Patents by Inventor Frédéric Buron

Frédéric Buron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ion channel inhibitor compounds for cancer treatment
    Patent number: 11932638
    Abstract: The present invention concerns a compound of following general formula (I): where: either R is an R1 group and R? is an -A1-Cy1 group, or R is an -A1-Cy1 group and R? is an R1 group, R1 particularly being H or (C1-C6)alkyl group; A1 being an —NH— radical or —NH—CH2— radical; Cy1 particularly being a phenyl group, A is a fused (hetero)aromatic ring having 5 to 7 atoms, for use for treating cancer.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: March 19, 2024
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFQUE, UNIVERSITE D'ORLEANS, UNIVERSITE DE TOURS, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE SCIENTIFIQUE (INSERM), CHU NANTES
    Inventors: Sylvain Routier, Frédéric Buron, Nuno Rodrigues, Gaëlle Fourriere-Grandclaude, Christophe Vandier, Aurélie Chantome, Marie Potier-Cartereau, Maxime Gueguinou, Séverine Marionneau-Lambot
  • RADIOLABELLED COMPOUNDS FOR DIAGNOSING CHOLINERGIC NEURODEGENERATIVE DISEASES
    Publication number: 20240058481
    Abstract: The present invention relates to the radiolabelled compound of enantiomer (R,R) of 5-fluoro-3-4(-phenylpiperidin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol, and to this compound for use thereof in an in vivo diagnosis method, in particular of a cholinergic neurodegenerative disease selected for example from the group formed by Alzheimer's disease, dysmnesia, learning disability, schizophrenia, cognitive dysfunction, hyperactivity disorder, anxiety neurosis, depression, analgesia and Parkinson's disease.
    Type: Application
    Filed: November 23, 2021
    Publication date: February 22, 2024
    Inventors: Sylvain ROUTIER, Frédéric BURON, Franck SUZENET, Nuno RODRIGUES, Sylvie CHALON, Johnny VERCOUILLIE, Denis GUILLOTEAU, Patrick EMOND, Hamid MARZAG
  • Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases
    Patent number: 10906900
    Abstract: The invention relates to compounds of formula (II) for using in imaging and particularly for the diagnosis of neurodegenerative diseases.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: February 2, 2021
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'ORLEANS, UNIVERSITE DE TOURS, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Sylvain Routier, Franck Suzenet, Sylvie Chalon, Frederic Buron, Johnny Vercouillie, Ronald Melki, Liliana Boiaryna, Denis Guilloteau, Laura Pieri
  • ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT
    Publication number: 20210009581
    Abstract: The present invention concerns a compound of following general formula (I): where: either R is an R1 group and R? is an -A1-Cy1 group, or R is an -A1-Cy1 group and R? is an R1 group, R1 particularly being H or (C1-C6)alkyl group; A1 being an —NH— radical or —NH—CH2— radical; Cy1 particularly being a phenyl group, A is a fused (hetero)aromatic ring having 5 to 7 atoms, for use for treating cancer.
    Type: Application
    Filed: May 23, 2018
    Publication date: January 14, 2021
    Inventors: Sylvain ROUTIER, Frédéric BURON, Nuno RODRIGUES, Gaëlle FOURRIERE-GRANDCLAUDE, Christophe VANDIER, Aurélie CHANTOME, Marie POTIER-CARTEREAU, Maxime GUEGUINOU, Séverine MARIONNEAU-LAMBOT
  • COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES
    Publication number: 20190211011
    Abstract: The invention relates to compounds of formula (II) for using in imaging and particularly for the diagnosis of neurodegenerative diseases
    Type: Application
    Filed: September 26, 2017
    Publication date: July 11, 2019
    Inventors: Sylvain ROUTIER, Franck SUZENET, Sylvie CHALON, Frederic BURON, Johnny VERCOUILLIE, Ronald MELKI, Liliana BOIARYNA, Denis GUILLOTEAU, Laura Ronald PIERI
  • Trisubstituted pyrido[2,3-D]pyrimidines, methods for preparing same and therapeutic uses thereof
    Patent number: 10202372
    Abstract: The present invention relates to compounds of the following general formula (I): wherein: R1 is notably a group —NRaRb, Ra and Rb forming together with the nitrogen atom onto which they are bound, a heterocycle comprising from 5 to 30 atoms, R2 is notably an aryl comprising from 5 to 30 atoms, and R3 is notably an alkenyl comprising from 1 to 20 carbon atoms.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: February 12, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), UNIVERSITE D'ORLEANS
    Inventors: Sylvain Routier, Hélène Benedetti, Frédéric Buron, Marie-Aude Hiebel, Thibault Saurat, Gérald Guillaumet
  • TRISUBSTITUTED PYRIDO[2,3-D]PYRIMIDINES, METHODS FOR PREPARING SAME AND THERAPEUTIC USES THEREOF
    Publication number: 20150203489
    Abstract: The present invention relates to compounds of the following general formula (I): wherein: R1 is notably a group —NRaRb, Ra and Rb forming together with the nitrogen atom onto which they are bound, a heterocycle comprising from 5 to 30 atoms, R2 is notably an aryl comprising from 5 to 30 atoms, and R3 is notably an alkenyl comprising from 1 to 20 carbon atoms.
    Type: Application
    Filed: August 16, 2013
    Publication date: July 23, 2015
    Inventors: Sylvain Routier, Hélène Benedetti, Frédéric Buron, Marie-Aude Hiebel, Thibault Saurat, Gérald Guillaumet