invention relates to a method of applying mass spectrometry to analyzing peptides or proteins, especially in the proteome setting. More particularly, the invention relates to a mass spectrometry-based method for detection of protein/peptide phosphorylation wherein the side chains of glutamic acid and/or aspartic acid residues of said peptides or proteins are chemically modified as to improve the selectivity/efficiency of identification of the phosphorylated protein/peptide.
    Type: Grant
    Filed: December 26, 2002
    Date of Patent: April 11, 2006
    Assignee: University of Virginia Patent Foundation
    Inventors: Donald F. Hunt, Forest M. White, Scott Ficarro
  • Phosphorylated proteins and uses related thereto
    Publication number: 20030232014
    Abstract: Methods and systems of applying mass spectrometry to the analysis of peptides and amino acids, especially in the proteome setting. More particularly, the invention relates to a mass spectrometry-based method for detection of amino acid modifications, such as phosphorylation.
    Type: Application
    Filed: March 3, 2003
    Publication date: December 18, 2003
    Applicants: MDS Proteomics Inc., University of Virginia
    Inventors: Daniel J. Burke, Mark M. Ross, P. Todd Stukenberg, Forest M. White
  • Systems and methods for the analysis of protein phosphorylation
    Publication number: 20030224967
    Abstract: Methods and systems of applying mass spectrometry to the analysis of peptides and amino acids, especially in the proteome setting. More particularly, the invention relates to a mass spectrometry-based method for detection of amino acid phosphorylation.
    Type: Application
    Filed: December 26, 2002
    Publication date: December 4, 2003
    Inventors: Donald F. Hunt, Forest M. White, Scott Ficarro
  • Automated systems and methods for analysis of protein post-translational modification
    Publication number: 20030153007
    Abstract: Methods and systems of applying mass spectrometry to the analysis of peptides and amino acids, especially in the proteome setting. More particularly, the invention relates to a mass spectrometry-based method for detection of amino acid modifications, such as phosphorylation.
    Type: Application
    Filed: December 26, 2002
    Publication date: August 14, 2003
    Inventors: Jian Chen, Joseph Michel Daniel Figeys, Brett Larsen, Forest M. White
  • MHC class I associated peptides for prevention and treatment of tuberculosis
    Publication number: 20020192229
    Abstract: The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of tuberculosis, and discloses peptides, polypeptides, and polynucleotides that can be used to stimulate a CTL response against tuberculosis. The peptide and/or proteins of the invention may be used as a therapeutic drug to stimulate the immune system to recognize and eliminate M. tuberculosis in infected cells or as a vaccine for the prevention of disease. Antibodies that react with the immunogens of the invention, as well as methods of using these antibodies for prevention and treatment of disease, are also disclosed.
    Type: Application
    Filed: December 13, 2001
    Publication date: December 19, 2002
    Inventors: David Flyer, Mark M. Ross, Donald F. Hunt, Forest M. White, Victor H. Engelhard, Ramila Philip