Patents by Inventor Frédéric Sauveur

Frédéric Sauveur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5705525
    Abstract: The invention relates to thiophene compounds of formula: ##STR1## wherein: X.sub.1, X.sub.2, Y.sub.1 and Y.sub.2, which are identical or different, each represents hydrogen or halogen, (C.sub.1 -C.sub.5)-alkyl oralkoxy, or trifluoromethyl,R.sub.1 represents hydrogen or (C.sub.1 -C.sub.5)-alkyl,A represents a straight (C.sub.1 -C.sub.5)-hydrocarbon chain of which each carbon atom is optionally mono- or di-substituted by a (C.sub.1 -C.sub.5)-alkyl, andR.sub.2 represents hydrogen, (C.sub.1 -C.sub.6)-alkyl, cyclohexyl or benzyl;and their physiologically tolerable salts.The products of the invention may be used as anti-inflammatory agents.
    Type: Grant
    Filed: February 22, 1996
    Date of Patent: January 6, 1998
    Assignee: Adir et Compagnie
    Inventors: Michel Wierzbicki, Frederic Sauveur, Jacqueline Bonnet, Charles Tordjman
  • Patent number: 5703074
    Abstract: Thiophene compounds of formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are as defined in the description, and salts thereof with appropriate acids.Those compounds and their physiologically tolerable salts can be used as medicaments in the treatment of pathologies characterized by a loss of bone tissue.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: December 30, 1997
    Assignee: Adir Et Compagnie
    Inventors: Michel Wierzbicki, Frederic Sauveur, Marie-Francoise Boussard, Jacqueline Bonnet, Massimo Sabatini
  • Patent number: 5175294
    Abstract: New thiophene compounds of the formula: ##STR1## in which: X represents hydrogen, halogen, C.sub.1 -C.sub.5 alkyl or alkoxy or dialkylamino;n represents 1 or 2;a represents an integer of from 2 to 6;b represents 2 or 3;c represents 1 or 2, and is such that b+c=4;R.sub.1 and R.sub.2 represent hydrogen or (C.sub.1 -C.sub.5)alkyl, or together with the carbon atom to which they are bonded form a hydrocarbon ring containing from 3 to 6 carbon atoms; andR and R' represent hydrogen or (C.sub.1 -C.sub.5)alkyl, or together with the nitrogen atom to which they are bonded form a pentagonal or hexagonal heterocycle optionally containing an oxygen atom or a second nitrogen atom which may itself be substituted; and their physiologically tolerable salts.The products of the invention can be used therapeutically especially in the treatment of pathologies that are characterized by a loss of bone tissue.
    Type: Grant
    Filed: August 5, 1991
    Date of Patent: December 29, 1992
    Assignee: Adir et Compagnie
    Inventors: Michel Wierzbicki, Frederic Sauveur, Jacqueline Bonnet, Martine Brisset, Charles Tordjman
  • Patent number: 5061704
    Abstract: 1. New thiophene compounds of the formula: ##STR1## in which: X represents hydrogen, halogen, C.sub.1 -C.sub.5 alkyl or alkoxy or dialkylamino;n represents 1 or 2;a represents an integer of from 2 to 6;b represents 2 or 3;c represents 1 or 2, and is such that b+c=4;R.sub.1 and R.sub.2 represent hydrogen or (C.sub.1 -C.sub.5)alkyl, or together with the carbon atom to which they are bonded form a hydrocarbon ring containing from 3 to 6 carbon atoms; andR and R' represent hydrogen or (C.sub.1 -C.sub.5)alkyl, or together with the nitrogen atom to which they are bonded form a pentagonal or hexagonal heterocycle optionally containing an oxygen atom or a second nitrogen atom which may itself be substituted; and their physiologically tolerable salts.The products of the invention can be used therapeutically especially in the treatment of pathologies that are characterized by a loss of bone tissue.2.
    Type: Grant
    Filed: November 23, 1990
    Date of Patent: October 29, 1991
    Assignee: Adir et Compagnie
    Inventors: Michel Wierzbicki, Frederic Sauveur, Jacqueline Bonnet, Martine Brisset, Charles Tordjman
  • Patent number: RE37078
    Abstract: The invention relates to thiophene compounds of formula: wherein: X1, X2, Y1 and Y2, which are identical or different, each represents hydrogen or halogen, (C1-C5)-alkyl or alkoxy, or trifluoromethyl, X1 and Y1, which are identical or different, each represents C1-C5 alkoxy, X2 and Y2 each represents hydrogen, R1 represents hydrogen or (C1-C5)-alkyl, A represents a straight (C1-C5)-hydrocarbon chain of which each carbon atom is optionally mono- or di-substituted by a (C1-C5)-alkyl, and R2 represents hydrogen, (C1-C6)-alkyl, cyclohexyl or benzyl; and their physiologically tolerable salts. The products of the invention may be used as anti-inflammatory agents.
    Type: Grant
    Filed: August 3, 1999
    Date of Patent: February 27, 2001
    Assignee: Adir et Compagnie
    Inventors: Michel Wierzbicki, Frédéric Sauveur, Jacqueline Bonnet, Charles Tordjman