Patents by Inventor Fozan O. El-Nounou
Fozan O. El-Nounou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9504491Abstract: A method is provided including introducing a delivery device through a vessel wall to a treatment site within one of a peri-adventitial space or a pericardium adjacent a coronary blood vessel and delivering a treatment agent through the delivery device. The treatment agent is delivered through the delivery device according to conditions that hydraulically dissect tissue planes within the peri-adventitial space. A kit is provided including a delivery device having a needle to be advanced through one of an epicardium of a heart and a wall of a coronary blood vessel into a peri-adventitial space and a treatment agent comprising particles having an average diameter on the order of 15 microns or more to be delivered through the delivery device into the peri-adventitial space.Type: GrantFiled: November 7, 2007Date of Patent: November 29, 2016Assignee: Abbott Cardiovascular Systems Inc.Inventors: Peter L. Callas, Eric J. Willis, Fozan O. El-Nounou, Florian N. Ludwig, William E. Webler, Paul M. Consigny
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Patent number: 9144509Abstract: Devices for delivering drugs or other treatment agents locally to the vasculature of a mammal are disclosed. These devices have several related structures and are designed to deliver the drugs to facilitate rapid mixing with the blood flowing past the devices.Type: GrantFiled: October 12, 2010Date of Patent: September 29, 2015Assignee: Abbott Cardiovascular Systems Inc.Inventors: Paul M. Consigny, David C. Gale, Florian Ludwig, Randolpf von Oepen, Fozan O. El-Nounou, Pamela A. Kramer-Brown, Travis R. Yribarren, William E. Webler, Jr.
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Patent number: 9108028Abstract: A method is described including introducing a delivery device to a point within a renal artery or a renal segmental artery and delivering a treatment agent from the delivery device according to conditions that create a turbulent blood flow and wherein the treatment agent is capable of inhibiting a biological process contributing to nephropathy. In other embodiments, an apparatus and kit are described including a delivery device for insertion to a point within a renal artery or renal segmental artery and delivery of a treatment agent capable of inhibiting a biological process contributing to nephropathy.Type: GrantFiled: April 13, 2012Date of Patent: August 18, 2015Assignee: Abbott Cardivascular Systems Inc.Inventors: Paul M. Consigny, Fozan O. El-Nounou, David C. Gale, Pamela A. Kramer-Brown
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Patent number: 8858611Abstract: Sterilization methods for implantable prostheses are described where a polymeric stent may be sterilized, e.g., via ETO sterilization, at a temperature below a glass transition temperature of the stent. A separate delivery catheter may be sterilized separately and the stent and delivery catheter may then be combined in an aseptic or semi-aseptic environment and sterilized as an assembled system such that the requirements for sterilizing the system are relatively lower. Additionally and/or alternatively, valve and filter assemblies may be used with an optional mandrel assembly for maintaining sterility of the internal components of a catheter system.Type: GrantFiled: July 3, 2013Date of Patent: October 14, 2014Assignee: Amaranth Medical, PteInventors: Kamal Ramzipoor, Chang Y. Lee, Fozan O. El-Nounou
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Patent number: 8641666Abstract: Catheters with laminar flow bioactive agent delivery properties and methods of using for treating or preventing vascular disease are disclosed.Type: GrantFiled: May 16, 2007Date of Patent: February 4, 2014Assignee: Abbott Cardiovascular Systems Inc.Inventors: Fozan O. El-Nounou, Florian N. Ludwig, Syed F. A. Hossainy, Paul Consigny
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Publication number: 20130294979Abstract: Sterilization methods for implantable prostheses are described where a polymeric stent may be sterilized, e.g., via ETO sterilization, at a temperature below a glass transition temperature of the stent. A separate delivery catheter may be sterilized separately and the stent and delivery catheter may then be combined in an aseptic or semi-aseptic environment and sterilized as an assembled system such that the requirements for sterilizing the system are relatively lower. Additionally and/or alternatively, valve and filter assemblies may be used with an optional mandrel assembly for maintaining sterility of the internal components of a catheter system.Type: ApplicationFiled: July 3, 2013Publication date: November 7, 2013Inventors: Kamal RAMZIPOOR, Chang Y. LEE, Fozan O. EL-NOUNOU
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Patent number: 8574493Abstract: Sterilization methods for implantable prostheses are described, where a polymeric stent may be sterilized, e.g., via ETO sterilization, at a temperature below a glass transition temperature of the stent. A separate delivery catheter may be sterilized separately and the stent and delivery catheter may then be combined in an aseptic, or semi-aseptic environment and sterilized as an assembled system such that the requirements for sterilizing the system are relatively lower. Additionally and/or alternatively, valve and filter assemblies may be used with an optional mandrel assembly for maintaining sterility of the internal components of a catheter system.Type: GrantFiled: November 7, 2012Date of Patent: November 5, 2013Assignee: Amaranth Medical Pte.Inventors: Kamal Ramzipoor, Chang Y. Lee, Fozan O. El-Nounou
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Patent number: 8496615Abstract: A method is described including introducing a delivery device to a point within a renal artery or a renal segmental artery and delivering a treatment agent from the delivery device according to conditions that create a turbulent blood flow and wherein the treatment agent is capable of inhibiting a biological process contributing to nephropathy. In other embodiments, an apparatus and kit are described including a delivery device for insertion to a point within a renal artery or renal segmental artery and delivery of a treatment agent capable of inhibiting a biological process contributing to nephropathy.Type: GrantFiled: April 13, 2012Date of Patent: July 30, 2013Assignee: Abbott Cardiovascular Systems, Inc.Inventors: Paul M. Consigny, Fozan O. El-Nounou, David C. Gale, Pamela A. Kramer-Brown
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Patent number: 8309023Abstract: Sterilization methods for implantable prostheses are described where a polymeric stent may be sterilized, e.g., via ETO sterilization, at a temperature below a glass transition temperature of the stent. A separate delivery catheter may be sterilized separately and the stent and delivery catheter may then be combined in an aseptic or semi-aseptic environment and sterilized as an assembled system such that the requirements for sterilizing the system are relatively lower. Additionally and/or alternatively, valve and filter assemblies may be used with an optional mandrel assembly for maintaining sterility of the internal components of a catheter system.Type: GrantFiled: December 29, 2009Date of Patent: November 13, 2012Assignee: Amaranth Medical Pte.Inventors: Kamal Ramzipoor, Chang Y. Lee, Fozan O. El-Nounou
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Publication number: 20120203174Abstract: A method is described including introducing a delivery device to a point within a renal artery or a renal segmental artery and delivering a treatment agent from the delivery device according to conditions that create a turbulent blood flow and wherein the treatment agent is capable of inhibiting a biological process contributing to nephropathy. In other embodiments, an apparatus and kit are described including a delivery device for insertion to a point within a renal artery or renal segmental artery and delivery of a treatment agent capable of inhibiting a biological process contributing to nephropathy.Type: ApplicationFiled: April 13, 2012Publication date: August 9, 2012Applicant: Abbot Cardiovascular Systems Inc.Inventors: Paul M. Consigny, Fozan O. El-Nounou, David C. Gale, Pamela A. Kramer-Brown
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Publication number: 20120203202Abstract: A method is described including introducing a delivery device to a point within a renal artery or a renal segmental artery and delivering a treatment agent from the delivery device according to conditions that create a turbulent blood flow and wherein the treatment agent is capable of inhibiting a biological process contributing to nephropathy. In other embodiments, an apparatus and kit are described including a delivery device for insertion to a point within a renal artery or renal segmental artery and delivery of a treatment agent capable of inhibiting a biological process contributing to nephropathy.Type: ApplicationFiled: April 13, 2012Publication date: August 9, 2012Applicant: Abbott Cardiovascular Systems Inc.Inventors: Paul M. Consigny, Fozan O. El-Nounou, David C. Gale, Pamela A. Kramer-Brown
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Patent number: 8216209Abstract: A method is described including introducing a delivery device to a point within a renal artery or a renal segmental artery and delivering a treatment agent from the delivery device according to conditions that create a turbulent blood flow and wherein the treatment agent is capable of inhibiting a biological process contributing to nephropathy. In other embodiments, an apparatus and kit are described including a delivery device for insertion to a point within a renal artery or renal segmental artery and delivery of a treatment agent capable of inhibiting a biological process contributing to nephropathy.Type: GrantFiled: May 31, 2007Date of Patent: July 10, 2012Assignee: Abbott Cardiovascular Systems Inc.Inventors: Paul M. Consigny, Fozan O. El-Nounou, David C. Gale, Pamela A. Kramer-Brown
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Publication number: 20110190698Abstract: Devices for delivering drugs or other treatment agents locally to the vasculature of a mammal are disclosed. These devices have several related structures and are designed to deliver the drugs to facilitate rapid mixing with the blood flowing past the devices.Type: ApplicationFiled: October 12, 2010Publication date: August 4, 2011Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.Inventors: Paul M. Consigny, David C. Gale, Florian Ludwig, Randolph von Oepen, Fozan O. El-Nounou, Pamela A. Kramer-Brown, Travis R. Yribarren, JR., William E. Webler, JR.
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Publication number: 20110046709Abstract: Various methods for implanting a stent into an ostium or a proximal portion of a body vessel utilizing a guide catheter, rather than a convention balloon angioplasty balloon catheter, as the primary delivery device are disclosed. The guide catheter can be used as the primary stent delivery catheter for the ostium region of the body vessel and can be anchored to the vessel to allow secondary treatment devices to be advanced to distal locations in the body vessel.Type: ApplicationFiled: August 18, 2009Publication date: February 24, 2011Applicant: ABBOTT CARDIOVASCULAR SYSTEMS, INC.Inventors: Lorcan J. Coffey, Diem U. Ta, Randolf von Oepen, Fozan O. El-Nounou, Laura M. Kalvass
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Publication number: 20100185270Abstract: Sterilization methods for implantable prostheses are described where a polymeric stent may be sterilized, e.g., via ETO sterilization, at a temperature below a glass transition temperature of the stent. A separate delivery catheter may be sterilized separately and the stent and delivery catheter may then be combined in an aseptic or semi-aseptic environment and sterilized as an assembled system such that the requirements for sterilizing the system are relatively lower. Additionally and/or alternatively, valve and filter assemblies may be used with an optional mandrel assembly for maintaining sterility of the internal components of a catheter system.Type: ApplicationFiled: December 29, 2009Publication date: July 22, 2010Applicant: AMARANTH MEDICAL PTE.Inventors: Kamal Ramzipoor, Chang Yeul Lee, Fozan O. El-Nounou
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Publication number: 20090118700Abstract: A method is provided including introducing a delivery device through a vessel wall to a treatment site within one of a peri-adventitial space or a pericardium adjacent a coronary blood vessel and delivering a treatment agent through the delivery device. The treatment agent is delivered through the delivery device according to conditions that hydraulically dissect tissue planes within the peri-adventitial space. A kit is provided including a delivery device having a needle to be advanced through one of an epicardium of a heart and a wall of a coronary blood vessel into a peri-adventitial space and a treatment agent comprising particles having an average diameter on the order of 15 microns or more to be delivered through the delivery device into the peri-adventitial space.Type: ApplicationFiled: November 7, 2007Publication date: May 7, 2009Inventors: Peter L. Callas, Eric J. Willis, Fozan O. El-Nounou, Florian N. Ludwig, William E. Webler, Paul M. Consigny
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Publication number: 20080300573Abstract: A method is described including introducing a delivery device to a point within a renal artery or a renal segmental artery and delivering a treatment agent from the delivery device according to conditions that create a turbulent blood flow and wherein the treatment agent is capable of inhibiting a biological process contributing to nephropathy. In other embodiments, an apparatus and kit are described including a delivery device for insertion to a point within a renal artery or renal segmental artery and delivery of a treatment agent capable of inhibiting a biological process contributing to nephropathy.Type: ApplicationFiled: May 31, 2007Publication date: December 4, 2008Inventors: Paul M. Consigny, Fozan O. El-Nounou, David C. Gale, Pamela A. Kramer-Brown
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Publication number: 20080287911Abstract: Catheters with laminar flow bioactive agent delivery properties and methods of using for treating or preventing vascular disease are disclosed.Type: ApplicationFiled: May 16, 2007Publication date: November 20, 2008Applicant: Abbott Cardiovascular Systems Inc.Inventors: Fozan O. El-Nounou, Florian N. Ludwig, Syed F.A. Hossainy, Paul Consigny
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Patent number: 5397310Abstract: A catheter introducer sheath assembly, for introduction into a body passage of a catheter containing a filter comprises a flexible introducer sheath joined to the distal end of a closure device forming a through-passage with a diameter sufficient to pass the catheter therethrough. The closure device has a resilient member in the through-passage and two rotatable body portions, one stationary with respect to the resilient member, and the other rotatable about the axis of the resilient member with an internal cam circumferentially spaced around the axis. A compression member positioned radially in an extending aperture makes contact with both the resilient member and the cam surface to vary the through-passage allowing the operator to manually control the passage of the device. The sheath assembly receives a cathetory guidewire that slides through and extends beyond the closure device and the sheath.Type: GrantFiled: March 1, 1993Date of Patent: March 14, 1995Assignee: Boston Scientific CorporationInventors: Michael S. H. Chu, Yem Chin, Fozan O. El-Nounou, James B. Daigle, Andrew H. Cragg
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Patent number: 5242462Abstract: A filter device positionable within a blood vessel for trapping blood clots in that vessel, the filter device comprising a head with a plurality of divergent legs each secured at its proximal end, to the head, each leg having a hook arranged at its distal end.Each leg has a radially outwardly directed radius of curvature to create a conical configuration to the filter assembly, while distributing the stress concentration along the length of the bend, so that the elastic limit of the material, stainless steel in this embodiment, is not exceeded, and which permits compact delivery of the filter, and adequate radially directed force to permit slight hook penetration of a vessel wall.Type: GrantFiled: October 17, 1991Date of Patent: September 7, 1993Assignee: Boston Scientific Corp.Inventors: Fozan O. El-Nounou, Michael A. Savin, Ronald A. Sahatjian, Michael Weinreich, Thomas F. Kordis