Patents by Inventor Frédéric Marion
Frédéric Marion has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11970055Abstract: A blocking device for a front end air inlet of a motor vehicle, comprising at least one stop, a support frame, at least one flap arranged inside the support frame. The at least one flap comprises a first end and a second end. The second end of the at least one flap comprises a release device. The release device comprises a first part and a second part which are connected by a male/female device. The first part of the release device is configured to come into contact with said at least one stop such that the first part and the second part move apart from one another by the rotation of the second part.Type: GrantFiled: January 30, 2020Date of Patent: April 30, 2024Assignee: Valeo Systemes ThermiquesInventors: Frédéric Vacca, Karim Arab, Laura Marion
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Publication number: 20240131920Abstract: The invention relates to a shutter device (1) for a front-end air intake of a motor vehicle, comprising:—a support frame (3),—at least two shutters (5) comprising a shutter body (Sa) and a first end (Sb) connected to the support frame (3). According to the invention, the first end (Sb) of a first shutter (5) comprises a device for disconnecting (60) the first shutter (5), and the first end (Sb) of a second shutter comprises a device for disconnecting (60) the second shutter (5), each disconnection device (60) comprising:—a first portion (61) connected to the shutter body (Sa), and—a second portion (62) arranged opposite the first portion (61), each shutter device (1) comprising at least one stop (9), the first portion (61) and/or the shutter body (Sa) being configured to core into contact with the stop (9).Type: ApplicationFiled: October 7, 2020Publication date: April 25, 2024Applicant: Valeo Systemes ThermiquesInventors: Frédéric Vacca, Laura Marion, Karim Arab
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Publication number: 20230415231Abstract: There are provided reactive metal powder in-flight heat treatment processes. For example, such processes comprise providing a reactive metal powder; and contacting the reactive metal powder with at least one additive gas while carrying out said in-flight heat treatment process, thereby obtaining a raw reactive metal powder.Type: ApplicationFiled: September 7, 2023Publication date: December 28, 2023Inventors: Frédéric Larouche, Frédéric Marion, Matthieu Balmayer
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Patent number: 11794247Abstract: There are provided reactive metal powder in-flight heat treatment processes. For example, such processes comprise providing a reactive metal powder; and contacting the reactive metal powder with at least one additive gas while carrying out said in-flight heat treatment process, thereby obtaining a raw reactive metal powder.Type: GrantFiled: January 28, 2022Date of Patent: October 24, 2023Assignee: AP&C Advanced Powders & Coatings, Inc.Inventors: Frédéric Larouche, Frédéric Marion, Matthieu Balmayer
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Publication number: 20220143693Abstract: There are provided reactive metal powder in-flight heat treatment processes. For example, such processes comprise providing a reactive metal powder; and contacting the reactive metal powder with at least one additive gas while carrying out said in-flight heat treatment process, thereby obtaining a raw reactive metal powder.Type: ApplicationFiled: January 28, 2022Publication date: May 12, 2022Inventors: Frédéric Larouche, Frédéric Marion, Matthieu Balmayer
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Patent number: 11235385Abstract: There are provided reactive metal powder in-flight heat treatment processes. For example, such processes comprise providing a reactive metal powder; and contacting the reactive metal powder with at least one additive gas while carrying out said in-flight heat treatment process, thereby obtaining a raw reactive metal powder.Type: GrantFiled: April 10, 2017Date of Patent: February 1, 2022Assignee: AP&C ADVANCED POWDERS & COATING INC.Inventors: Frédéric Larouche, Frédéric Marion, Matthieu Balmayer
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Publication number: 20220023438Abstract: The present invention relates to a linker of the following formula (I) or a salt thereof: (I). The present invention relates to a linker-drug conjugate of the following formula (II) or a salt thereof: (II). The present invention relates also to a binding unit-drug corrugate, such as an antibody-drug conjugate, of the following formula (III) or (IV) or a salt thereof: (III), (IV), as well as a pharmaceutical composition comprising such a binding unit-drug corrugate and its use in the treatment of cancer.Type: ApplicationFiled: September 27, 2019Publication date: January 27, 2022Applicant: PIERRE FABRE MEDICAMENTInventors: Michel PEREZ, Frédéric MARION, Jean-François HAEUW, Cyrille DREYFUS
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Publication number: 20210178468Abstract: Aluminum-based metallic powders, along with their methods of production and formation, are provided. The Al-based metallic powders are formed with an increased amount of oxygen within at least a portion of the particles of the powder. The Al-based metallic powders show improved flowability.Type: ApplicationFiled: September 25, 2020Publication date: June 17, 2021Inventors: Frederic Larouche, Matthieu Balmayer, Frederic Marion
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Patent number: 10519125Abstract: The invention relates to compounds of the following general formula (I) in the form of one of the enantiomers thereof or a mixture of the enantiomers thereof, and the pharmaceutically acceptable salts and/or solvates thereof, especially for the use thereof as a medicament, more specifically in cancer treatment. The invention also relates to pharmaceutical compositions containing same and to the methods for the production thereof.Type: GrantFiled: December 1, 2017Date of Patent: December 31, 2019Assignee: PIERRE FABRE MEDICAMENTInventors: Frédéric Marion, El Bachir Kaloun, Frédéric Lieby-Muller, Michel Perez, Jean-Philippe Annereau, Laurent Creancier
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Publication number: 20190232365Abstract: There are provided reactive metal powder in-flight heat treatment processes. For example, such processes comprise providing a reactive metal powder; and contacting the reactive metal powder with at least one additive gas while carrying out said in-flight heat treatment process, thereby obtaining a raw reactive metal powder.Type: ApplicationFiled: April 10, 2017Publication date: August 1, 2019Inventors: Frédéric LAROUCHE, Frédéric MARION, Matthieu BALMAYER
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Publication number: 20190001416Abstract: There are provided reactive metal powder atomization manufacturing processes. For example, such processes include providing a heated metal source and contact the heated metal source with at least one additive gas while carrying out the atomization process. Such processes provide raw reactive metal powder having improved flowability. The at least one additive gas can be mixed together with an atomization gas to obtain an atomization mixture, and the heated metal source can be contacted with the atomization mixture while carrying out the atomization process. Reactive metal powder spheroidization manufacturing processes are also provided.Type: ApplicationFiled: October 27, 2016Publication date: January 3, 2019Inventors: Frédéric LAROUCHE, Frédéric MARION, Matthieu BALMAYER
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Patent number: 10047064Abstract: The invention relates to compounds of the following general formula (I) in the form of one of the enantiomers thereof or a mixture of the enantiomers thereof, and the pharmaceutically acceptable salts and/or solvates thereof, especially for the use thereof as a medicament, more specifically in cancer treatment. The invention also relates to pharmaceutical compositions containing same and to the methods for the production thereof.Type: GrantFiled: July 6, 2015Date of Patent: August 14, 2018Assignee: PIERRE FABRE MEDICAMENTInventors: Frédéric Marion, El Bachir Kaloun, Frédéric Lieby-Muller, Michel Perez, Jean-Philippe Annereau, Laurent Creancier
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Publication number: 20180086729Abstract: The invention relates to compounds of the following general formula (I) in the form of one of the enantiomers thereof or a mixture of the enantiomers thereof, and the pharmaceutically acceptable salts and/or solvates thereof, especially for the use thereof as a medicament, more specifically in cancer treatment. The invention also relates to pharmaceutical compositions containing same and to the methods for the production thereof.Type: ApplicationFiled: December 1, 2017Publication date: March 29, 2018Applicant: PIERRE FABRE MEDICAMENTInventors: Frédéric MARION, El Bachir KALOUN, Frédéric LIEBY-MULLER, Michel PEREZ, Jean-Philippe ANNEREAU, Laurent CREANCIER
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Publication number: 20170137400Abstract: The invention relates to compounds of the following general formula (I) in the form of one of the enantiomers thereof or a mixture of the enantiomers thereof, and the pharmaceutically acceptable salts and/or solvates thereof, especially for the use thereof as a medicament, more specifically in cancer treatment. The invention also relates to pharmaceutical compositions containing same and to the methods for the production thereof.Type: ApplicationFiled: July 6, 2015Publication date: May 18, 2017Applicant: PIERRE FABRE MEDICAMENTInventors: Frédéric MARION, El Bachir KALOUN, Frédéric LIEBY-MULLER, Michel PEREZ, Jean-Philippe ANNEREAU, Laurent CREANCIER
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Publication number: 20160289204Abstract: The present invention relates to compounds of the following general formula (I), or to a pharmaceutically acceptable salt thereof, as well as to the uses thereof as a drug, in particular for treating cancerous or precancerous hyperproliferative conditions, and to the pharmaceutical compositions containing same.Type: ApplicationFiled: June 15, 2016Publication date: October 6, 2016Applicant: PIERRE FABRE MEDICAMENTInventors: Frédéric MARION, Frédéric LIEBY-MULLER, Serge GRISONI, Emmannuel FOURNIER
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Patent number: 9416142Abstract: The present invention relates to compounds of the following general formula (I), or to a pharmaceutically acceptable salt thereof, as well as to the uses thereof as a drug, in particular for treating cancerous or precancerous hyperproliferative conditions, and to the pharmaceutical compositions containing same.Type: GrantFiled: August 1, 2013Date of Patent: August 16, 2016Assignee: PIERRE FABRE MEDICAMENTInventors: Frédéric Marion, Frédéric Lieby-Muller, Serge Grisoni, Emmannuel Fournier
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Patent number: 9416143Abstract: The present invention relates to compounds of the following general formula (I), or to a pharmaceutically acceptable salt thereof, as well as to the uses thereof as a drug, in particular in the treatment of cancerous or precancerous hyperproliferative conditions, and to the pharmaceutical compositions containing same.Type: GrantFiled: August 1, 2013Date of Patent: August 16, 2016Assignee: PIERRE FABRE MEDICAMENTInventors: Frédéric Marion, Frédéric Lieby-Muller, Serge Grisoni, Nicolas Rahier, Michel Perez, Isabelle Sartori
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Publication number: 20150210713Abstract: The present invention relates to compounds of the following general formula (I), or to a pharmaceutically acceptable salt thereof, as well as to the uses thereof as a drug, in particular in the treatment of cancerous or precancerous hyperproliferative conditions, and to the pharmaceutical compositions containing same.Type: ApplicationFiled: August 1, 2013Publication date: July 30, 2015Applicant: PIERRE FABRE MEDICAMENTInventors: Frédéric Marion, Frédéric Lieby-Muller, Serge Grisoni, Nicolas Rahier, Michel Perez, Isabelle Sartori
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Publication number: 20150191443Abstract: The present invention relates to compounds of the following general formula (I), or to a pharmaceutically acceptable salt thereof, as well as to the uses thereof as a drug, in particular for treating cancerous or precancerous hyperproliferative conditions, and to the pharmaceutical compositions containing same.Type: ApplicationFiled: August 1, 2013Publication date: July 9, 2015Applicant: PIERRE FABRE MEDICAMENTInventors: Frédéric Marion, Frédéric Lieby-Muller, Serge Grisoni, Emmannuel Fournier
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Patent number: 8697064Abstract: The present invention concerns nitrogenated derivatives of narciclasine and pancratistatin of the following general formula (I) as well as their pharmaceutically acceptable salts. The present invention also concerns the use of these compounds in cancer therapy as well as a method for their preparation.Type: GrantFiled: December 26, 2012Date of Patent: April 15, 2014Assignee: Pierre Fabre MedicamentInventors: Frédéric Marion, Jean-Philippe Annereau, Jacques Fahy