Abstract: The present invention relates to novel "pseudo" nonapeptide and decapeptide derivatives of LHRH. More particularly the present invention relates to derivatives of LHRH wherein the nitrogen atom of at least one of the amide bonds has been alkylated.

Abstract: Described are compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 independently of one another denote hydrogen or loweralkyl, X is hydroxy or amino, and Y is hydrogen, loweralkyl, loweralkoxy, benzyl or ##STR2## wherein W and Z independently of one another denote hydrogen, halo, loweralkyl, loweralkoxy, trifluoromethyl, acetamido, cyano, diloweralkylamino, phenoxy and loweralkylmercapto, and pharmaceutically acceptable salts thereof.The compounds are effective as anti-inflammatory agents.

Abstract: Described are oxazolyl (or thiazolyl) hydrazinoalkyl nitrile compounds of the formula ##STR1## wherein R is hydrogen or loweralkyl, R.sub.1 and R.sub.2 independently of one another denote hydrogen, loweralkyl, or phenyl or naphthyl substituted with halo, loweralkyl or loweralkoxy, X is oxygen or sulfur, n and m are each an integer from 0 to 3 inclusive, or pharmaceutically acceptable salts thereof. The compounds are useful as anti-inflammatory agents.

Abstract: Described are compounds of the formula ##STR1## wherein R is hydrogen or loweralkyl, X, Y and W independently of one another denote hydrogen, halogen, loweralkyl, nitro, amino, amido, loweralkoxy, hydroxy, nitrile, methylsulfone, methylsulfoxide, methylmercapto, or trifluoromethyl; Z is oxygen, sulfur or --CH.sub.2 ; n and m are each an integer from 0 to 6 inclusive, or pharmaceutically acceptable salts thereof.The compounds are effective as anti-inflammatory agents.

Abstract: Described are compounds of the formula ##STR1## wherein R.sub.2 -R.sub.8 independently of one another denote hydrogen, loweralkyl, phenyl, alkoxy, halo, hydroxy, nitro, trifluoromethyl, ##STR2## with the proviso that at least one but no more than one of the substituents R.sub.2 -R.sub.8 is ##STR3## and with the further provisos that at least four of the substituents R.sub.2 -R.sub.8 are hydrogen and R.sub.2 cannot be ##STR4## when R.sub.3 -R.sub.8 are hydrogen, and pharmaceutically acceptable salts thereof.The compounds are effective as antiinflammatory and antiasthma agents.

Abstract: A method for treating an inflammatory condition in a mammalian patient by administering an effective amount of a 1-aralkyl-3-amino-2-pyrazoline compound having the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof, wherein: m and n are integers ranging from 0 to 6,R.sub.1, R.sub.2, R.sub.3, R.sub.4, and R.sub.5, which can be the same or different, are hydrogen or lower alkyl,X.sub.1, X.sub.2, X.sub.3, X.sub.4, and X.sub.5, which can be the same or different, are hydrogen, halogen, alkyl, cycloalkyl, alkoxy, alkanoyloxy, phenyl, phenoxy, benzyloxy, haloalkyl, mercaptoalkyl, amino, alkylamine, hydroxyl, nitro, and nitrile,each of X.sub.1 -X.sub.5, when they contain carbon, having not more than 6 carbon atoms.The compounds used in the method have unexpectedly low toxicity.

Abstract: It has been found that certain 4-substituted 2-hydroxylaminomethyl phenols or their nontoxic pharmaceutically acceptable acid addition salts are excellent diuretic, saluretic and anti-inflammatory agents.

Abstract: It has been found that bis(2-benzylaminoethyl)-disulfides with the phenyl rings carrying various simple substituents, are highly effective anti-inflammatories and inhibit chemotaxis of human neutrophils.

Abstract: Novel cephalosporin compounds of the following formula are useful as antibiotic agents: ##STR1##

Abstract: Novel cephalosporin derivatives of the following formula are useful as antibacterial agents: ##STR1##

Abstract: Novel pyridylthiomethyl substituted cephalosporin compounds having the formula ##STR1## wherein R is 2-pyridyl, 3-pyridyl or 4-pyridyl.

Abstract: Novel cephalosporin compounds of the following formula are useful as antibiotic agents: ##STR1##

Abstract: Novel cephalosporin derivatives of the following formula are useful as antibacterial agents: ##STR1##

Abstract: Novel pyridylthiomethyl substituted cephalosporin compounds having the formula ##STR1## wherein R is 2-pyridyl, 3-pyridyl or 4-pyridyl.

Abstract: Novel cephalosporin antibiotic derivatives.

Abstract: Novel cephalosporin antibiotic derivatives.

Abstract: Novel cephalosporin antibiotic derivatives.

Abstract: Novel cephalosporin antibiotic derivatives.

Abstract: Novel cephalosporin antibiotic derivatives.

Abstract: Novel cephalosporin antibiotic derivatives.