Patents by Inventor Frédéric Buffiere
Frédéric Buffiere has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200363434Abstract: Blood typing systems and methods are provided. In one embodiment, the method may be achieved by applying a sample to a surface of a substrate having one or more binding agents immobilized thereon, wherein the one or more binding agents are capable of binding to one or more substances in the sample; substantially removing unbound material from at least a portion of the substrate having immobilized binding agent; and detecting substances bound to the one or more binding agents immobilized on the substrate; wherein the applying the sample to the surface of the substrate step is concurrent with the removing unbound material from at least a portion of the substrate step. Systems and other methods are also described and illustrated.Type: ApplicationFiled: August 3, 2020Publication date: November 19, 2020Inventors: FREDERIC BUFFIERE, SYLVIE VILLARD-SAUSSINE, ELIANE RIVALIN, LAURENT GUILLON, JOHANN GUEGAN
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Patent number: 10732189Abstract: Blood typing systems and methods are provided. In one embodiment, the method may be achieved by applying a sample to a surface of a substrate having one or more binding agents immobilized thereon, wherein the one or more binding agents are capable of binding to one or more substances in the sample; substantially removing unbound material from at least a portion of the substrate having immobilized binding agent; and detecting substances bound to the one or more binding agents immobilized on the substrate; wherein the applying the sample to the surface of the substrate step is concurrent with the removing unbound material from at least a portion of the substrate step. Systems and other methods are also described and illustrated.Type: GrantFiled: January 14, 2016Date of Patent: August 4, 2020Assignee: BIO-RAD EUROPE GMBHInventors: Frederic Buffiere, Sylvie Villard-Saussine, Eliane Rivalin, Laurent Guillon, Johann Guegan
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Patent number: 10509028Abstract: The present disclosure relates to a device for detecting an analyte in a sample, and especially for detecting antigen/antibody reactions, wherein said device comprises a layer composed of a low-density immiscible compound. The disclosure also relates to a method for detecting an analyte in a sample and especially for detecting antigen/antibody reactions in a device comprising a layer composed of a low-density immiscible compound. The disclosure further relates to the uses of such low-density immiscible compound.Type: GrantFiled: May 18, 2016Date of Patent: December 17, 2019Assignee: BIO-RAD EUROPE GMBHInventors: Julien Agusti, Stephane Bombard, Frederic Buffiere
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Patent number: 10416180Abstract: The invention relates to a station for uncovering a receptacle comprising a body in which a plurality of adjacent holes, initially sealed by a cover, are formed. The station comprises at least one cutting member for making at least one cut in the cover between two adjacent holes, so as to form at least one cover portion closing off at least one of the holes of the receptacle, i.e., the selected hole; and at least one heating gripping device which is arranged so as to heat and remove said cover portion, thereby opening the selected hole.Type: GrantFiled: April 18, 2017Date of Patent: September 17, 2019Assignee: BIO-RAD EUROPE GMBHInventors: Sébastien Bernay, Jean-Michel Brisebrat, Frédéric Buffiere
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Publication number: 20180128818Abstract: The present disclosure relates to a device for detecting an analyte in a sample, and especially for detecting antigen/antibody reactions, wherein said device comprises a layer composed of a low-density immiscible compound. The disclosure also relates to a method for detecting an analyte in a sample and especially for detecting antigen/antibody reactions in a device comprising a layer composed of a low-density immiscible compound. The disclosure further relates to the uses of such low-density immiscible compound.Type: ApplicationFiled: May 18, 2016Publication date: May 10, 2018Inventors: JULIEN AGUSTI, STEPHANE BOMBARD, FREDERIC BUFFIERE
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Publication number: 20170370951Abstract: Blood typing systems and methods are provided. In one embodiment, the method may be achieved by applying a sample to a surface of a substrate having one or more binding agents immobilized thereon, wherein the one or more binding agents are capable of binding to one or more substances in the sample; substantially removing unbound material from at least a portion of the substrate having immobilized binding agent; and detecting substances bound to the one or more binding agents immobilized on the substrate; wherein the applying the sample to the surface of the substrate step is concurrent with the removing unbound material from at least a portion of the substrate step. Systems and other methods are also described and illustrated.Type: ApplicationFiled: January 14, 2016Publication date: December 28, 2017Inventors: FREDERIC BUFFIERE, SYLVIE VILLARD-SAUSSINE, ELIANE RIVALIN, LAURENT GUILLON, JOHANN GUEGAN
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Publication number: 20170219618Abstract: The invention relates to a station for uncovering a receptacle comprising a body in which a plurality of adjacent holes, initially sealed by a cover, are formed. The station comprises at least one cutting member for making at least one cut in the cover between two adjacent holes, so as to form at least one cover portion closing off at least one of the holes of the receptacle, i.e., the selected hole; and at least one heating gripping device which is arranged so as to heat and remove said cover portion, thereby opening the selected hole.Type: ApplicationFiled: April 18, 2017Publication date: August 3, 2017Applicants: BIO-RAD INNOVATIONS, DiaMed GmbHInventors: Sébastien BERNAY, Jean-Michel BRISEBRAT, Frédéric BUFFIERE
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Patent number: 9658141Abstract: The invention relates to a station for uncovering a receptacle comprising a body in which a plurality of adjacent holes, initially sealed by a cover, are formed. The station comprises at least one cutting member for making at least one cut in the cover between two adjacent holes, so as to form at least one cover portion closing off at least one of the holes of the receptacle, i.e., the selected hole; and at least one heating gripping device which is arranged so as to heat and remove said cover portion, thereby opening the selected hole.Type: GrantFiled: March 9, 2012Date of Patent: May 23, 2017Assignees: Bio-Rad Innovations, DiaMed GmbHInventors: Sébastien Bernay, Jean-Michel Brisebrat, Frédéric Buffiere
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Patent number: 9410974Abstract: A device for filling at least one receptacle (12) of gel card type initially sealed by a cap. The filling device comprises a piercing member (110) for perforating the cap, an ionization ramp (122) for eliminating the electrostatic charges capable of being borne by the receptacle, and filling means (130) one or more pipettes (132) for filling the receptacle after perforation of the cap and elimination of the electrostatic charges.Type: GrantFiled: September 22, 2015Date of Patent: August 9, 2016Assignee: BIO-RAD INNOVATIONSInventors: Frédéric Buffiere, Serge Petit, Jean-Michel Brisebrat
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Patent number: 9314789Abstract: Receptacle of gel card type comprising a body, formed in which are several adjacent wells, initially sealed by a cover having a length and a width. The cover has at least one precut between two adjacent wells so as to form at least one cover portion sealing at least one of the wells of the receptacle.Type: GrantFiled: March 9, 2012Date of Patent: April 19, 2016Assignees: DIAMED GMBH, BIO-RAD INNOVATIONSInventors: Sébastien Bernay, Jean-Michel Brisebrat, Frédéric Buffiere
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Publication number: 20160011226Abstract: The invention relates to a device for filling at least one receptacle (12) of gel card type initially sealed by a cap. The invention is characterized by the fact that the filling device comprises a piercing member (110) for perforating the cap, means (120) for eliminating the electrostatic charges capable of being borne by the receptacle, and filling means (130) for filling the receptacle after perforation of the cap and elimination of the electrostatic charges.Type: ApplicationFiled: September 22, 2015Publication date: January 14, 2016Inventors: Frédéric BUFFIERE, Serge PETIT, Jean-Michel BRISEBRAT
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Patent number: 9146249Abstract: The invention relates to a device for filling at least one receptacle (12) of gel card type initially sealed by a cap. The invention is characterized by the fact that the filling device comprises a piercing member (110) for perforating the cap, means (120) for eliminating the electrostatic charges capable of being borne by the receptacle, and filling means (130) for filling the receptacle after perforation of the cap and elimination of the electrostatic charges.Type: GrantFiled: March 31, 2010Date of Patent: September 29, 2015Assignee: BIO-RAD INNOVATIONSInventors: Frédéric Buffiere, Serge Petit, Jean-Michel Brisebrat
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Publication number: 20140124510Abstract: Receptacle of gel card type comprising a body, formed in which are several adjacent wells, initially sealed by a cover having a length and a width. The cover has at least one precut between two adjacent wells so as to form at least one cover portion sealing at least one of the wells of the receptacle.Type: ApplicationFiled: March 9, 2012Publication date: May 8, 2014Applicant: Bio-Rad InnovationsInventors: Sébastien Bernay, Jean-Michel Brisebrat, Frédéric Buffiere
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Publication number: 20140093972Abstract: The invention relates to a station for uncovering a receptacle comprising a body in which a plurality of adjacent holes, initially sealed by a cover, are formed. The station comprises at least one cutting member for making at least one cut in the cover between two adjacent holes, so as to form at least one cover portion closing off at least one of the holes of the receptacle, i.e., the selected hole; and at least one heating gripping device which is arranged so as to heat and remove said cover portion, thereby opening the selected hole.Type: ApplicationFiled: March 9, 2012Publication date: April 3, 2014Applicants: NOVILOIRE, BIO-RAD INNOVATIONSInventors: Sébastien Bernay, Jean-Michel Brisebrat, Frédéric Buffiere
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Patent number: 8580530Abstract: The invention relates to a method for detecting a plurality of antigenic molecules carried by erythrocytes and/or a plurality of anti-erythrocyte antibodies of an individual, comprising bringing a sample into contact with distinguishable beads, on which are attached a) antibodies specific for said antigens, or b) erythrocytes, erythrocyte membrane fragments or blood group antigens.Type: GrantFiled: June 6, 2008Date of Patent: November 12, 2013Assignee: Bio-Rad InnovationsInventors: Frederic Buffiere, Yves Raisin, Eliane Rivalin, Amparo Sanjuan
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Patent number: 8580531Abstract: The invention relates to a method for detecting a plurality of antigenic molecules carried by erythrocytes and/or a plurality of anti-erythrocyte antibodies, said antigenic molecules carried by the erythrocytes consisting of antigenic molecules carried not only by the erythrocytes, but also by at least one other cell population, other than the blood group antigen molecules, said method comprising bringing a sample into contact with distinguishable beads, on which are attached a) antibodies specific for said antigens, or b) erythrocytes or erythrocyte membrane fragment.Type: GrantFiled: June 6, 2008Date of Patent: November 12, 2013Assignee: Bio-Rad InnovationsInventors: Frederic Buffiere, Yves Raisin, Eliane Rivalin, Amparo Sanjuan
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Publication number: 20120051975Abstract: The invention relates to a device for filling at least one receptacle (12) of gel card type initially sealed by a cap. The invention is characterized by the fact that the filling device comprises a piercing member (110) for perforating the cap, means (120) for eliminating the electrostatic charges capable of being borne by the receptacle, and filling means (130) for filling the receptacle after perforation of the cap and elimination of the electrostatic charges.Type: ApplicationFiled: March 31, 2010Publication date: March 1, 2012Applicant: BIO-RAD INNOVATIONSInventors: Frederic Buffiere, Serge Petit, Jean-Michel Brisebrat
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Publication number: 20110256552Abstract: The present invention relates to a method of preparation of a solid substrate capable of immobilizing at least one cell and/or at least one part of a cell, said method comprising a step consisting of fixing, to said solid substrate, a fusogenic compound capable of being inserted in cell membranes. The present invention also relates to a method for immobilizing at least one cell and/or at least one part of a cell using the solid substrate thus prepared, said solid substrate and its uses in the area of biomedical diagnostics or health monitoring of biological fluids or intended for human or animal use.Type: ApplicationFiled: April 11, 2008Publication date: October 20, 2011Inventors: Gérard Deleris, Sandra Rubio Albenque, Bernard Bennetau, Bernard Desbat, Frédéric Buffiere, Jean-Luc Chagnaud
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Publication number: 20100184101Abstract: The invention relates to a method for detecting a plurality of antigenic molecules carried by erythrocytes and/or a plurality of anti-erythrocyte antibodies, said antigenic molecules carried by the erythrocytes consisting of antigenic molecules carried not only by the erythrocytes, but also by at least one other cell population, other than the blood group antigen molecules, said method comprising bringing a sample into contact with distinguishable beads, on which are attached a) antibodies specific for said antigens, or b) erythrocytes or erythrocyte membrane fragment.Type: ApplicationFiled: June 6, 2008Publication date: July 22, 2010Applicant: Bio-Rad PasteurInventors: Frederic Buffiere, Yves Raisin, Eliane Rivalin, Amparo Sanjuan
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Publication number: 20100178656Abstract: The invention relates to a method for detecting a plurality of antigenic molecules carried by erythrocytes and/or a plurality of anti-erythrocyte antibodies of an individual, comprising bringing a sample into contact with distinguishable beads, on which are attached a) antibodies specific for said antigens, or b) erythrocytes, erythrocyte membrane fragments or blood group antigens.Type: ApplicationFiled: June 6, 2008Publication date: July 15, 2010Applicant: BIO-RAD PASTEURInventors: Frederic Buffiere, Yves Raisin, Eliane Rivalin, Amparo Sanjuan