Patents by Inventor Frédéric Revah

Frédéric Revah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of jasmonate ester derivatives for treating benign hyperproliferative skin disorders
    Patent number: 9284252
    Abstract: The present invention relates to methods of treating benign hyperproliferative diseases of the epidermis by administering a composition comprising at least one jasmonate ester derivative. In particular, the present invention provides jasmonate ester derivatives as potent compounds useful for the treatment of disorders such as actinic keratoses with reduced side effects.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: March 15, 2016
    Assignee: SEPAL PHARMA LTD.
    Inventors: Max Herzberg, Frederic Revah
  • USE OF JASMONATE ESTER DERIVATIVES FOR TREATING BENIGN HYPERPROLIFERATIVE SKIN DISORDERS
    Publication number: 20150080430
    Abstract: The present invention relates to methods of treating benign hyperproliferative diseases of the epidermis by administering a composition comprising at least one jasmonate ester derivative. In particular, the present invention provides jasmonate ester derivatives as potent compounds useful for the treatment of disorders such as actinic keratoses with reduced side effects.
    Type: Application
    Filed: September 25, 2014
    Publication date: March 19, 2015
    Applicant: SEPAL PHARMA LTD.
    Inventors: Max HERZBERG, Frederic REVAH
  • Pharmaceutical compositions and utilization thereof particularly for the treatment of neurodegenerative diseases
    Patent number: 8431119
    Abstract: The present invention relates to pharmaceutical compositions that act on the p53 protein or its gene and methods of use for the treatment of neurodegenerative diseases.
    Type: Grant
    Filed: August 22, 2007
    Date of Patent: April 30, 2013
    Assignee: Aventis Pharma S.A.
    Inventors: Jacques Mallet, Frederic Revah, Jean-Marie Stutzmann
  • USE OF JASMONATE ESTER DERIVATIVES FOR TREATING BENIGN HYPERPROLIFERATIVE SKIN DISORDERS
    Publication number: 20120083529
    Abstract: The present invention relates to methods of treating benign hyperproliferative diseases of the epidermis by administering a composition comprising at least one jasmonate ester derivative, preferably methyl jasmonate. In particular, the present invention provides jasmonate ester derivatives as potent compounds useful for the treatment of disorders such as actinic keratoses with reduced side effects.
    Type: Application
    Filed: June 3, 2010
    Publication date: April 5, 2012
    Applicant: SEPAL PHARMA LTD
    Inventors: Max Herzberg, Frederic Revah
  • SEPARATION METHOD OF BIOLOGICAL OBJECTS RELATIVE TO THEIR VISCOELASTIC PROPERTIES
    Publication number: 20100248207
    Abstract: The present invention relates to a method for the separation of biological objects in a solution which have different viscoelastic properties, wherein said method comprises a filtration step allowing the higher viscoelastic biological objects to pass through the membrane while retaining the lower viscoelastic biological objects above the membrane, and a recovery step wherein the separated lower viscoelastic biological objects are recovered above or onto the membrane and/or the separated higher viscoelastic biological objects are recovered in the filtrate. Advantageously, the biological objects are cells. More advantageously, the recovered cells are viable cells. In one preferred embodiment, the cells are tumor cells. In another preferred embodiment, the cells are fetal cells and the method finds an application in prenatal diagnosis.
    Type: Application
    Filed: June 19, 2009
    Publication date: September 30, 2010
    Applicants: HERA DIAGNOSTICS, CANOPUS BIOSCIENCE LTD.
    Inventors: Ryan Raz, Anthony Presta, Laurent Safar, Frédéric Revah
  • SEPARATION AND SORTING OF DIFFERENT BIOLOGICAL OBJECTS
    Publication number: 20090170199
    Abstract: The present invention relates to a method for the separation of biological objects in a solution which have different viscoelastic properties, wherein said method comprises a filtration step allowing the higher viscoelastic biological objects to pass through the membrane while retaining the lower viscoelastic biological objects above the membrane, and a recovery step wherein the separated lower viscoelastic biological objects are recovered above or onto the membrane and/or the separated higher viscoelastic biological objects are recovered in the filtrate. Advantageously, the biological objects are cells. More advantageously, the recovered cells are viable cells. In one preferred embodiment, the cells are tumor cells. In another preferred embodiment, the cells are fetal cells and the method finds an application in prenatal diagnosis.
    Type: Application
    Filed: June 19, 2008
    Publication date: July 2, 2009
    Inventors: Ryan Stephen RAZ, Anthony PRESTA, Laurent SAFAR, Frederic REVAH
  • PHARMACEUTICAL COMPOSITIONS AND UTILIZATION THEREOF PARTICULARLY FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
    Publication number: 20080032284
    Abstract: The present invention relates to pharmaceutical compositions that act on the p53 protein or its gene and methods of use for the treatment of neurodegenerative diseases.
    Type: Application
    Filed: August 22, 2007
    Publication date: February 7, 2008
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Jacques MALLET, Frederic REVAH, Jean-Marie STUTZMANN
  • Pharmaceutical compositions and utilization thereof particularly for the treatment of neurodegenerative disorders
    Patent number: 7273854
    Abstract: The present invention relates to pharmaceutical compositions that act on the p53 protein or its gene and methods of use for the treatment of neurodegenerative diseases.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: September 25, 2007
    Assignee: sanofi-aventis
    Inventors: Jacques Mallet, Frédéric Revah, Jean-Marie Stutzmann
  • Adenovirus comprising a gene coding for glutathione peroxidase
    Patent number: 7241591
    Abstract: The present invention relates to a defective adenovirus comprising at least a DNA sequence coding for all or an active part of glutathione peroxidase or a derivative thereof. It also relates to their utilization in therapy and to the corresponding pharmaceutical compositions.
    Type: Grant
    Filed: February 2, 2004
    Date of Patent: July 10, 2007
    Assignee: Aventis Pharma S.A.
    Inventors: Martine Barkats, Jacques Mallet, Frédéric Revah
  • Use of alverine, alone or in combination with a tricyclic antidepressant or an antidepressant which is a specific inhibitor of serotonin reuptake for treatment of depression
    Publication number: 20060223891
    Abstract: The present invention relates to the utilisation of Alverine or its metabolites, alone or in combination with a tricyclic antidepressant or a specific inhibitor antidepressant of serotonin recapture, for the preparation of pharmaceutical compositions for the treatment of depression.
    Type: Application
    Filed: June 11, 2004
    Publication date: October 5, 2006
    Inventors: Jacques Migeon, Frédéric Revah
  • Adenovirus including a gene coding for a superoxide dismutase
    Publication number: 20050244381
    Abstract: A defective recombinant adenovirus including at least one DNA sequence coding for all or an active part of a superoxide dismutase or a derivative thereof. The therapeutical use thereof and corresponding pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: June 16, 2005
    Publication date: November 3, 2005
    Inventors: Jacques Mallet, Frederic Revah, Michel Perricaudet, Martine Barkats
  • Recombinant adenoviruses encoding glial cell neurotrophic factor (GDNF)
    Publication number: 20050069523
    Abstract: Recombinant adenoviruses comprising a heterologous DNA sequence coding for glial-derived neurotrophic factor (GDNF), preparation thereof, and use thereof for treating and/or preventing degenerative neurological diseases.
    Type: Application
    Filed: July 9, 2003
    Publication date: March 31, 2005
    Inventors: Philippe Horellou, Jacques Mallet, Michel Perricaudet, Frederic Revah, Emmanuelle Vigne
  • Utilization of alverine, alone or in combination with tricyclic antidepressant or a specific serotonin reuptake inhibitor for the treatment of depression
    Publication number: 20050065218
    Abstract: The present invention relates to the utilization of Alverine or its metabolites, alone or in combination with a tricyclic antidepressant or a specific serotonin reuptake inhibitor, for the preparation of pharmaceutical compositions for the treatment of depression.
    Type: Application
    Filed: June 14, 2004
    Publication date: March 24, 2005
    Inventors: Jacques Migeon, Frederic Revah
  • Adenovirus comprising a gene coding for glutathione peroxidase
    Publication number: 20040175363
    Abstract: The present invention relates to a defective adenovirus comprising at least a DNA sequence coding for all or an active part of glutathione peroxidase or a derivative thereof. It also relates to their utilisation in therapy and to the corresponding pharmaceutical compositions.
    Type: Application
    Filed: February 2, 2004
    Publication date: September 9, 2004
    Applicant: Aventis Pharma S.A.
    Inventors: Martine Barkats, Jacques Mallet, Frederic Revah
  • Method for treating amyotrophic lateral sclerosis
    Patent number: 6723315
    Abstract: The invention concerns a novel method for treating motor neuron diseases and particularly amyotrophic lateral sclerosis. It consists more particularly in the systemic administration of expression systems of neurotrophic factors.
    Type: Grant
    Filed: March 22, 1999
    Date of Patent: April 20, 2004
    Assignee: Aventis Pharma S.A.
    Inventors: Jacques Mallet, Philippe Kennel, Frédéric Revah, Axel Kahn, Georg Haase
  • Recombinant adenoviruses coding for basic fibroblast growth factors (BFGF)
    Patent number: 6685934
    Abstract: Recombinant adenoviruses comprising a heterologous DNA sequence coding for basic blast growth factors (bFGF), preparation and uses thereof for the treatment and/or prevention of neurodegenerative diseases.
    Type: Grant
    Filed: October 9, 1996
    Date of Patent: February 3, 2004
    Assignee: Aventis Pharma S.A.
    Inventors: Jacques Mallet, Michel Perricaudet, Emmanuelle Vigne, Frédéric Revah, Marc Abitbol, Paul Roustan
  • Adenoviral-vector-mediated gene transfer into medullary motor neurons
    Patent number: 6632427
    Abstract: The present invention relates to methods and compositions for delivering a nucleic acid to motor neurons administering the nucleic acid to muscle tissue. The invention relates to methods for treating pathologies of the nervous system, such as trauma and neurodegenerative diseases.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: October 14, 2003
    Assignees: Aventis Pharma S.A., Institut National de la Sante et de la Recherche Medicale
    Inventors: Françoise Finiels, Minerva Gimenez-Ribotta, Jacques Mallet, Alain Privat, Frédéric Revah
  • Muscle reinnervation and motor axon sprouting by administering DNA sequences encoding NT-3 and CNTF
    Patent number: 6552003
    Abstract: The present invention relates to methods and compositions for delivering nucleic acids to motor neurons by administering the nucleic acids to muscle tissue. The invention relates to methods for treating pathologies of the nervous system, such as trauma and neurodegenerative diseases.
    Type: Grant
    Filed: July 16, 1999
    Date of Patent: April 22, 2003
    Assignees: Aventis Pharma S.A., Institut National de la Sante et de la Recherche Medicale ( INSERM)
    Inventors: Françoise Finiels, Minerva Gimenez-Ribotta, Jacques Mallet, Alain Privat, Frédéric Revah
  • ADENOVIRUS INCLUDING A GENE CODING FOR A SUPEROXIDE DISMUTASE
    Publication number: 20030059455
    Abstract: A defective recombinant adenovirus including at least one DNA sequence coding for all or an active part of a superoxide dismutase or a derivative thereof. The therapeutical use thereof and corresponding pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: January 13, 1997
    Publication date: March 27, 2003
    Applicant: RHONE-POULENC RORER S.A.
    Inventors: MARTINE BARKATS, JACQUES MALLET, MICHEL PERRICAUDET, FREDERIC REVAH
  • ADENOVIRAL-VECTOR-MEDIATED GENE TRANSFER INTO MEDULLARY MOTOR NEURONS
    Publication number: 20020164303
    Abstract: The present invention relates to methods and compositions for delivering nucleic acids to motor neurons by administering the nucleic acids to muscle tissue. The invention relates to methods for treating pathologies of the nervous system, such as trauma and neurodegenerative diseases.
    Type: Application
    Filed: July 16, 1999
    Publication date: November 7, 2002
    Inventors: FRANCOISE FINIELS, MINERVA GIMENEZ-RIBOTTA, JACQUES MALLET, ALAIN PRIVAT, FREDERIC REVAH